1. Clinical course and prognosis of hemodynamically significant congenital heart defects in very low birth weight infants
- Author
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Tae-Gook Jun, Soo In Jeong, Seo Heui Chio, Ji-Hyuk Yang, I Seok Kang, Yun Sil Chang, Pyo Won Park, Ji Eun Kim, Soo Kyoung Park, Sung-Hoon Kim, June Huh, Heung Jae Lee, Hye Soo Yoo, Yoo Jin Jeong, Won Soon Park, and Hyun Ju Seo
- Subjects
Pediatrics ,medicine.medical_specialty ,Prognostic factor ,Periventricular leukomalacia ,business.industry ,Birth weight ,Medical record ,Clinical course ,medicine.disease ,Cardiac surgery ,Low birth weight ,Pediatrics, Perinatology and Child Health ,Medicine ,In patient ,cardiovascular diseases ,medicine.symptom ,business - Abstract
Purpose : This study investigated the clinical course and prognostic factor of very low birth weight infants (VLBWI) with hemodynamically significant congenital heart defects (CHDs). Methods : Medical records of 1,098 VLBWI with birth weight Gr III), and periventricular leukomalacia. Cardiac surgery was performed on 13 patients (39%). Nine patients received staged operations, and 10 patients received early intervention. The overall mortality in patients who had CHD was higher than in the patients who did not have CHD (27% vs. 16%). In patients with CHD, congenital abnormalities or chromosomal disorders were more important factors for increased mortality (86% vs. 11%) than the degree of complexity of CHD (19% vs. 42%). Conclusion : The most important prognostic factors of VLBWI with CHD are the associated congenital abnormalities or chromosomal disorders.
- Published
- 2009
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