36 results on '"Liu, Limin"'
Search Results
2. Ferroptosis: A therapeutic opportunity of inflammatory bowel disease.
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Ye, Yulin, Liu, Limin, Jing, Yang, Yao, Shuangzhe, Yang, Mo, Dai, Xin, Piao, Meiyu, Xu, Xin, Feng, Zelin, Wang, Xiaoli, Liu, Yifei, Miao, Junming, Gao, Xingjie, Yu, Qingxiang, Cao, Xiaocang, and Pan, Xiangxiang
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- 2024
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3. Hotspots and difficulties of biliary surgery in older patients.
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Zhang, Zongming, Dong, Jiahong, Lin, Fangcai, Wang, Qiusheng, Xu, Zhi, He, Xiaodong, Yang, Shizhong, Li, Youwei, Liu, Limin, Zhang, Chong, Liu, Zhuo, Zhao, Yue, Yang, Haiyan, and Peng, Shuyou
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- 2023
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4. Specific Loss of ABCA1 (ATP-Binding Cassette Transporter A1) Suppresses TCR (T-Cell Receptor) Signaling and Provides Protection Against Atherosclerosis.
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Zhao, Ying, Zhang, Lili, Liu, Limin, Zhou, Xuan, Ding, Fangfang, Yang, Yan, Du, Shiyu, Wang, Hongmin, Van Eck, Miranda, and Wang, Jun
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- 2022
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5. Vitamin D receptor gene polymorphisms and risk of intervertebral disc degeneration
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Xue, Jing, Song, Yueming, Liu, Hao, Liu, Limin, Li, Tao, and Gong, Quan
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Intervertebral Disc Degeneration ,White People ,meta-analysis ,systematic review ,Asian People ,Case-Control Studies ,disc degeneration ,Odds Ratio ,vitamin D receptor ,Humans ,Receptors, Calcitriol ,Genetic Predisposition to Disease ,polymorphisms ,Low Back Pain ,Systematic Review and Meta-Analysis ,Polymorphism, Restriction Fragment Length ,Research Article - Abstract
Background: Numerous studies have investigated the associations between Vitamin D receptor (VDR) gene polymorphisms and risk of intervertebral disc degeneration but the results remain controversial. This study aimed to drive a more precise estimation of association between VDR gene polymorphisms and risk of intervertebral disc degeneration. Methods: PubMed, EMBASE, Cochrane library, Web of Science and China Knowledge Resource Integrated Database for papers on VDR gene polymorphisms and risk of intervertebral disc degeneration were searched. The pooled odds ratios (ORs) with 95% confidence intervals (CIs) were used to assess the strength of association in the homozygote model, heterozygote model, dominant model, recessive model and an additive model. Results: Overall, 23 articles were included in the final meta-analysis. The subgroup analyses by ethnicity showed a significant association of VDR FokI mutation with disc degeneration risk in Caucasians (recessive model, OR with 95%CI 1.301, [1.041, 1.626]; additive model, OR with 95%CI 1.119, [1.006, 1.245]). The results of subgroup analyses by ethnicity showed a significant association of VDR TaqI mutation with disc degeneration risk in Asians but not in Caucasians. There was a significant association between VDR ApaI mutation and risk of disc degeneration and subgroup analyses by ethnicity showed a significant association in Caucasians and in Asians. Conclusions: In summary, VDR FokI polymorphisms was associated with disc degeneration risk among Caucasians but not Asians, VDR TaqI polymorphisms was associated with disc degeneration risk among Asians but not Caucasians, while VDR ApaI polymorphism was associated with disc degeneration risk among Asians and Caucasians.
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- 2021
6. Protective and therapeutic experience of perioperative safety in extremely elderly patients with biliary diseases.
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Zongming Zhang, Yue Zhao, Fangcai Lin, Limin Liu, Chong Zhang, Zhuo Liu, Mingwen Zhu, Baijiang Wan, Hai Deng, Haiyan Yang, Lijun Jiao, Xiyuan Xie, Zhang, Zongming, Zhao, Yue, Lin, Fangcai, Liu, Limin, Zhang, Chong, Liu, Zhuo, Zhu, Mingwen, and Wan, Baijiang
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- 2021
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7. Vitamin D receptor gene polymorphisms and risk of intervertebral disc degeneration: An updated meta-analysis based on 23 studies.
