1. Regular silicone and fluorosilicone oil in the prevention of retinal detachment caused by experimental proliferative vitreoretinopathy.
- Author
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Alghadyan A, Peyman GA, Fizer C, Tawakol M, Liu KR, Yue B, and Peace JH
- Subjects
- Animals, Eye Diseases complications, Eye Diseases etiology, Fibroblasts transplantation, Retinal Detachment etiology, Retinal Diseases etiology, Retinal Detachment prevention & control, Retinal Diseases complications, Silicone Oils, Vitreous Body
- Abstract
The effect of both regular silicone and fluorosilicone in preventing retinal detachment caused by experimental proliferative vitreoretinopathy was studied in rabbit eyes which received 250,000 fibroblasts after vitrectomy and lensectomy. In the control group, 14 out of 20 eyes which received fibroblasts had retinal detachments with disorganization of internal structures. In eyes receiving fibroblast and regular silicone, 4 out of 20 eyes had shallow retinal detachment. In the eyes receiving fibroblasts and fluorosilicone, 5 of 28 eyes had shallow retinal detachment. Our findings indicate that both regular silicone and fluorosilicone were effective in preventing retinal detachments caused by experimental proliferative vitreoretinopathy. There was no statistical difference between the two silicone oils.
- Published
- 1988
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