15 results on '"Laino, L."'
Search Results
2. Intravascular Papillary Endothelial Hyperplasia of the Mandible: A Rare Entity.
- Author
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Luigi L, Diana R, Luca F, Pierluigi M, Gregorio L, and Cicciù M
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- Diagnosis, Differential, Endothelial Cells, Humans, Hyperplasia pathology, Mandible pathology, Hemangioendothelioma diagnosis, Hemangioendothelioma pathology, Hemangioendothelioma surgery, Vascular Neoplasms pathology
- Abstract
Abstract: Intravascular papillary endothelial hyperplasia (IPEH) is a lesion characterized by the proliferation of endothelial cells within the lumen of the vessel, it was first described by Masson in 1923.The pathogenesis of Masson's tumor is still unknown, currently the most accredited hypothesis is the reactive 1. Clinically and symptomatologically it can have different presentations, it is, therefore, of fundamental importance to make a correct differential diagnosis. Diagnosis is mainly based on histological criteria. Intravascular papillary endothelial hyperplasia usually occurs in the skin and subcutaneous tissues, less commonly in the skeleton. The present is the fifth case of intravascular papillary endothelial hyperplasia of the mandible., Competing Interests: The authors report no conflicts of interest., (Copyright © 2021 by Mutaz B. Habal, MD.)
- Published
- 2022
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3. Impacted Lower Third Molar Under Inferior Alveolar Canal: Technical Strategy for Minimally Invasive Extraoral Surgical Approach.
- Author
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Laino L, Mariani P, Laino G, Cervino G, and Cicciù M
- Subjects
- Female, Humans, Mandible surgery, Mandibular Nerve, Middle Aged, Minimally Invasive Surgical Procedures, Osteotomy, Tooth Extraction, Molar, Third surgery, Tooth, Impacted surgery
- Abstract
Abstract: Ectopic lower third molar is an uncommon condition, and its etiology remains unclear. The main approach used for its surgical removal is the intraoral one, but there are cases in which this may not be the best option. When the lower third molar is located below the lower alveolar canal or when it is close to the lower edge of the jaw, the most recommended approach is the extraoral one. The critical issues related to the extraoral approach are the possibility of damaging anatomical structures such as marginal mandibular branch of the facial nerve (craniofacial nerve VII), facial artery and vein, and submental artery. This complication can occur during incision and dissection of the superficial layers or during osteotomy with rotating instruments.This paper reports a case of extraction of ectopic lower third molar using a minimally invasive extraoral approach combined with piezoelectric surgery in order to prevent intraoperative injury of anatomical structures., Competing Interests: The authors report no conflicts of interest., (Copyright © 2021 by Mutaz B. Habal, MD.)
- Published
- 2021
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4. Surgical Treatment of Oral Cavity Nodular Fasciitis.
- Author
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Zhurakivska K, Troiano G, Montella M, Ronchi A, Di Stasio D, Cicciù M, and Laino L
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- Adult, Biopsy, Cheek pathology, Diagnosis, Differential, Fasciitis diagnosis, Humans, Male, Mouth Neoplasms complications, Mouth Neoplasms diagnosis, Mouth Neoplasms surgery, Fasciitis etiology, Histiocytoma, Malignant Fibrous complications, Histiocytoma, Malignant Fibrous diagnosis, Histiocytoma, Malignant Fibrous surgery, Mouth Neoplasms pathology
- Abstract
Background: Nodular fascitiis is a myofibroblastic neoplasm of the soft tissue that rarely affects oral cavity. With a broad pattern of presentation, sometimes Nodular Fascitiis can have a rapid growth and appear highly cellular with local aggressiveness on biopsies, thus simulating a sarcoma. The aim of this paper is to present a case of troublesome diagnosis of nodular fascitiis mimicking a Malignant Fibrous Histiocytoma, with the purpose of alert clinicians and pathologists on the difficulties that can be met in the differential diagnosis between these 2 lesions. A 42-year-old male presented an exophytic lesion on the cheek. After the excisional biopsy, histological and immunohistochemical evaluations revealed a picture of doubtful significance. With a careful analysis, the diagnosis of nodular fasciitis was made and the patient was not further treated. At a 3-year follow-up, no recurrence was found. Differential diagnosis within myofibroblastic neoplasm can be a real challenge for both Clinicians and Pathologist. A coordinated team-work is mandatory to avoid clinical malpractice and unnecessarily aggressive treatment.
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- 2020
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5. Surgical Strategies for Multicystic Ameloblastoma.