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Jing Xue, Yueming Song, Hao Liu, Limin Liu, Tao Li, Quan Gong, Xue, Jing, Song, Yueming, Liu, Hao, Liu, Limin, Li, Tao, and Gong, Quan
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- 2021
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8. Orbital schwannoma with calcification treated by intracapsular excision: A case report.
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Mingyu Ren, Yixiang Wu, Ruimiao Li, Jingjing Wang, Limin Liu, Yu Gao, Ren, Mingyu, Wu, Yixiang, Li, Ruimiao, Wang, Jingjing, Liu, Limin, and Gao, Yu
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- 2021
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9. Relationship Between Pulmonary Function and Thoracic Morphology in Adolescent Idiopathic Scoliosis: A New Index, the "Apical Vertebra Deviation Ratio", as a Predictive Factor for Pulmonary Function Impairment.
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Zhipeng Deng, Ming Luo, Quan Zhou, Xi Yang, Limin Liu, Yueming Song, Deng, Zhipeng, Luo, Ming, Zhou, Quan, Yang, Xi, Liu, Limin, and Song, Yueming
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- 2021
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10. Posterior hemivertebral resection for upper thoracic congenital scoliosis: be aware of high risk of complications.
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Huang, Yong, Feng, Ganjun, Liu, Limin, Yang, Xi, Song, Yueming, Zhou, Chunguang, Wang, Lei, and Zhou, Zhongjie
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- 2019
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11. Treatment of tuberculous aortic pseudoaneurysm associated with vertebral tuberculosis: A case series and a literature review.
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Jing Xue, Yimin Yao, Limin Liu, Xue, Jing, Yao, Yimin, and Liu, Limin
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- 2018
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12. A case report of congenital scoliosis associated with situs inversus totalis.
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Ce Zhu, Shishu Huang, Chunguang Zhou, Xi Yang, Lei Wang, Tingxian Ling, Limin Liu, Yueming Song, Zhu, Ce, Huang, Shishu, Zhou, Chunguang, Yang, Xi, Wang, Lei, Ling, Tingxian, Liu, Limin, and Song, Yueming
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- 2017
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13. Treatment of type II odontoid fracture with a novel technique: Titanium cable-dragged reduction and cantilever-beam internal fixation.
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Ce Zhu, Lei Wang, Hao Liu, Yueming Song, Limin Liu, Tao Li, Quan Gong, Zhu, Ce, Wang, Lei, Liu, Hao, Song, Yueming, Liu, Limin, Li, Tao, and Gong, Quan
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- 2017
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14. Therapeutic experience of a pancreatic mixed serous neuroendocrine neoplasm invading peripancreatic vessels: A case report.
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Zhang, Zongming, Liu, Limin, Li, Youwei, Liu, Zhuo, Zhang, Chong, Zhao, Yue, Zhu, Mingwen, Wan, Baijiang, Deng, Hai, Xie, Xiyuan, Tian, Kun, Guo, Zhentian, Yang, Haiyan, Liao, Jiahong, Zhu, Hongyan, Liu, Lili, Wang, Man, Ma, Xiaoting, Liu, Tiantian, and Huang, Niuniu
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- 2022
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15. Anterior Retropharyngeal Reduction and Sequential Posterior Fusion for Atlantoaxial Rotatory Fixation With Locked C1-C2 Lateral Facet.
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Chen Qi, Yang Xi, Zhou Chunguang, Liu Limin, Song Yueming, Qi, Chen, Xi, Yang, Chunguang, Zhou, Limin, Liu, and Yueming, Song
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- 2015
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16. β-Elemene inhibits the metastasis of B16F10 melanoma cells by downregulation of the expression of uPA, uPAR, MMP-2, and MMP-9.
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Shi, Hong, Liu, Lei, Liu, Limin, Geng, Jin, Zhou, Yun, and Chen, Lei
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- 2014
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17. Bilateral total knee arthroplasty: Simultaneous or staged? A systematic review and meta-analysis.
