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A non-orthogonal Gaussian function expansion of vertical reflectivity profiles is proposed. In conjunction with a generalization of a previously published formula this allows bistatic radar cross-sections to be calculated rapidly for hydrometeor scatter problems involving arbitrary reflectivity profiles. In particular, it allows scattering from melting band and ice regions to be included in the cross-section calculation. Copyright © 2000 John Wiley & Sons, Ltd. [ABSTRACT FROM AUTHOR]

A formula is derived for the effective bistatic radar cross-section of a rain cell with Gaussian reflectivity profile assuming antennas with Gaussian radiation patterns. The size and location of the rain cell are arbitrary, as is the bistatic scattering geometry. The expression is analytical, avoiding the need for numerical integration, and general, allowing treatment of cases with only partial beam intersection. Using a recently proposed model, sidelobe contributions and multiple cells embedded within widespread rain debris can be incorporated. [ABSTRACT FROM AUTHOR]

The sequences of urokinase (UK) and tissue-type plasminogen activator (TPA) were aligned with those of chymotrypsin, trypsin, and elastase according to their 'structurally conserved regions'. In spite of its trypsin-like specificity UK was model-built on the basis of the chymotrypsin structure because of a corresponding disulfide pattern. The extra disulfide bond falls to cysteines 50 and 111d. Insertions can easily be accommodated at the surface. As they occur similarly in both, UK and TPA, a role in plasminogen recognition may be possible. Of the functional positions known to be involved in substrate or inhibitor binding, Asp 97, Lys 143 and Arg 217 (Leu in TPA) may contribute to plasminogen activating specificity. PTI binding may in part be impaired by structural differences at the edge of the binding pocket.