1. Neutropenia Accompanying Parvovirus B19 Infection after Gynecologic Surgery.
- Author
-
Honda, Ken-ichi, Ishiko, Osamu, Tsujimura, Akemi, Hino, Masayuki, Hirai, Kouzo, Itoh, Fumihiro, Tanaka, Tetsuji, and Ogita, Sachio
- Subjects
- *
PARVOVIRUSES , *PARVOVIRUS diseases , *NEUTROPENIA , *RETICULOCYTES , *FIBRIN tissue adhesive , *BLOOD plasma substitutes , *BLOOD cell count , *GYNECOLOGIC surgery , *GRANULOCYTE-colony stimulating factor , *SERUM , *SURGICAL hemostasis , *NEUTROPHILS - Abstract
The hematologic data and symptoms of 7 patients seropositive for parvovirus B19 IgM antibody after gynecologic surgery were analysed. Parvovirus may have been transmitted by fibrin glue prepared from heat-treated human plasma and used for hemostasis during surgery. The peripheral blood neutrophil count decreased to below 1 × 10[sup 9] /l between postoperative day (POD) 10 and 18, but recovered spontaneously to within the normal range. G-CSF injection was effective in preventing neutropenia or obtaining a prompt recovery. The reticulocyte count fell below 10 × 10[sup 9] /l between POD 13 and 19, and also recovered spontaneously. A slapped-cheek rash was not observed in any of the 7 patients.Copyright © 2000 S. Karger AG, Basel [ABSTRACT FROM AUTHOR]
- Published
- 2000
- Full Text
- View/download PDF