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PURPOSE: To analyze a single institution's experience of solitary venous malformation (VM) in the accessory parotid region. METHODS: From 2002 to 2009, a total of 10 consecutive patients with solitary venous malformation (VM) in the accessory parotid region were retrospectively analyzed. Clinical records were reviewed for patient demographic data, presenting symptoms and signs, imaging modalities used, histological and immunohistochemical results, surgical data, and clinical outcomes. RESULTS: The sample consisted of 5 males and 5 females with a mean age of 42.8 years. The course of disease ranged from 0.5 to 168.0 months with a mean time of 64.9 months. The mean size of the masses was 1.7 cmx1.5 cm (1.0 cmx0.8 cm to 2.5 cmx2.5 cm). Investigations included Doppler ultrasonography (US) and computed tomography (CT) scanning. Surgical excision using various surgical approaches was performed in all patients. Postoperative pathologic examination confirmed the diagnosis of VM. The mean follow-up period was 41.2 months (range 2 months to 94 months) with no recurrence reported. CONCLUSIONS: For solitary VM in the accessory parotid region, investigations, such as Doppler US or CT scanning or the use of fine needle aspiration cytology, may aid in clinical diagnosis. The primary treatment of these lesions is surgical excision, and the prognosis is good with fewer recurrence. [ABSTRACT FROM AUTHOR]

PURPOSE: To evaluate the effect of decompression for large mandibular odontogenic keratocystic tumours in adolescents. METHODS: Fifteen cases of large odontogenic keratocystic tumours in mandible underwent decompression from Feb.2005 to Feb. 2011, the average age of the patients was 19.3 years. Patients were follow-up by X-ray every 2-3 months, and every 6-12 months by CT. Subsequent curettage was given when the remaining tumours were less than 2cm in diameter. RESULTS: The decompression period lasted from 12 to 18 months, with an average time of 13.6 months. After decompression, bone regeneration was noticed on radiographs, the average decrement percentage of the tumour size was 41.5% at 6-month, 61.5% at 12-month and 81.8% at 18-month after operation. All patients were followed up for 1-5 years after secondary surgical curettage, no recurrence was observed. CONCLUSION: Decompression is a preferred treatment for large mandibular odontogenic keratocystic tumours in adolescents. [ABSTRACT FROM AUTHOR]

PURPOSE: To investigate the proportion of salivary gland tumors in the elder patients in the past ten years, in order to provide reference for clinical diagnosis and treatment. METHODS: The medical data of salivary gland tumors treated in our department from January 2000 to December 2009 were reviewed and analyzed. The changes of three periods between 21cl0s, 20c90s and 20c80s were compared. RESULTS: The number of salivary gland tumors in elder patients increased rapidly in recent years, especially that of benign tumors. Warthin's tumor was the most common benign tumors, and adenoid cystic carcinoma was most often found in malignant tumors. Carcinoma ex pleomorphic adenoma rose to the third among malignant tumors of salivary gland and first among parotid gland malignancies. The proportion of benign tumor was almost equal to malignant tumor in minor salivary gland. The benign-malignant ratio of palatal salivary gland was 1.34:1, which was opposite to the previous figure. The parotid gland was the most common site, followed by palatal and submandibular gland. CONCLUSIONS: The proportion of salivary gland tumors in elder patients in 2000s was different from that in 1980s and 1990s. The changes should be taken into attention in daily clinical works. [ABSTRACT FROM AUTHOR]

PURPOSE: To analyze a single institution's experience in the clinical management of intraoral lymphoepithelial cyst (LEC) based on clinical examinations differential diagnosis, treatment and prognosis. METHODS: From 1993 to 2010, a total of 120 consecutive patients with intraoral LEC undergoing surgery were retrospectively investigated with regards to gender, age, primary site, symptom, clinical examination, treatment and prognosis. RESULTS: Of the 120 patients, 37 were males and 83 were females, their age ranged from 2 to 75 years with a mean age of 44.1 years. The course of disease ranged from 2 months to 10 years with a mean period of 8.0 months, and 75.8% of the patients had a course of disease shorter than 6 months. The most common location was the tongue (50%) and floor of mouth (38.3%). All patients underwent complete surgical removal of the lesions. During the follow-up period, no lesion recurred. CONCLUSIONS: The clinical characteristics of intraoral LEC are not specific and may be mixed with other intraoral lesions. The first choice of treatment is surgical excision, which results in a good prognosis. Supported by Program for Innovative Research Team of Shanghai Municipal Education Commission and Research Fund of Science and Technology Commission of Shanghai Municipality(1052nm04700, 10140902200). [ABSTRACT FROM AUTHOR]

