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Purpose To assess whether corneal parameters and aberrations are affected by accommodation. Setting Optics Department, University of Valencia, Valencia, Spain. Design Prospective cross-sectional study. Methods The Galilei G4 dual Scheimpflug device was used to obtain data on the anterior and posterior axial curvatures, total corneal power (TCP), and corneal pachymetry from 3 corneal zones (central: 0.0 up to 4.0 mm; paracentral or mid: 4.0 up to 7.0 mm; peripheral: 7.0 up to 10.0 mm) in young emmetropic eyes in the unaccommodated and 4 accommodated states (from −1.0 to −4.0 diopters [D] in 1.0 D steps). The 2nd-, 3rd-, and 4th-order aberrations as well as the root mean square (RMS) were also determined for the entire cornea at the same accommodative demands. Results The study evaluated 7 subjects (12 eyes). No significant changes in any measured parameter were found during accommodation for any corneal zone ( P > .05). Statistically significant differences were found in the various corneal zones when it was assumed they were constant with accommodation ( P < .01). A stable linear trend with accommodation was also found for corneal aberrations, although individual variations existed because of the high standard deviation values. Conclusion Different parameters in various zones of the cornea as well as corneal aberrations were stable during accommodation. Financial Disclosure No author has a financial or proprietary interest in any material or method mentioned. [ABSTRACT FROM AUTHOR]