25 results on '"Bould MD"'
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2. Is a new classification of postoperative myocardial infarction justified?
- Author
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Bould MD and Bould, M Dylan
- Published
- 2006
3. Letter to the editor. Predicting failed extubation in critically ill children.
- Author
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Bould MD
- Published
- 2007
- Full Text
- View/download PDF
4. An Evaluation of the Transfer of Skills and Knowledge from Two World Federation of Societies of Anaesthesiologists Fellowship Programs.
- Author
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Bould MD, Cousins JB, Hoang J, Zha Y, Yilma L, Gacii VM, Subramanian B, and Evans FM
- Subjects
- Humans, Societies, Medical, Education, Medical, Graduate, Qualitative Research, Leadership, Health Knowledge, Attitudes, Practice, Mentors, Fellowships and Scholarships, Anesthesiologists education, Anesthesiology education, Clinical Competence, Program Evaluation
- Abstract
Background: Subspecialist training is an important part of developing human resources for health and for some learners, may require taking place in another, higher-resourced country. Despite effective learning of skills and knowledge in a different, more highly resourced context, transfer of these skills and knowledge back to a more poorly resourced context can be a challenge. We aimed to evaluate the transfer of skills and knowledge in 2 World Federation of Societies of Anaesthesiologists (WFSA) fellowship programs., Methods: This qualitative program evaluation study, guided by Guskey's evaluation framework, used in-depth interviews of both faculty and graduates of the 2 fellowship programs. Interviews were conducted remotely, transcribed verbatim, and analyzed using qualitative content and pattern analysis., Results: We interviewed 2 administrators, 10 faculty members, 17 graduated fellows, and 3 graduated fellows now in the role of faculty member in that fellowship. Key themes were barriers and enablers to the transfer of skills, including workplace and staffing, resources, mentorship, the interprofessional team, and leadership. Graduated fellows were able to have an impact on returning home in the areas of practice and service development, research, and teaching., Conclusions: Our study found that the 2 fellowship programs had variable success in the transfer of learned skills and knowledge back to the fellows' "home" institutions. Contextual differences between the fellowship institution and the home institution were the main source of barriers to transfer, and fellows from different countries had diverse needs. Supporting the transfer of knowledge and skills should be an explicit goal of these fellowship programs, and as such, should be considered in the recruitment of fellows, curriculum development, and in how the success of a fellowship is evaluated. Curricula should not just focus on medical knowledge and skills, but also skills in leading change and in education., Competing Interests: Conflicts of Interest: See Disclosures at the end of the article., (Copyright © 2024 International Anesthesia Research Society.)
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- 2024
- Full Text
- View/download PDF
5. Perioperative Anesthesia-Related Complications and Risk Factors in Children: A Cross-Sectional Observation Study in Rwanda.
- Author
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Nizeyimana F, Skelton T, Bould MD, Beach M, and Twagirumugabe T
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- Child, Humans, Infant, Newborn, Cross-Sectional Studies, Intraoperative Complications epidemiology, Postoperative Complications diagnosis, Postoperative Complications epidemiology, Postoperative Complications etiology, Risk Factors, Rwanda epidemiology, Anesthesia adverse effects, Heart Arrest etiology
- Abstract
Background: Despite an increasing awareness of the unmet burden of surgical conditions, information on perioperative complications in children remains limited especially in low-income countries such as Rwanda. The objective of this study was to estimate the prevalence of perioperative anesthesia-related adverse events and to explore potential risk factors associated with them among pediatric surgical patients in public referral hospitals in Rwanda., Methods: Data were collected for all patients under 5 years of age undergoing surgery in 3 public referral hospitals in Rwanda from June to December 2015. Patient and family history, type of surgery, comorbidities, anesthesia technique, intraoperative adverse events and postoperative events in the postanesthesia care unit (PACU) were recorded. The incidence of perioperative adverse events was assessed and associated risk factors analyzed with univariate logistic regression., Results: Of 354 patients enrolled in this study 11 children had a cardiac arrest. Six (1.7%) suffered an intraoperative cardiac arrest, 2 of whom (0.6%) died intraoperatively. In the PACU, 6 (1.8%) suffered a postoperative cardiac arrest, 5 of whom (1.5%) died in the PACU. One child had both an intraoperative cardiac arrest and then a cardiac arrest in PACU but survived. Eighty-nine children (25.1%) had an intraoperative adverse event, whereas 67 (20.6%) had an adverse event in PACU. A review of the cases where cardiac arrest or death occurred indicated that there were significant lapses in the expected standard of care. Age <1 week was associated with cardiac arrest or death., Conclusions: The rate of perioperative complications, including death, for children undergoing surgery in tertiary care hospitals in Rwanda was high. Quality improvement measures are needed to decrease this rate among surgical pediatric patients in this low resource setting., Competing Interests: The authors declare no conflicts of interest., (Copyright © 2023 International Anesthesia Research Society.)