It's uncommon for lipoma growing beneath the mucusa of the floor of mouth. A case of lipoma in the floor of mouth was reported. The clinical feature and key points of treatment were discussed based on literature review. [ABSTRACT FROM AUTHOR]

PURPOSE: To analyse the clinical features and treatment of ectopic meningioma (EM) in oral and maxillofacial region. METHODS: Twenty-three cases of EM in the oral and maxillofacial region from 1990 to 2008 were reviewed. The clinical features, image findings, surgical treatment and follow-up results were analyzed. RESULTS: The median age of these patients was 37 years old and there was no gender predilection, but there were more female patients in the group of over 40 years old. The primary sites of the tumor were parapharyngeal space (13), infratemporal space/ pterygopalatine space(5), temporal region(3),orbital area (1) and buccal mucosa(l). The CT image of EM in the oral and maxillofacial region was similar to that in the brain. All 23 cases underwent surgical treatment, seventeen cases underwent the tumor totally resected and 6 cases underwent partially resected. Twelve cases were followed up, in which 3 cases recurred and 8 cases had a long-term nerve injury. CONCLUSIONS: EM in the oral and maxillofacial region mainly occurs in adolescent, middle-aged patients and females over 40 years old. The predilection site of the tumor is the deep space of oral and maxillofacial region with adherence to the cervical sheath and lower cranial nerves. Preoperative CT scan is helpful for diagnosis. The main choice of treatment is total resection. The main complication is nerve injury. Supported by Research Fund of Science and Technology Commission of Shanghai Municipality (Grant No. 08DZ2271100). [ABSTRACT FROM AUTHOR]

PURPOSE: To analyze the clinical manifestation, image features, treatment and prognosis of Castleman disease hyaline vascular type in the parotid and neck region. METHODS: From 2004 to 2008, clinical data from ten patients with Castleman disease hyaline vascular type in the parotid and neck region were retrospectively reviewed, including sex, age, primary site, course of disease, symptom, physical examination, image examination, treatment protocol, pathological diagnosis, and follow-up result. RESULTS: Among the ten patients, there were four men and six females, their age ranged from 13 to 54 years with a mean age of 26.6 years. The course of disease ranged from 3 months to 4 years with a mean of 12.5 months. The primary lesions included the parotid region in 3 patients, neck in 5 patients, parotid and neck region in 2 patients. All patients had no obvious complaint and the laboratory examination was within the normal range. Computerized tomography and magnetic resonance imaging /angiography showed some clinical value for differential diagnosis. All patients received surgical operation, during the follow-up period from 6 to 57 months, mean 35.9 months, no recurrence of the lesion occurred. CONCLUSIONS: Castleman disease hyaline vascular type in the parotid and neck region is difficult to be diagnosed clinically, computerized tomography and magnetic resonance/ angiography are somewhat useful for differential diagnosis. Surgical operation is the first-line treatment of choice for this disease with good prognosis. [ABSTRACT FROM AUTHOR]

PURPOSE: This study aims to investigate the correlation between the thickness of the tongue carcinoma and cervical lymph node metastasis obtained with ultrasonography. METHODS: The tumor thickness of 37 primary tongue cancers were measured in the sonogram by the intraoral ultrasonography. The cervical lymph nodes were scanned, and the number, size, internal echo, and blood stream were measured to evaluate the nature. SAS6.1 software package was used for Chi-square test, non-parametric test and Logistic regression. RESULTS: The tumor thickness measured before operation with ultrasonngraphy and after operation from pathological sections was subjected to non-parameter Wilcox rank-sum test. P=0.2013, indicating that there was no significant difference between the mean thickness obtained from the two modalities. The tumor thickness and cervical lymph node metastasis were subjected to non-parameter rank correlation test, the Spearman r=0.6824,P<0.01, indicating that there were a positive correlation between the tumor thickness measured by ultrasonography scan and cervical lymph node metastasis. Logistic regression analysis also showed that the risk of metastasis of the neck lymph nodes increased with the increased thickness of the tumors. CONCLUSIONS: The accuracy and sensitiveness of ultrasonography in measuring the tumor thickness and detection of cervical lymph metastases make it a promising pre-operative tool in staging the cancer and optimizing the treatment plan for the surgeons. [ABSTRACT FROM AUTHOR]

