1. Progressive Transformation of Germinal Centers Simulating Malignant Axillary Lymphadenopathy in a Breast Cancer Patient on FDG PET/CT.
- Author
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Hod N, Nalbandyan K, Porges T, and Lantsberg S
- Subjects
- Female, Humans, Middle Aged, Fluorodeoxyglucose F18, Positron Emission Tomography Computed Tomography, Lymphatic Metastasis pathology, Lymph Nodes pathology, Radiopharmaceuticals, Breast Neoplasms complications, Breast Neoplasms diagnostic imaging, Breast Neoplasms pathology, Lymphadenopathy diagnostic imaging
- Abstract
Abstract: A 64-year-old woman with breast cancer underwent FDG PET/CT for follow-up. The study revealed highly increased FDG uptake in newly diagnosed enlarged axillary lymph nodes, which were worrisome for malignancy. Histopathology revealed a rarely diagnosed benign disease of progressive transformation of germinal centers mimicking malignant lymphadenopathy. As imaging findings of this entity, which usually involves the axillary and cervical areas, have been reported in very few studies, nuclear medicine physicians should be familiar with this potential "false-positive" FDG uptake representing an interpretative pitfall, especially during evaluation of breast cancer patients., Competing Interests: Conflicts of interest and sources of funding: none declared., (Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.)
- Published
- 2023
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