- Published
- 2024
- Full Text
- View/download PDF
6. Burnout Syndrome Among Anesthesia Providers Working in Public Hospitals in Rwanda: A Cross-Sectional Survey.
- Author
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Tuyishime E, McIsaac DI, Mumbwe MC, Ruhato Banguti P, Mvukiyehe JP, Nzarora J, and Bould MD
- Subjects
- Bayes Theorem, Burnout, Psychological, Cross-Sectional Studies, Hospitals, Public, Humans, Rwanda epidemiology, Surveys and Questionnaires, Anesthesia, Burnout, Professional diagnosis, Burnout, Professional epidemiology
- Abstract
Background: Many studies address anesthesia provider burnout in high-income countries; however, there is a paucity of data on burnout for anesthesia providers in low-income countries (LICs). Our objectives were (1) to evaluate the prevalence of burnout among anesthesia providers in Rwandan hospitals and (2) to determine factors associated with burnout among anesthesia providers in Rwandan hospitals., Methods: A questionnaire was sent to selected Rwandan anesthesia providers working in public hospitals. The questionnaire assessed burnout using the Maslach Burnout Inventory Human Services Survey, a validated 22-item survey used to measure burnout among health professionals. Sociodemographic and work-related factors found to be associated with burnout were also assessed using logistic regression in a Bayesian framework to estimate odds ratios (OR) and associated credible intervals (CrIs)., Results: Surveys were distributed to 137 Rwandan anesthesia providers; 99 (72.3%) were returned. Sixty-six (67%) respondents were nonphysician anesthesia providers. Burnout was present in 26 of 99 (26.3%) participants (95% confidence interval [CI], 17.9-36.1). When considering weakly informative priors, we found a 99% probability that not having the right team (OR, 5.36%; 95 CrI, 1.34-23.53) and the frequency of seeing patients with negative outcomes such as death or permanent disability (OR, 9.62; 95% CrI, 2.48-42.84) were associated with burnout., Conclusions: In a cross-sectional survey of anesthesia providers in Rwanda, more than a quarter of respondents met the criteria for burnout. Lacking the right team and seeing negative outcomes were associated with higher burnout rate. These identified factors should be addressed to prevent the negative consequences of burnout, such as poor patient outcomes., Competing Interests: The authors declare no conflicts of interest., (Copyright © 2022 International Anesthesia Research Society.)
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- 2022
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7. Nonphysician Sedation Providers in Africa: What Counts and What Is Being Counted?
- Author
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Asemu YM, Nsereko E, McIsaac DI, and Bould MD
- Subjects
- Africa, Workforce
- Abstract
Competing Interests: Conflicts of Interest: See Disclosures at the end of the article.
- Published
- 2022
- Full Text
- View/download PDF
8. A Prospective, Cohort Study of the Effect of Acute and Chronic Malnutrition on Length of Stay in Children Having Surgery in Rwanda.
- Author
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Seneza C, McIsaac DI, Twagirumugabe T, and Bould MD
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- Child, Cohort Studies, Growth Disorders complications, Growth Disorders epidemiology, Humans, Infant, Length of Stay, Prevalence, Prospective Studies, Rwanda epidemiology, Malnutrition complications, Malnutrition diagnosis, Malnutrition epidemiology, Wasting Syndrome complications, Wasting Syndrome epidemiology
- Abstract
Background: Malnutrition is common in pediatric surgical patients, but there are little data from low-income countries that estimate the association of malnutrition with surgical outcomes. We aimed to determine the prevalence of malnutrition and its association with length of stay (LOS) among pediatric surgical patients in Kigali, Rwanda., Methods: We conducted a prospective observational cohort study. We enrolled surgical patients between 1 month and 15 years of age. We measured the association of acute malnutrition (wasting) and chronic malnutrition (stunting) with postoperative LOS using log-gamma regression to account for the skewed LOS distribution. Adjustment was made for sex, age, elective versus emergency surgery, household income, and American Society of Anesthesiologists (ASA) classification., Results: Of 593 children, 124 children (21.2%) had acute malnutrition (wasting) with 39 (6.6%) severely wasted. A total of 160 (26.9%) children had chronic malnutrition (stunting), with 81 (13.7%) severely stunted. Median (interquartile range [IQR]) LOS after surgery was 2 (1-5) days for children with mild/no wasting, 6 (2.5-12.5) days for children with moderate wasting, and 6 (2-15) days with severe wasting. Median (IQR) LOS after surgery was 2 (1-6) days for children with mild/no stunting, 3 (1-3) days for children with moderate stunting, and 5 (2.3-11.8) days with severe stunting malnutrition. After adjustment for confounders, the moderate wasting was associated with increased LOS, with ratio of means (RoM), 1.6; 95% confidence interval [CI], 1.3-2.0; P < .0001. Severe wasting was not associated with increased LOS (RoM, 1.3; 95% CI, 0.9-1.7; P = .12). Severe, but not moderate, stunting was associated with increased LOS (RoM, 1.9; 1.5-2.4; P < .0001)., Conclusions: Malnutrition is prevalent in >20% of children presenting for surgery and associated with increased LOS after surgery, even after accounting for individual and family-level confounders. Although some aspects of malnutrition may relate to the surgical condition, severe malnutrition may represent a modifiable social risk factor that could be targeted to improve postoperative outcomes and resource use. Severely stunted children should be identified as at risk of having delayed recovery after surgery., Competing Interests: The authors declare no conflicts of interest., (Copyright © 2022 International Anesthesia Research Society.)