- Author
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Laino L, Cicciù M, Russo D, and Cervino G
- Subjects
- Biopsy, Fine-Needle, Chin surgery, Dermabrasion, Female, Humans, Mandibular Neoplasms pathology, Microsurgery, Middle Aged, Wound Healing, Ameloblastoma surgery, Mandibular Neoplasms surgery
- Abstract
Ameloblastoma is the second most common odontogenic tumor arising in the maxillary bones. The WHO classified ameloblastoma in: solid/multicystic (SMA); unicystic; peripheral and desmoplastic. A conservative or radical approach may be performed for SMA treatment to achieve total excision of the lesion.In this case report, a 47-year-old woman, presented a deformation of the left mandibular region and paresthesia of the left hemi-labium, at the ortopanoramic x-ray (OPT) a multilocular osteolytic lesion and the rhizalysis of dental elements 3.7, 3.6, 3.5, 3.4 and the inclusion of 3.8 was appreciated; the CT exam showed erosion of the mandibular canal roof and of the vestibular cortex in the mental nerve region. The patient was subjected to the extraction of the elements in rhizalysis and of 3.8 and subsequently to the enucleation of the lesion followed by an extensive peripheral ostectomy performed with a piezoelectric device. The patient underwent to OPT and CT examinations follow-up and after 5 years was subjected to implant surgery, at the same time of the implant's placement, bone biopsies were performed using core drills in order to evaluate the bone histologically. The patient showed complete clinical and radiographic healing; the histological examination demonstrates the formation of lamellar bone.
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- 2020
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6. Solitary Plasmacytoma of the Mandible: Early Diagnosis and Surgical Management.
- Author
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Rullo R, Scalzone P, Laino L, Russo A, Festa VM, Fiorillo L, and Cicciù M
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- Aged, Early Diagnosis, Female, Humans, Mandible, Bone Neoplasms diagnosis, Plasmacytoma diagnosis
- Abstract
Solitary plasmacytoma is an abnormal proliferation of B-lymphoid cells that involves a single bone. It mainly affects the axial skeleton; the jaw localization is a rare condition. The authors present a case of a 70-year-old female patient with a radiolucency of the angle of the mandible later diagnosed as solitary plasmacytoma.
- Published
- 2019
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7. Autism spectrum disorder in a patient with a genomic rearrangement that only involves the EPHA5 gene.
- Author
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Pascolini G, Majore S, Valiante M, Bottillo I, Laino L, Agolini E, Novelli A, Grammatico B, Calvani M, and Grammatico P
- Subjects
- Adolescent, Autistic Disorder genetics, Comparative Genomic Hybridization, Female, Gene Duplication genetics, Genome-Wide Association Study, Genomics, Humans, Intellectual Disability genetics, Italy, Phenotype, Receptor, EphA5 physiology, Autism Spectrum Disorder genetics, Receptor, EphA5 genetics
- Abstract
About one child in 68 is affected by the autism spectrum disorder (ASD), one of the most common neurodevelopmental disorders linked to intellectual disability, especially in males, intellectual disability being diagnosable in about 60-70% of autistic individuals. The biological bases of ASD are not yet fully known, but they are generally considered multifactorial, although many genes and genomic loci have been proposed to be possibly associated with this condition. In this report, we describe the case of a 14-year-old female Italian proband affected by ASD, carrying a novel ~ 270 kb interstitial microduplication, localized at the distal portion of the 4q13.1 region. The rearrangement was inherited from a mild symptomatic father and included a large part of the single EPHA5 gene, a receptor tyrosine kinase involved in the neural development, already indicated to be linked to ASD by previous Genome Wide Association Studies. This imbalance represents, to the best of our knowledge, the smallest duplication identified to date that only impacts the EPHA5 gene. We hypothesize that the duplication of this gene may alter EPHA5 expression and that this may impact the autistic phenotype of the patient.
- Published
- 2019
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8. Multidisciplinary Diagnostic and Surgical Management of Adenocarcinoma Gingival Metastases.