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Liu, Limin, Liu, Hongtian, Zhang, Hui, Song, Jingtao, Zhang, Ling, and Muyor., Jose
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- 2019
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18. Abstract 13319: Enhanced Adipose Tissue Inflammation by Deletion of ATP-Binding Cassette Transporter A1 in Adipocytes and Macrophages Reduces the Development of Atherosclerotic Lesions in Male Ldl Receptor Knockout Mice on Western-Type Diet.
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Yang, Jinzhi, Zhang, Lili, Sun, Xiaodong, Liu, Limin, Zhang, Lei, Ding, Fangfang, Wang, Jun, and Zhao, Ying
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- 2018
19. Letter to Indications for CT-Angiography of the Vertebral Arteries after Trauma.
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Qiunan Lyu, Huiliang Yang, Chunguang Zhou, Limin Liu, Yueming Song, Lyu, Qiunan, Yang, Huiliang, Zhou, Chunguang, Liu, Limin, and Song, Yueming
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- 2018
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20. Anterior release internal distraction and posterior spinal fusion for severe and rigid scoliosis.
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Zhou, Chunguang, Liu, Limin, Song, Yueming, Liu, Hao, Li, Tao, Gong, Quan, Zeng, Jiancheng, and Kong, Qingquan
- Abstract
Study Design: Retrospective study.Objective: To report on the results of anterior release, posterior internal distraction (with or without further distraction), and subsequent posterior spinal fusion for severe and rigid scoliosis.Summary Of Background Data: For severe and rigid scoliosis, conventional procedures, such as posterior instrumentation combined with an anterior release, enable limited correction. Posterior vertebral column resection brings better correction but with a high rate of neurological complications or intraoperative neurological events.Methods: A total of 15 patients with severe and rigid scoliosis who underwent anterior release, posterior internal distraction (with or without further distraction), and subsequent posterior spinal fusion were retrospectively reviewed after a minimum follow-up of 2 years. The radiographical parameters were evaluated, and clinical records were reviewed.Results: The average number of anteriorly removed discs was 4.1. Average posterior fusion length comprised 14.3 vertebrae. Overall, internal distraction corrected the mean Cobb angle by 58.1% (from 105.1° to 44.2°) compared with the initial curve magnitude. The mean preoperative scoliosis of 105.1° was corrected to 27.5° (74.3% correction) at the most recent follow-up. The correction rate of the proximal thoracic and thoracolumbar or lumbar curves was 48.1% and 82.1%, respectively. The preoperative thoracic kyphosis of 62.3° was corrected to 33.8° at the most recent follow-up. The preoperative lumbar lordosis of -66.1° was corrected to -46.3° at the most recent follow-up. The mean preoperative coronal imbalance of 0.8 cm improved to 0.5 cm at the most recent follow-up, and sagittal imbalance of 0.3 cm improved to 0.2 cm. Transient dyspnea occurred in one patient after the initial surgery and subsequently resolved. Two patients complained of concave soft-tissue pain after the first distraction. There were no neurological complications.Conclusion: Anterior release, posterior internal distraction, and subsequent posterior spinal fusion provide an effective alternative for severe and rigid scoliosis.Level Of Evidence: 4. [ABSTRACT FROM AUTHOR]- Published
- 2013
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21. Treatment of irreducible old atlantoaxial subluxation with cable-dragged reduction and cantilever beam internal fixation.
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Liu X, Liu H, Li T, Gong Q, Song Y, Liu L, Shi R, Zhao X, Zhang W, Feng G, Wang B, Liu, Xi, Liu, Hao, Li, Tao, Gong, Quan, Song, Yueming, Liu, Limin, Shi, Rui, Zhao, Xiaodan, and Zhang, Wenli
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- 2011
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22. GSNO reductase and β2-adrenergic receptor gene-gene interaction: bronchodilator responsiveness to albuterol.
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Choudhry, Shweta, Que, Loretta G., Yang, Zhonghui, Liu, Limin, Eng, Celeste, Kim, Sung O., Kumar, Gunjan, Thyne, Shannon, Chapela, Rocio, Rodriguez-Santana, Jose R., Rodriguez-Cintron, William, Avila, Pedro C., Stamler, Jonathan S., and Burchard, Esteban G.
