1. SARS-CoV-2 and Stroke Characteristics
- Author
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Shahjouei, Shima, Tsivgoulis, Georgios, Farahmand, Ghasem, Koza, Eric, Mowla, Ashkan, Vafaei Sadr, Alireza, Kia, Arash, Vaghefi Far, Alaleh, Mondello, Stefania, Cernigliaro, Achille, Ranta, Annemarei, Punter, Martin, Khodadadi, Faezeh, Naderi, Soheil, Sabra, Mirna, Ramezani, Mahtab, Amini Harandi, Ali, Olulana, Oluwaseyi, Chaudhary, Durgesh, Lyoubi, Aicha, Campbell, Bruce C.V., Arenillas, Juan F., Bock, Daniel, Montaner, Joan, Aghayari Sheikh Neshin, Saeideh, Aguiar de Sousa, Diana, Tenser, Matthew S., Aires, Ana, Alfonso, Mercedes de Lera, Alizada, Orkhan, Azevedo, Elsa, Goyal, Nitin, Babaeepour, Zabihollah, Banihashemi, Gelareh, Bonati, Leo H., Cereda, Carlo W., Chang, Jason J., Crnjakovic, Miljenko, De Marchis, Gian Marco, Del Sette, Massimo, Ebrahimzadeh, Seyed Amir, Farhoudi, Mehdi, Gandoglia, Ilaria, Gonçalves, Bruno, Griessenauer, Christoph J., Murat Hanci, Mehmet, Katsanos, Aristeidis H., Krogias, Christos, Leker, Ronen R., Lotman, Lev, Mai, Jeffrey, Male, Shailesh, Malhotra, Konark, Malojcic, Branko, Mesquita, Teresa, Mir Ghasemi, Asadollah, Mohamed Aref, Hany, Mohseni Afshar, Zeinab, Moon, Jusun, Niemelä, Mika, Rezai Jahromi, Behnam, Nolan, Lawrence, Pandhi, Abhi, Park, Jong-Ho, Marto, João Pedro, Purroy, Francisco, Ranji-Burachaloo, Sakineh, Carreira, Nuno Reis, Requena, Manuel, Rubiera, Marta, Sajedi, Seyed Aidin, Sargento-Freitas, João, Sharma, Vijay K., Steiner, Thorsten, Tempro, Kristi, Turc, Guillaume, Ahmadzadeh, Yasaman, Almasi-Dooghaee, Mostafa, Assarzadegan, Farhad, Babazadeh, Arefeh, Baharvahdat, Humain, Cardoso, Fabricio Buchadid, Dev, Apoorva, Ghorbani, Mohammad, Hamidi, Ava, Hasheminejad, Zeynab Sadat, Hojjat-Anasri Komachali, Sahar, Khorvash, Fariborz, Kobeissy, Firas, Mirkarimi, Hamidreza, Mohammadi-Vosough, Elahe, Misra, Debdipto, Noorian, Ali Reza, Nowrouzi-Sohrabi, Peyman, Paybast, Sepideh, Poorsaadat, Leila, Roozbeh, Mehrdad, Sabayan, Behnam, Salehizadeh, Saeideh, Saberi, Alia, Sepehrnia, Mercedeh, Vahabizad, Fahimeh, Yasuda, Thomas Alexandre, Ghabaee, Mojdeh, Rahimian, Nasrin, Harirchian, Mohammad Hossein, Borhani-Haghighi, Afshin, Azarpazhooh, Mahmoud Reza, Arora, Rohan, Ansari, Saeed, Avula, Venkatesh, Li, Jiang, Abedi, Vida, and Zand, Ramin
- Subjects
Adult ,Male ,Risk ,Original Contributions ,International Cooperation ,intracranial hemorrhages ,Clinical and Population Sciences ,Sinus Thrombosis, Intracranial ,Young Adult ,Humans ,Prospective Studies ,Aged ,Ischemic Stroke ,Venous Thrombosis ,neuroimaging ,Geography ,COVID-19 ,cerebrovascular disorders ,Middle Aged ,stroke ,Treatment Outcome ,ComputingMethodologies_DOCUMENTANDTEXTPROCESSING ,Female ,Health Expenditures - Abstract
Supplemental Digital Content is available in the text., Background and Purpose: Stroke is reported as a consequence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in several reports. However, data are sparse regarding the details of these patients in a multinational and large scale. Methods: We conducted a multinational observational study on features of consecutive acute ischemic stroke, intracranial hemorrhage, and cerebral venous or sinus thrombosis among SARS-CoV-2–infected patients. We further investigated the risk of large vessel occlusion, stroke severity as measured by the National Institutes of Health Stroke Scale, and stroke subtype as measured by the TOAST (Trial of ORG 10172 in Acute Stroke Treatment) criteria among patients with acute ischemic stroke. In addition, we explored the neuroimaging findings, features of patients who were asymptomatic for SARS-CoV-2 infection at stroke onset, and the impact of geographic regions and countries’ health expenditure on outcomes. Results: Among the 136 tertiary centers of 32 countries who participated in this study, 71 centers from 17 countries had at least 1 eligible stroke patient. Of 432 patients included, 323 (74.8%) had acute ischemic stroke, 91 (21.1%) intracranial hemorrhage, and 18 (4.2%) cerebral venous or sinus thrombosis. A total of 183 (42.4%) patients were women, 104 (24.1%) patients were
- Published
- 2021