- Author
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Di Stasio D, Montella M, Cozzolino I, Cicciù M, Cervino G, Paparella RS, Serpico R, and Laino L
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- Adenocarcinoma secondary, Adenocarcinoma surgery, Aged, Biopsy, Colonic Neoplasms diagnosis, Colonoscopy, Humans, Male, Mouth Neoplasms surgery, Prognosis, Adenocarcinoma diagnosis, Colonic Neoplasms secondary, Mouth Neoplasms pathology, Oral Surgical Procedures methods
- Abstract
Colon cancer is the third leading cause of cancer-related mortality worldwide and colon cancer metastases in rare sites, such as the oral cavity, lead to a worse prognosis. Oral metastasis is a rare clinical condition and it represents only the 1% among all oral cavity neoplasms. A multidisciplinary approach is recommended to carry out a correct diagnostic procedure that allows distinguishing between metastatic and primitive lesions of the oral cavity. Quick diagnosis and management are fundamental to take an appropriate action as early as possible, as usually the prognosis in patients with oral metastases of colon carcinoma is poor. Aim of this brief clinical report is to underline how the quick diagnosis and management of gingival lesions can be crucial for the correct management of those uncommon oral diseases and for having a better prognosis of the primary cancer.
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- 2018
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9. Postextraction Dental Implant in the Aesthetic Zone, Socket Shield Technique Versus Conventional Protocol.
- Author
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Bramanti E, Norcia A, Cicciù M, Matacena G, Cervino G, Troiano G, Zhurakivska K, and Laino L
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- Humans, Dental Implantation methods, Dental Implants, Esthetics, Dental
- Abstract
The aim of this randomized controlled trial was to evaluate the survival rate, the marginal bone level, and the aesthetic outcome; at 3 years' follow-up, of dental implants placed into a high-esthetic aesthetic zone by comparing 2 techniques of postextraction implant with immediate loading: the socket shied technique and the conventional insertion technique.Several clinical studies suggested that the avulsion of a dental element causes dimensional alterations of both soft and hard tissues at the postextractive site. To increase the aesthetic outcomes, the "socket-shield technique" has been proposed. This method involves maintaining the vestibular root portion and immediate insertion of the dental implant in close proximity to the root.Patients enrolled in this study were randomized to receive a postextraction implant in the aesthetic zone, either with the socket shied technique or with the conventional insertion technique. Implant survival, marginal bone level, and the pink aesthetic score were the outcomes evaluated.Implant survival rate was 100% in both the groups at 3 years. Implants inserted with the socket shield technique showed better values of both marginal bone level and pink aesthetic score (P < 0.05).Although such preliminary results need to be further confirmed, the socket shield technique seems to be a safe surgical technique that allows an implant rehabilitation characterized by better aesthetic outcomes.
- Published
- 2018
- Full Text
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10. Rate of Relapse After Enucleation of Solid/Multicystic Ameloblastoma Followed by Piezoelectric or Conventional Peripheral Ostectomy.
- Author
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Troiano G, Inghingolo A, Serpico R, Ciavarella D, Lo Muzio L, Cervino G, Cicciù M, and Laino L
- Subjects
- Case-Control Studies, Humans, Italy epidemiology, Recurrence, Retrospective Studies, Ameloblastoma epidemiology, Ameloblastoma surgery, Orthopedic Procedures adverse effects, Orthopedic Procedures statistics & numerical data, Piezosurgery adverse effects, Piezosurgery statistics & numerical data
- Abstract
The use of piezo surgery is characterized by a good cutting ability associated with a higher soft tissues respect. Such skills have led to an increment of the use of such systematic in the clinical practice. The aim of this study was to figure out whether the use of piezo surgery may show clinical advantages when enucleation is followed by peripheral ostectomy for the treatment of solid/multicystic ameloblastoma. A retrospective case-control study was performed, including patients treated with piezo surgery or conventional drilling in a single center in Italy. Results of this investigation revealed a lower rate of relapse, at 5 years' follow-up for patients treated with piezo surgery. Although characterized by low power of evidences, the results of this investigation encourage the development of further studies related to the use of piezo surgery for the treatment of solid/multicystic ameloblastoma.
- Published
- 2018
- Full Text
- View/download PDF
11. Tissue Fluorescence Imaging (VELscope) for Quick Non-Invasive Diagnosis in Oral Pathology.
- Author
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Cicciù M, Herford AS, Cervino G, Troiano G, Lauritano F, and Laino L
- Subjects
- Early Detection of Cancer, Female, Humans, Middle Aged, Point-of-Care Systems, Carcinoma, Squamous Cell diagnostic imaging, Mouth Neoplasms diagnostic imaging, Optical Imaging instrumentation
- Abstract
Oral squamous cell carcinoma is the most common form of malignancy of the oral cavity; its incidence is increasing and late-stage presentation is common. It is usually predated by oral premalignant disorders. For this reason, early diagnosis is fundamental to reduce the malignant transformation of oral premalignant disorders and for increase the survival rate for oral cancer. Scraping the surface of the lesion is useful for having cytological features of the investigated tissue. The features of smears of oral premalignant lesions are the keratinization growth (red, orange, brown), the increased nuclear area and so the nuclear hyperchromatism, the nuclear pleomorphism, and the chromatin clumping. All those features are essential for doing the right diagnosis. However, the oral disease should be recognized at the first view by the clinical investigation without touching the lesions avoiding possible alteration in the cells of the tissue. The current standard of incisional biopsy with histology is painful for patients and involves a delay, although histology is completed. The aim of this article is to evaluate the effectiveness of other available tests that are unobtrusive and provide immediate results like the tissue fluorescence imaging.
