1. Retinopathy in Egyptian patients with sickle cell disease
- Author
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Hassan, Tamer, Badr, Mohamed, Hanna, Diana, Arafa, Mohamed, Elhewala, Ahmed, Dabour, Sherief, Shehata, Saad, and Rahman, Doaa Abdel
- Subjects
Male ,proliferative retinopathy ,genetic structures ,visual acuity ,Adolescent ,Observational Study ,Anemia, Sickle Cell ,eye diseases ,Retina ,Cross-Sectional Studies ,Retinal Diseases ,fluorescein angiography ,Humans ,sickle cell disease ,Egypt ,Female ,ocular complications ,Child ,Tomography, Optical Coherence ,Research Article - Abstract
Sickle cell disease (SCD) is a disorder that causes red blood cells to become sticky and rigid. Sickle cells can block blood flow in small blood vessels depriving the eye of oxygen and cause damage. This is called sickle retinopathy that can progress to severe proliferative sickle cell retinopathy, bleeding into the eye, detachment of the retina or even loss of vision. To assess ocular manifestations and detect frequency of retinopathy in patients with SCD. Cross-sectional study was conducted on 32 patients with SCD. They were 22 males and 10 females with mean age of 12 years. Routine investigations as well as ophthalmological examination including visual acuity, fluorescein angiography and optical coherence tomography were done. We found that 8 patients (25%) suffered from proliferative retinopathy, 10 patients (31%) showed tortuous retinal veins, while 14 patients (44%) were normal. All patients showed macular thinning on optical coherence tomography examination. We concluded that frequency of retinopathy in patients with SCD is more than expected and it was higher in patients who started transfusion at a later age. More attention should be paid for this problem and close observations and follow up is strongly needed.
- Published
- 2021