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A comprehensive phytochemical analyses of six different botanicals obtained from Sargassum wightii on GC-MS has revealed the presence of various chemicals. All these identifications were further authenticated by the retention indices and relative retention times. These extracts and fractions contained volatile, non-polar and moderately polar constituents among which 81 were identified. Out of these, 33 were natural constituents while 48 were anthropogenic contaminants. Identified phytochemicals belong to different classes of natural products including 23 fatty acids, 2 fatty aldehydes, 2 fatty alcohols, 2 phytosterols and 4 terpenoids. 15 phytochemicals including 5 fatty acids, methyl iso-pentadecanoate (37), methyl pentadecylate (40), isopropyl myristate (41), methyl elaidate (56) and 9Z,12EOctadecadienoic acid ME (60); 2 fatty aldehydes, nonanal (16) and 2E-decenal (20); 2 fatty alcohols, lignocerol (68) and pentacosyl alcohol (73); 4 isoprenoids, phytane (36), iso-phytol (42), hexahydrofarnesyl acetone (43) and E-phytol (57) and 2 phytosteroids, -Sitosterol (79) and fucosterol (81) were identified for the first time from S. wightii. 48 environmental contaminants included 28 petrochemicals (17 aliphatic, 6 aromatic and 5 oxygenated hydrocarbons), 14 cyclosiloxanes and 6 phthalates. Few of these hydrocarbons are reported from different seaweeds including S. wightii but current study is reporting these as environmental contaminant. Similarly identified hydroperoxides 1-Methyl-pentyl hydroperoxide (9) and 1-ethyl-butyl hydoperoxide (10) could be the oxidative products of 2- hexanone (3) and 3-hexanone (4), respectively and could be the biotransformed products of the assimilated ketones 3 and 4. Overall current study is confirming identification of 15 constituents for the first time from S. wightii. Antioxidant activities of these extracts and fractions were performed using DPPH, ABTS, FRAP, TAC protocols. Botanicals obtained using n-hexane and methanol has shown remarkable results comparable with commercial antioxidants, BHT and BHA. [ABSTRACT FROM AUTHOR]