- Published
- 2022
- Full Text
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9. Validation of the Lusaka Formula: A Novel Formula for Weight Estimation in Children Presenting for Surgery in Zambia.
- Author
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Phiri H, Foy KE, Bowen L, and Bould MD
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- Adolescent, Age Factors, Child, Child, Preschool, Cross-Sectional Studies, Humans, Infant, Linear Models, Nutritional Status, Prospective Studies, Reproducibility of Results, Zambia, Anesthesiology methods, Anthropometry methods, Body Weight
- Abstract
Background: In children, the use of actual weight or predicted weight from various estimation methods is essential to reduce harm associated with dosing errors. This study aimed to validate the new locally derived Lusaka formula on an independent cohort of children undergoing surgery at the University Teaching Hospital in Lusaka, Zambia, to compare the Lusaka formula's performance to commonly used weight prediction tools and to assess the nutritional status of this population., Methods: The Lusaka formula (weight = [age in months/2] + 3.5 if under 1 year; weight = 2×[age in years] + 7 if older than 1 year) was derived from a previously published data set. We aimed to validate this formula in a new data set. Weights, heights, and ages of 330 children up to 14 years were measured before surgery. Accuracy was examined by comparing the (1) mean percentage error and (2) the percentage of actual weights that fell between 10% and 20% of the estimated weight for the Lusaka formula, and for other existing tools. World Health Organization (WHO) growth charts, mid upper arm circumference (MUAC), and body mass index (BMI) were used to assess nutritional status., Results: The Lusaka formula had similar precision to the Broselow tape: 160 (48.5%) vs 158 (51.6%) children were within 10% of the estimated weight, 241 (73.0%) vs 245 (79.5%) children were within 20% of the estimated weight. The Lusaka formula slightly underestimated weight (mean bias, -0.5 kg) in contrast to all other predictive tools, which overestimated on average. Twenty-two percent of children had moderate or severe chronic malnutrition (stunting) and 4.7% of children had moderate or severe acute malnutrition (wasting)., Conclusions: The Lusaka formula is comparable to, or better than, other age-based weight prediction tools in children presenting for surgery at the University Teaching Hospital in Lusaka, Zambia, and has the advantage that it covers a wider age range than tools with comparable accuracy. In this population, commonly used aged-based prediction tools significantly overestimate weights., Competing Interests: The authors declare no conflicts of interest., (Copyright © 2021 International Anesthesia Research Society.)
- Published
- 2022
- Full Text
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10. Retention and Migration of Rwandan Anesthesiologists: A Qualitative Study.
- Author
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Skelton T, Irakoze A, Bould MD, Przybylak-Brouillard A, Twagirumugabe T, and Livingston P
- Subjects
- Anesthesiologists economics, Developing Countries economics, Female, Humans, Male, Rwanda epidemiology, Workforce economics, Anesthesiologists trends, Career Mobility, Qualitative Research, Surveys and Questionnaires, Workforce trends
- Abstract
Background: Health care professional migration continues to challenge countries where the lack of surgical and anesthesia specialists results in being unable to address the global burden of surgical disease in their populations. Medical migration is particularly damaging to health care systems that are just beginning to scale up capacity building of human resources for health. Anesthesiologists are scarce in low-resource settings. Defining reasons why anesthesiologists leave their country of training through in-depth interviews may provide guidance to policy makers and academic organizations on how to retain valuable health professionals., Methods: There were 24 anesthesiologists eligible to participate in this qualitative interview study, 15 of whom are currently practicing in Rwanda and 9 had left the country. From the eligible group, interviews were conducted with 13 currently practicing in Rwanda and 2 who had left to practice elsewhere. In-depth interviews of approximately 60 minutes were used to define themes influencing retention and migration among anesthesiologists in Rwanda. Interviews were conducted using a semistructured guide and continued until theoretical sufficiency was reached. Thematic analysis was done by 4 members of the research team using open coding to inductively identify themes., Results: Interpretation of results used the framework categorizing themes into push, pull, stick, and stay to describe factors that influence migration, or the potential for migration, of anesthesiologists in Rwanda. While adequate salary is essential to retention of anesthesiologists in Rwanda, other factors such as lack of equipment and medication for safe anesthesia, isolation, and demoralization are strong push factors. Conversely, a rich academic life and optimism for the future encourage anesthesiologists to stay., Conclusions: Our study suggests that better clinical resources and equipment, a more supportive community of practice, and advocacy by mentors and academic partners could encourage more staff anesthesiologists to stay and work in Rwanda.
