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Your search keyword '"Barbeau, Emmanuel J."' showing total 6 results
Start Over Author "Barbeau, Emmanuel J." Publisher lippincott williams & wilkins
6 results on '"Barbeau, Emmanuel J."'

4. MR, (18)F-FDG, and (18)F-AV45 PET correlate with AD PSEN1 original phenotype.

Author

Saint-Aubert, Laure, Payoux, Pierre, Hannequin, Didier, Barbeau, Emmanuel J, Campion, Dominique, Delisle, Marie-Bernadette, Tafani, Mathieu, Viallard, Gérard, Péran, Patrice, Puel, Michèle, Chollet, François, Demonet, Jean-François, and Pariente, Jérémie

Abstract

We report the case of a 37-year-old man suffering from insidious visual agnosia and spastic paraparesis due to a PSEN1 mutation. His mother was diagnosed with Alzheimer disease after a biopsy. He was assessed by multimodal neuroimaging, including new in vivo positron emission tomography amyloid imaging (F-AV45). His data were compared with those from healthy participants and patients with sporadic predemential Alzheimer disease. He exhibited posterior cortical thickness reduction, posterior hypometabolism, and increased amyloid ligand uptake in the posterior cortex and the striatum. We show that F-AV45 positron emission tomography allows visualization of the unusual pattern of amyloid deposits that co-localize with cortical atrophy in this genetic form of Alzheimer disease. [ABSTRACT FROM AUTHOR]

Published
2013
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5. MR, 18F-FDG, and 18F-AV45 PET Correlate With AD PSEN1 Original Phenotype.

Author

Saint-Aubert, Laure, Payoux, Pierre, Hannequin, Didier, Barbeau, Emmanuel J., Campion, Dominique, Delisle, Marie-Bernadette, Tafani, Mathieu, Viallard, Gérard, Péran, Patrice, Puel, Michèle, Chollet, François, Demonet, Jean-François, and Pariente, Jérémie

Abstract

The article presents a case study of a 37-year-old man who was admitted to the hospital with complaints of progressive gait disorder followed by cognitive difficulties. His structural magnetic resonance imaging (MRI) scan revealed posterior cortical atrophy on T1 sequence. His thorough analysis revealed a higher bilateral hippocampal AV45 uptake in patient than in patients with Alzheimer's disease.

Published
2013
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