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Objective: The most common cause of acute abdomen requiring surgical intervention globally is acute appendicitis (AA). In this study, we aimed to investigate how AA diagnosis is affected by seasonal changes in Central Anatolia. Materials and Methods: In this study, patients who underwent appendectomy with the diagnosis of (AA) between January 1, 2015 and January 1,2019 were evaluated retrospectively. We divided the patients into three groups based on their histopathological results: Group 1 Acute Appendicitis (AA), Group 2 Appendix vermiformis (AV) and Group 3 Perforated appendicitis (PA). Patients were evaluated concerning age, sex and season of operation. Results: Seven hundred ninety-five patients participated in our study. They were separated into the following groups: Group 1 (n=614), Group 2 (n=125), and Group 3 (n=56). Concerning the sex variable, no statistically significant differences were found between the groups (p=0.061). The mean age of the patients in the perforated appendicitis group was higher when compared to the other groups (p=0.001). When evaluated by season, it was seen that during winter, the patients in Group 1 were significantly higher than the patients in the other groups (p=0.009). In our study, acute appendicitis was most frequently diagnosed during winter (28.7%); appendix vermiformis was most frequently diagnosed during spring (32%) and perforated appendicitis was most frequently diagnosed during summer (41%). Conclusion: Although the diagnosis of acute appendicitis varies seasonally, age and seasonal changes may be effective in the frequency of acute appendicitis. In Central Anatolia, the incidence of acute appendicitis increased during winter, while the rate of perforated appendicitis increased in summer and the rate of negative appendectomy increased in spring.

WOS: 000485683800007 Objective: Formation of gallbladder stone is frequently observed after resection for gastric cancer. Extended lymph dissection is shown to be among risk factors. Materials and Methods: We compared patients with limited lymphatic dissection (D1) and extended lymphatic dissection (D2) in terms of gallstone formation and complications. Results: We observed gallbladder stone formation in 13 (12.8%) patients. Gallbladder stone formation was observed in 11.1% of patients in the D1 group and in 14.3% of patients in the D2 group, but no statistically significant difference was found between lymphatic dissections. Of 13 patients, 5 (38.4%) were symptomatic and 3 (23.1%) developed choledocholithiasis. Five patients who were symptomatic were operated without any problems. The groups did not show a statistically significant difference in terms of cumulative survival times. While patients who underwent D2 dissection had more formed gallbladder stone, there were no significant differences between the groups. Conclusion: The complications related to gallbladder stone developed after gastrectomy can be safely managed.