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- 2020
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11. Anesthesia Capacity in Rural Zambia, Malawi, and Tanzania: The Anesthesiologist's Perspective.
- Author
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Kasole-Zulu T, Ndebea AS, Chikumbanje SS, and Bould MD
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- Humans, Malawi, Tanzania, Zambia, Anesthesia, Anesthesiologists
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- 2020
- Full Text
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12. A Cross-Sectional Survey to Determine the Prevalence of Burnout Syndrome Among Anesthesia Providers in Zambian Hospitals.
- Author
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Mumbwe MC, McIsaac D, Jarman A, and Bould MD
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- Adult, Anesthesiologists trends, Burnout, Psychological diagnosis, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Prevalence, Surveys and Questionnaires, Zambia epidemiology, Anesthesiologists psychology, Burnout, Professional, Burnout, Psychological epidemiology, Burnout, Psychological psychology
- Abstract
Background: Burnout is a psychological syndrome that results from chronic exposure to job stress. It is defined by a triad of emotional exhaustion, depersonalization, and reduced personal accomplishment. In research, mostly from high-income countries, burnout is common in health care professionals, especially in anesthesiologists. Burnout can negatively impact patient safety, the physical and mental health of the anesthetist, and institutional efficiency. However, data on burnout for anesthesia providers in low- and middle-income countries are poorly described. This study sought to determine the prevalence of burnout syndrome among all anesthesia providers (physician and nonphysician) working in Zambian hospitals and to determine which sociodemographic and occupational factors were associated with burnout., Methods: A questionnaire was sent to all Zambian anesthesia providers working in private and public hospitals. The questionnaire assessed burnout using the Maslach Burnout Inventory Human Services Survey, a validated 22-item survey widely used to measure burnout among health professionals. Sociodemographic and occupational factors postulated to be associated with burnout were also assessed., Results: Surveys were distributed to all 184 anesthesia providers in Zambia; 160 were returned. This resulted in a response rate representing 87% of all anesthesia providers in the country. Eighty-six percentage of respondents were nonphysician anesthesia providers. Burnout was present in 51.3% (95% confidence interval [CI], 43.2-59.2) of participants. Logistic regression analysis revealed that "not having the right team to carry out work to an appropriate standard" (odds ratio, 2.91, 95% CI, 1.33-6.39; P = .008), and "being a nonphysician" (odds ratio, 3.4, 95% CI, 1.25-12.34; P = .019) were significantly associated with burnout in this population., Conclusions: In a cross-sectional survey of anesthesia providers in Zambia, >50% of the respondents met the criteria for burnout. The risk was particularly high among nonphysician providers who typically work in isolated rural practice. Efforts to decrease burnout rates through policy and educational initiatives to increase the quantity and quality of training for anesthesia providers should be considered.
- Published
- 2020
- Full Text
- View/download PDF
13. Newborn Resuscitation Skills in Health Care Providers at a Zambian Tertiary Center, and Comparison to World Health Organization Standards.
- Author
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Mistry SC, Lin R, Mumphansha H, Kettley LC, Pearson JA, Akrimi S, Mayne DJ, Hangoma W, and Bould MD
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- Anesthesiologists education, Anesthesiologists standards, Asphyxia Neonatorum diagnosis, Asphyxia Neonatorum mortality, Checklist standards, Cross-Sectional Studies, Healthcare Disparities standards, Humans, Infant, Newborn, Internship and Residency standards, Medical Staff, Hospital education, Midwifery education, Midwifery standards, Nursing Staff, Hospital education, Pediatricians education, Pediatricians standards, Resuscitation adverse effects, Resuscitation mortality, Task Performance and Analysis, Time Factors, Treatment Outcome, Zambia, Asphyxia Neonatorum therapy, Clinical Competence standards, Developing Countries, Medical Staff, Hospital standards, Nursing Staff, Hospital standards, Resuscitation standards, Tertiary Care Centers standards, World Health Organization
- Abstract