- Published
- 2017
- Full Text
- View/download PDF
12. Patient Discomfort During and After Surgically Assisted Rapid Maxillary Expansion Under Local Anaesthesia.
- Author
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Laino L, Troiano G, Dioguardi M, Perillo L, Laino G, Lo Muzio L, and Cicciù M
- Subjects
- Adult, Female, Humans, Male, Maxilla surgery, Oral Surgical Procedures, Young Adult, Anesthesia, Local, Molar, Third surgery, Pain Measurement, Pain, Postoperative etiology, Palatal Expansion Technique, Tooth, Impacted surgery
- Abstract
The aim of this study was to evaluate whether surgically assisted rapid maxillary expansion (SARME) could be performed under local anaesthesia and to understand the patient discomfort associated with this protocol. Patient discomfort was compared during and after 2 different types of oral surgical treatments in the same patients. Odontectomies for impacted lower third molar (control) were compared with SARME procedures (test) that were also performed under local anaesthesia. A visual analogic scale was used for each patient to quantify his or her discomfort before and after surgery. A total of 47 patients required 1 of these surgeries and were enrolled in this study. No statistically differences (P >0.05) were observed between the control and test groups. The results of this study suggest that SARME can be safely performed under local anesthesia because the intra- and postoperative discomfort levels were similar to those of other procedures that are typically performed under local anesthesia.
- Published
- 2016
- Full Text
- View/download PDF
13. The Use of Piezosurgery in Genioplasty.
- Author
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Rullo R, Festa VM, Rullo F, Trosino O, Cerone V, Gasparro R, Laino L, and Sammartino G
- Subjects
- Adult, Female, Humans, Incidence, Italy epidemiology, Male, Young Adult, Chin surgery, Genioplasty methods, Piezosurgery methods, Postoperative Complications epidemiology
- Abstract
The aim of this study was to compare the postoperative complications during genioplasty using piezosurgery devices or traditional rotating drills. Forty patients underwent genioplasty to solve their chin anomalies. This study showed that, using piezosurgery, pain and swelling were reduced compared to the traditional technique in the immediate postoperative period of healing (within 15 days). Paresthesia was observed in all patients up to 15th postoperative day, independently of the used surgical technique, but at the sixth postoperative month it was completely absent.
- Published
- 2016
- Full Text
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14. Bone Healing in the Surgical Treatment of Dentigerous Cysts in Critically Ill Patients.
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Laino L, Troiano G, Lo Muzio L, Menditti D, Herford AS, and Cicciù M
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- 2015
- Full Text
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15. Extraoral surgical approach of ectopic mandibular third molar to the lower border of mandible.
- Author
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Laino L, Menditti D, Lo Muzio L, Laino G, Lauritano F, and Cicciù M
- Subjects
- Female, Humans, Male, Middle Aged, Malocclusion surgery, Molar, Third surgery, Tooth Extraction methods, Tooth, Impacted surgery
- Abstract
The surgical removal of impacted lower third molar is an ordinary intervention. The treatment of choice in this pathology is an intraoral or, seldom, extraoral surgical approach. Various surgical procedures have been described to remove ectopic mandibular teeth. The more common technique is an intraoral approach (so named "conservative"), even when the tooth is located in an ectopic area. However, the "intraoral approach" is often related with the difficulty of view, the bleeding of the surgical site, and with the possible lesions of inferior alveolar or lingual nerve. From the other side, a nonconservative surgical approach like "extraoral pathway" may be associated with no aesthetic cutaneous postoperative scar tissue. The aim of those 2 study cases is to highlight the management of infected ectopic third molars located close to the lower border of the mandibular body, underlining the anatomical land markers of the submandibular area. The authors have applied the extraoral pathway using an incision of small size. From our analysis, the treatment of those typical can be managed by using a "mini-skin-incision" (so termed as mini-submandibular approach) respecting the cosmetic expectations of the patients.
- Published
- 2015
- Full Text
- View/download PDF
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