To investigate the clinical manifestation of branchial cleft cyst (fistula) and provide some clinical experience on its diagnosis and treatment. METHODS: From June 1993 to December 2006, two hundred and eighty-four patients with branchial cleft cyst or fistula underwent surgical treatment were retrospectively reviewed, the preoperative examinations, preoperative diagnosis and postoperative pathological diagnosis were recorded, and the data was analyzed with SAS6.12 software package. RESULTS: Among the 284 patients with branchial cleft cyst of fistula confirmed by postoperative pathological diagnosis, there were 132 patients (46.5%) with first branchial cleft cyst or fistula, one hundred and forty-five patients (51.1%) with second branchial cleft cyst or fistula, and 7 patients (2.4%) with third branchial cleft cyst of fistula. First branchial cleft cyst or fistula often occurred in patients older than 40 years, second and third branchial cleft cyst or fistula often occurred in patients younger than 40 years. The pathological diagnosis confirmed 188 primary lesions, thirty-three recurrent lesions, forty-four lesions with internal fistula, fourteen lesions with secondary infection and external fistula, and three lesions with both internal and external fistulae. One patient was found with tuberculosis simultaneously, two patients with multiple cysts, one patient with venous malformation. Six lesions were found malignant, five from first branchial cleft and one from second brancial cleft. The highest accuracy of preoperative diagnosis was 66.20% using ultrasonography. During the follow-up period, 5.98% of patients had recurrence. CONCLUSIONS: First and second branchial cleft cysts (fistula) are the most common lesions. Preoperative ultrasonography is the first choice for diagnosis of branchial cleft cyst (fistula). Complete resection including the cyst and fistula is the key to successful surgical treatment. [ABSTRACT FROM AUTHOR]

PURPOSE: To investigate the clinical manifestation of branchial cleft cyst (fistula) and provide some clinical experience on its diagnosis and treatment. METHODS: From June 1993 to December 2006, two hundred and eighty-four patients with branchial cleft cyst or fistula underwent surgical treatment were retrospectively reviewed, the preoperative examinations, preoperative diagnosis and postoperative pathological diagnosis were recorded, and the data was analyzed with SAS6.12 software package. RESULTS: Among the 284 patients with branchial cleft cyst or fistula confirmed by postoperative pathological diagnosis, there were 132 patients (46.5%) with first branchial cleft cyst or fistula, one hundred and forty-five patients (51.1%) with second branchial cleft cyst or fistula, and 7 patients (2.4%) with third branchial cleft cyst or fistula. First branchial cleft cyst or fistula often occurred in patients older than 40 years, second and third branchial cleft cyst or fistula often occurred in patients younger than 40 years. The pathological diagnosis confirmed 188 primary lesions, thirty-three recurrent lesions, forty-four lesions with internal fistula, fourteen lesions with secondary infection and external fistula, and three lesions with both internal and external fistulae. One patient was found with tuberculosis simultaneously, two patients with multiple cysts, one patient with venous malformation. Six lesions were found malignant, five from first branchial cleft and one from second branchial cleft. The highest accuracy of preoperative diagnosis was 66.20% using ultrasonography. During the follow-up period, 5.98% of patients had recurrence. CONCLUSIONS: First and second branchial cleft cysts (fistula) are the most common lesions. Preoperative ultrasonography is the first choice for diagnosis of branchial cleft cyst (fistula). Complete resection including the cyst and fistula is the key to successful surgical treatment. [ABSTRACT FROM AUTHOR]

PURPOSE: To evaluate the application of autologous bone fresh-frozen and re-implantation in treatment of cranio-maxillofacial bone tumors. METHODS: Four cases with cranio-maxillofacial bone tumors, including one in the frontal bone and three in the mandible, underwent osteoectomy, autologous diseased bone fresh-frozen by nitrogen, reimplantation of the bone and internal fixation by titanium plate to treat the bone tumor and reconstruct the bone defect. RESULTS: All four cases had one-stage healing 10-14 days after operation. One patient had pathological bone fracture 2 months postoperatively, the other three patients were well-cured without tumor recurrence and gained satisfied cosmetic appearance during 6 months to 3 years of follow-up. The X-ray films showed that the frozen bone was substituted by new bone formation. CONCLUSIONS: Autologous bone fresh-frozen and re-implantation is a feasible method in cranio-maxillofacial bone tumor treatment, especially for young patients. It make possible to do radical surgery and reconstruct the bone defect simultaneously, and is thus worthy of clinical application. [ABSTRACT FROM AUTHOR]