Background: Birth asphyxia is a leading cause of early neonatal death. In 2013, 32% of neonatal deaths in Zambia were attributable to birth asphyxia and trauma. Basic, timely interventions are key to improving outcomes. However, data from the World Health Organization suggest that resuscitation is often not initiated, or is conducted suboptimally. Currently, there are little data on the quality of newborn resuscitation in the context of a tertiary center in a lower-middle income country. We aimed to measure the competencies of clinical practitioners responsible for newborn resuscitation., Methods: This observational study was conducted over 5 months in Zambia. Health care professionals were recruited from anesthesia, pediatrics, and midwifery. Newborn skills and knowledge were examined using the following: (1) multiple-choice questions; (2) a ventilation skills test; and (3) 2 low-medium fidelity simulation scenarios. Participant demographics including previous resuscitation training and a self-efficacy rating score were noted. The primary outcome examined performance scores in a simulated scenario, which assessed the care of a newborn that failed to respond to basic interventions. Secondary outcome measures included apnea times after delivery and performance in the other assessments., Results: Seventy-eight participants were enrolled into the study (13 physician anesthesiology residents, 13 pediatric residents, and 52 midwives). A significant difference in interprofessional performance was observed when examining checklist scores for the unresponsive newborn simulated scenario (P = .006). The median (quartiles) checklist score (out of 18) was 14.0 (13.0-14.75) for the anesthesiologists, 11.0 (8.5-12.3) for the pediatricians, and 10.8 (8.3-13.9) for the midwives. A score of 14 or more was required to pass the scenario. There was no significant difference in performance between participants with and without previous newborn resuscitation training (P = .246). The median (quartiles) apnea time after delivery was significantly different between all groups (P = .01) with anesthetic and pediatric residents performing similarly, 61 (37-97) and 63 (42.5-97.5) seconds, respectively. The midwifery participants displayed a significantly longer apnea time, 93.5 (66.3-129) seconds. Self-efficacy rating scores displayed no correlation between confidence level and the primary outcome, Spearman coefficient 0.06 (P = .55)., Conclusions: Newborn resuscitation skills among health care professionals are varied. Midwives lead the majority of deliveries with anesthesiologists and pediatricians only being present at operative or high-risk births. It is therefore common that midwifery practitioners will initiate resuscitation. Despite this, midwives perform poorly when compared to anesthesia and pediatric residents. To address this discrepancy, a multidisciplinary, simulation-based newborn resuscitation program should be considered with continual clinical reenforcement of best practice.
- Published
- 2018
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14. Strengthening the Anesthesia Workforce in Low- and Middle-Income Countries.
- Author
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Kudsk-Iversen S, Shamambo N, and Bould MD
- Subjects
- Anesthetists economics, Anesthetists psychology, Attitude of Health Personnel, Burnout, Professional prevention & control, Burnout, Professional psychology, Career Choice, Clinical Competence, Cooperative Behavior, Health Care Costs, Health Knowledge, Attitudes, Practice, Humans, Interdisciplinary Communication, Needs Assessment, Patient Care Team, Anesthetists supply & distribution, Developing Countries economics, Health Services Accessibility economics, Health Services Needs and Demand economics, Health Workforce economics
- Abstract
The majority of the world's population lacks access to safe, timely, and affordable surgical care. Although there is a health workforce crisis across the board in the poorest countries in the world, anesthesia is disproportionally affected. This article explores some of the key issues that must be tackled to strengthen the anesthesia workforce in low- and lower-middle-income countries. First, we need to increase the overall number of safe anesthesia providers to match a huge burden of disease, particularly in the poorest countries in the world and in remote and rural areas. Through using a task-sharing model, an increase is required in both nonphysician anesthesia providers and anesthesia specialists. Second, there is a need to improve and support the competency of anesthesia providers overall. It is important to include a broad base of knowledge, skills, and attitudes required to manage complex and high-risk patients and to lead improvements in the quality of care. Third, there needs to be a concerted effort to encourage interprofessional skills and the aspects of working and learning together with colleagues in a complex surgical ecosystem. Finally, there has to be a focus on developing a workforce that is resilient to burnout and the challenges of an overwhelming clinical burden and very restricted resources. This is essential for anesthesia providers to stay healthy and effective and necessary to reduce the inevitable loss of human resources through migration and cessation of professional practice. It is vital to realize that all of these issues need to be tackled simultaneously, and none neglected, if a sustainable and scalable solution is to be achieved.
- Published
- 2018
- Full Text
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15. Not If, but How? Using Technology and Task-Sharing to Strengthen the Global Anesthesia Workforce.
- Author
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Drum ET and Bould MD
- Subjects
- Humans, Anesthesia, Dental, Anesthesiology
- Published
- 2017
- Full Text
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16. Challenging Authority During an Emergency-the Effect of a Teaching Intervention.
- Author
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Friedman Z, Perelman V, McLuckie D, Andrews M, Noble LMK, Malavade A, and Bould MD
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- Female, Group Processes, Humans, Intubation, Intratracheal methods, Male, Reproducibility of Results, Communication, Emergencies, Internship and Residency methods, Simulation Training methods, Teaching
- Abstract
Objectives: Previous research has shown that residents were unable to effectively challenge a superior's wrong decision during a crisis situation, a problem that can contribute to preventable mortality. We aimed to assess whether a teaching intervention enabled residents to effectively challenge clearly wrong clinical decisions made by their staff., Subjects and Intervention: Following ethics board approval, second year residents were randomized to a teaching intervention targeting cognitive skills needed to challenge a superior's decision, or a control group receiving general crisis management instruction. Two weeks later, subjects participated in a simulated crisis that presented them with opportunities to challenge clearly wrong decisions in a can't-intubate-can't-ventilate scenario. It was only disclosed that the staff was a confederate during the debriefing. Performances were video recorded and assessed by two raters blinded to group allocation using the modified Advocacy-Inquiry Score., Measurements and Main Results: Fifty residents completed the study. The interrater reliability of the modified Advocacy-Inquiry Scores (intraclass correlation coefficient = 0.87) was excellent. The median (interquartile range) best modified Advocacy-Inquiry Score was significantly better in the intervention group 5.0 (4.50-5.62 [4-6]) than in the control group 3.5 (3.0-4.75 [3-6]) (p < 0.001)., Conclusions: A short targeted teaching intervention was effective in significantly improving residents' ability to challenge a wrong decision by a superior. This suggests that residents are not given the proper tools to challenge authority during a life-threatening crisis situation. This educational gap can have significant implications for patients' safety.
- Published
- 2017
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17. An Analysis of Substandard Propofol Detected in Use in Zambian Anesthesia.
- Author
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Mumphansha H, Nickerson JW, Attaran A, Overton S, Curtis S, Mayer P, and Bould MD
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- Anesthesia, Anesthesiology, Bronchial Spasm chemically induced, Gas Chromatography-Mass Spectrometry, Humans, Hypotension chemically induced, Urticaria chemically induced, Zambia, Anesthetics, Intravenous analysis, Anesthetics, Intravenous standards, Drug Contamination, Propofol analysis, Propofol standards
- Abstract
Background: In early 2015, clinicians throughout Zambia noted a range of unpredictable adverse events after the administration of propofol, including urticaria, bronchospasm, profound hypotension, and most predictably an inadequate depth of anesthesia. Suspecting that the propofol itself may have been substandard, samples were procured and sent for testing., Methods: Three vials from 2 different batches were analyzed using gas chromatography-mass spectrometry methods at the John L. Holmes Mass Spectrometry Facility., Results: Laboratory gas chromatography-mass spectrometry analysis determined that, although all vials contained propofol, its concentration differed between samples and in all cases was well below the stated quantity. Two vials from 1 batch contained only 44% ± 11% and 54% ± 12% of the stated quantity, whereas the third vial from a second batch contained only 57% ± 9%. The analysis found that there were no hexane-soluble impurities in the samples., Conclusions: None of the analyzed vials contained the stated amount of propofol; however, our analysis did not detect additional contaminants that would explain the adverse events reported by clinicians. Our results confirm the presence of substandard propofol in Zambia; however, anecdotal accounts of substandard anesthetic medicines in other countries abound and warrant further investigation to provide estimates of the prevalence and scope of this global problem.
- Published
- 2017
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18. Development of Education and Research in Anesthesia and Intensive Care Medicine at the University Teaching Hospital in Lusaka, Zambia: A Descriptive Observational Study.
- Author
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Janowicz A, Kasole T, Measures E, Langley M, Goma FM, Ismailova F, Kinnear JA, and Bould MD
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- Anesthesiology methods, Blood Transfusion, Data Interpretation, Statistical, Emergency Medicine, Hospitals, University, Humans, Intensive Care Units, Pain Management, Personnel Staffing and Scheduling, Research, Zambia, Anesthesia methods, Anesthesiology education, Critical Care methods, Hospitals, Teaching
- Abstract
Background: Data from 2006 show that the practice of anesthesia at the University Teaching Hospital in Lusaka, Zambia was underdeveloped by international standards. Not only was there inadequate provision of resources related to environment, equipment, and drugs, but also a severe shortage of staff, with no local capability to train future physician anesthetic providers. There was also no research base on which to develop the specialty. This study aimed to evaluate patient care, education and research to determine whether conditions had changed a decade later., Methods: A mix of qualitative data and quantitative data was gathered to inform the current state of anesthesia at the University Teaching Hospital, Lusaka, Zambia. Semistructured interviews were conducted with key staff identified by purposive sampling, including staff who had worked at the hospital throughout 2006 to 2015. Further data detailing conditions in the environment were collected by reviewing relevant departmental and hospital records spanning the study period. All data were analyzed thematically, using the framework described in the 2006 study, which described patient care, education, and research related to anesthetic practice at the hospital., Results: There have been positive developments in most areas of anesthetic practice, with the most striking being implementation of a postgraduate training program for physician anesthesiologists. This has increased physician anesthesia staff in Zambia 6-fold within 4 years, and created an active research stream as part of the program. Standards of monitoring and availability of drugs have improved, and anesthetic activity has expanded out of operating theaters into the rest of the hospital. A considerable increase in the number of cesarean deliveries performed under spinal anesthetic may be a marker for safer anesthetic practice. Anesthesiologists have yet to take responsibility for the management of pain., Conclusions: The establishment of international partnerships to support postgraduate training of physician anesthetists in Zambia has created a significant increase in the number of anesthesia providers and has further developed nearly all aspects of anesthetic practice. The facilitation of the training program by a global health partnership has leveraged high-level support for the project and provided opportunities for North-South and international learning.
- Published
- 2017
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19. The role of simulation in continuing medical education for acute care physicians: a systematic review.
- Author
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Khanduja PK, Bould MD, Naik VN, Hladkowicz E, and Boet S
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- Anesthesiology education, Emergency Medicine education, Humans, Teaching, Critical Care, Education, Medical, Continuing methods, Patient Simulation
- Abstract
Objectives: We systematically reviewed the effectiveness of simulation-based education, targeting independently practicing qualified physicians in acute care specialties. We also describe how simulation is used for performance assessment in this population., Data Sources: Data source included: DataMEDLINE, Embase, Cochrane Database of Systematic Reviews, Cochrane CENTRAL Database of Controlled Trials, and National Health Service Economic Evaluation Database. The last date of search was January 31, 2013., Study Selection: All original research describing simulation-based education for independently practicing physicians in anesthesiology, critical care, and emergency medicine was reviewed., Data Extraction: Data analysis was performed in duplicate with further review by a third author in cases of disagreement until consensus was reached. Data extraction was focused on effectiveness according to Kirkpatrick's model. For simulation-based performance assessment, tool characteristics and sources of validity evidence were also collated., Data Synthesis: Of 39 studies identified, 30 studies focused on the effectiveness of simulation-based education and nine studies evaluated the validity of simulation-based assessment. Thirteen studies (30%) targeted the lower levels of Kirkpatrick's hierarchy with reliance on self-reporting. Simulation was unanimously described as a positive learning experience with perceived impact on clinical practice. Of the 17 remaining studies, 10 used a single group or "no intervention comparison group" design. The majority (n = 17; 44%) were able to demonstrate both immediate and sustained improvements in educational outcomes. Nine studies reported the psychometric properties of simulation-based performance assessment as their sole objective. These predominantly recruited independent practitioners as a convenience sample to establish whether the tool could discriminate between experienced and inexperienced operators and concentrated on a single aspect of validity evidence., Conclusions: Simulation is perceived as a positive learning experience with limited evidence to support improved learning. Future research should focus on the optimal modality and frequency of exposure, quality of assessment tools and on the impact of simulation-based education beyond the individuals toward improved patient care.
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- 2015
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20. Within-team debriefing versus instructor-led debriefing for simulation-based education: a randomized controlled trial.
- Author
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Boet S, Bould MD, Sharma B, Revees S, Naik VN, Triby E, and Grantcharov T
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- Adult, Analysis of Variance, Female, Humans, Male, Operating Rooms, Reproducibility of Results, Anesthesiology education, Clinical Competence, General Surgery education, Interprofessional Relations, Operating Room Nursing education, Patient Care Team organization & administration, Teaching methods
- Abstract
Objective: To compare the effectiveness of an interprofessional within-team debriefing with that of an instructor-led debriefing on team performance during a simulated crisis., Background: Although instructor-led simulation debriefing is considered the "gold standard" in team-based simulation education, cost and logistics are limiting factors for its implementation. Within-team debriefing, led by the individuals of the team itself rather than an external instructor, has the potential to address these limitations., Methods: One hundred twenty subjects were grouped into 40 operating room teams consisting of 1 anesthesia trainee, 1 surgical trainee, and 1 staff circulating operating room nurse. All teams managed a simulated crisis scenario (pretest). Teams were then randomized to either a within-team debriefing group or an instructor-led debriefing group. In the within-team debriefing group, the teams reviewed the video of their scenario by themselves. The teams in the instructor-led debriefing group reviewed their scenario guided by a trained instructor. Immediately after debriefing, all teams managed a different intraoperative crisis scenario (posttest). All sessions were videotaped. Blinded expert examiners used the validated Team Emergency Assessment Measure scale to assess crisis resource management performance of all teams in random order., Result: Team performance significantly improved from pretest to posttest (P = 0.008) regardless of the type of debriefing. There was no significant difference in the degree of improvement between within-team debriefing and instructor-led debriefing (P = 0.52)., Conclusions: Within-team debriefing results in measurable improvements in team performance in simulated crisis scenarios. This form of debriefing may be as effective as instructor-led team debriefing, which could improve resource utilization and feasibility of team-based simulation (NCT01067378).
- Published
- 2013
- Full Text
- View/download PDF
21. Code reader: a novel concept that warrants more research.
- Author
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Power DJ, Boet S, and Bould MD
- Subjects
- Female, Humans, Male, Pregnancy, Emergency Service, Hospital, Evidence-Based Medicine, Heart Arrest therapy, Malignant Hyperthermia drug therapy, Patient Simulation, Reading
- Published
- 2012
- Full Text
- View/download PDF
22. Looking in the mirror: self-debriefing versus instructor debriefing for simulated crises.
- Author
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Boet S, Bould MD, Bruppacher HR, Desjardins F, Chandra DB, and Naik VN
- Subjects
- Female, Humans, Male, Professional Role, Anesthesiology education, Internship and Residency, Knowledge of Results, Psychological, Patient Simulation, Professional Competence, Self-Assessment
- Abstract
Objective: To examine the effectiveness of self-debriefing as compared to instructor debriefing in the change of nontechnical skills performance of anesthesiology residents., Design: Prospective, randomized, controlled study., Setting: A university hospital simulation center., Subjects: : Fifty anesthesiology residents., Interventions: Subjects were instructed in the principles of nontechnical skills for crisis management. Subsequently, each resident participated in a high-fidelity simulated anesthesia crisis scenario (pretest). Participants were randomized to either a video-assisted self-debriefing or instructor debriefing. In the self-debriefing group, subjects reviewed their pretest scenario by themselves, guided by the Anesthetists' Non-Technical Skills scale. The instructor debriefing group reviewed their pretest scenario guided by an expert instructor also using the Anesthetists' Non-Technical Skills scale as a framework. Immediately following their respective debriefings, subjects managed a second simulated crisis (post-test)., Measurements and Main Results: After all data were collected, two blinded experts independently rated videos of all performances in a random order using the Anesthetists' Non-Technical Skills scale. Performance significantly improved from pretest to post-test (p < .01) regardless of the type of debriefing received. There was no significant difference in the degree of improvement between self-debriefing and instructor debriefing (p = .58)., Conclusions: Nontechnical skills for crisis resource management improved with training, as measured by the Anesthetists' Non-Technical Skills scale. Crisis resource management can be taught, with measurable improvements. Effective teaching of nontechnical skills can be achieved through formative self-assessment even when instructors are not available.
- Published
- 2011
- Full Text
- View/download PDF
23. Looking beyond model fidelity.
- Author
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Boet S, Bould MD, and Diemunsch PA
- Subjects
- Bronchoscopy, Cost-Benefit Analysis, Intubation, Intratracheal, Teaching economics, Anesthesiology economics, Anesthesiology education, Clinical Competence economics, Models, Economic
- Published
- 2009
- Full Text
- View/download PDF
24. Teaching lifesaving procedures: the impact of model fidelity on acquisition and transfer of cricothyrotomy skills to performance on cadavers.
- Author
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Friedman Z, You-Ten KE, Bould MD, and Naik V
- Subjects
- Emergencies, Humans, Larynx surgery, Learning, Airway Obstruction surgery, Cadaver, Respiration, Artificial methods, Teaching methods
- Abstract
Background: A decline in emergency surgical airway procedures in recent years has resulted in a decreased exposure to cricothyrotomy. Consequently, residents have very little experience or confidence in performing this intervention. In this study, we compared cricothyrotomy skills acquired on a simple inexpensive model to those learned on a high fidelity simulator using valid evaluation instruments and testing on cadavers., Methods: First and second year anesthesiology residents were recruited. All subjects performed a videotaped pretest cricothyrotomy on cadavers. Subjects were randomized into two groups: The high fidelity group (n = 11) performed two cricothyrotomies on a full-scale simulator with an anatomically accurate larynx. The low fidelity group (n = 11) performed two cricothyrotomies on a low fidelity model constructed from corrugated tubing. Within 2 wk all subjects performed a posttest. Two blinded examiners graded and timed the performances using a checklist and a global rating scale., Results: There was no significant difference in the change from pretest to posttest performance between the model groups as evaluated by all three measures (all: P = NS). Training on both models significantly improved performance on all measures (all: P < 0.001). Inter-rater reliability was strong (checklist: r = 0.90; global rating scale: r = 0.89)., Conclusions: Our study shows that a simple inexpensive model achieved the same effect on objectively rated skill acquisition as did an expensive simulator. The skills acquired on both models transferred effectively to cadavers. Training for this life-saving skill does not need to be limited by simulator accessibility or cost.
- Published
- 2008
- Full Text
- View/download PDF
25. Predicting failed extubation in critically ill children.
- Author
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Bould MD
- Subjects
- Adolescent, Child, Child, Preschool, Female, Humans, Infant, Intensive Care Units, Pediatric, Male, Continuous Positive Airway Pressure instrumentation, Continuous Positive Airway Pressure methods, Respiratory Function Tests, Ventilator Weaning methods
- Published
- 2007
- Full Text
- View/download PDF
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