- Abstract
Short-acting inhaled β2-agonists such as albuterol are used for bronchodilation and are the mainstay of asthma treatment worldwide. There is significant variation in bronchodilator responsiveness to albuterol not only between individuals but also across racial/ethnic groups. The β2-adrenergic receptor (β2AR) is the target for β2-agonist drugs. The enzyme, S-nitrosoglutathione reductase (GSNOR), which regulates levels of the endogenous bronchodilator S-nitrosoglutathione, has been shown to modulate the response to β2-agonists.We hypothesized that there are pharmacogenetic interactions between GSNOR and β2AR gene variants that are associated with variable response to albuterol.We performed family-based analyses to test for association between GSNOR gene variants and asthma and related phenotypes in 609 Puerto Rican and Mexican families with asthma. In addition, we tested these individuals for pharmacogenetic interaction between GSNOR and β2AR gene variants and responsiveness to albuterol using linear regression. Cell transfection experiments were performed to test the potential effect of the GSNOR gene variants.Among Puerto Ricans, several GSNOR SNPs and a haplotype in the 3′UTR were significantly associated with increased risk for asthma and lower bronchodilator responsiveness (P=0.04-0.007). The GSNOR risk haplotype affects expression of GSNOR mRNA and protein, suggesting a gain of function. Furthermore, gene-gene interaction analysis provided evidence of pharmacogenetic interaction between GSNOR and β2AR gene variants and the response to albuterol in Puerto Rican (P=0.03), Mexican (P=0.15) and combined Puerto Rican and Mexican asthmatics (P=0.003). Specifically, GSNOR+17059∗β2AR+46 genotype combinations (TG+GG∗AG and TG+GG∗GG) were associated with lower bronchodilator response.Genotyping of GSNOR and β2AR genes may be useful in identifying Latino individuals, who might benefit from adjuvant therapy for refractory asthma. [ABSTRACT FROM AUTHOR]
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- 2010
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23. Protective and therapeutic experience of perioperative safety in extremely elderly patients with biliary diseases.
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Zhang Z, Zhao Y, Lin F, Liu L, Zhang C, Liu Z, Zhu M, Wan B, Deng H, Yang H, Jiao L, and Xie X
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- Age Factors, Aged, Aged, 80 and over, Biliary Tract Diseases blood, Biliary Tract Diseases epidemiology, China epidemiology, Comorbidity, Humans, Middle Aged, Retrospective Studies, Biliary Tract Diseases surgery, Perioperative Care statistics & numerical data, Postoperative Complications epidemiology
- Abstract
Competing Interests: The authors have no conflicts of interests to disclose.
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- 2021
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24. Orbital schwannoma with calcification treated by intracapsular excision: A case report.
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Ren M, Wu Y, Li R, Wang J, Liu L, and Gao Y
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- Calcinosis complications, Calcinosis diagnostic imaging, Calcinosis pathology, Female, Humans, Magnetic Resonance Imaging, Middle Aged, Neurilemmoma complications, Neurilemmoma diagnostic imaging, Neurilemmoma pathology, Oculomotor Muscles diagnostic imaging, Oculomotor Muscles pathology, Orbital Neoplasms complications, Orbital Neoplasms diagnostic imaging, Orbital Neoplasms pathology, Calcinosis surgery, Neurilemmoma surgery, Orbital Neoplasms surgery
- Abstract
Rationale: Orbital schwannoma is a relatively rare orbital tumor, and calcification of the lesion is rarely found in the orbit. We report a case of orbital schwannoma which was characterized by calcification in the orbital muscle cone, and was cured by intracapsular excision., Patient Concerns: A 54-year-old female with a complaint of a mass in the left orbit during a magnetic resonance imaging examination and symptom of dizziness 6 months before, presented with painless exophthalmos and vision decline in the left eye., Diagnoses: According to clinical manifestations, imaging examinations and postoperative immunohistochemical examinations, the diagnosis was orbital schwannoma, with calcification in the muscle cone., Interventions: The patient was treated by intracapsular excision of the left orbit. We removed the intracapsular mass and most part of the cyst wall in order to prevent orbital apex syndrome., Outcomes: The diagnosis of schwannoma with calcification was confirmed finally through histological and immunohistochemical exam. The patient was followed up for 28 months and the orbital CT scan showed that there were no significant lesions found in the orbital muscle cone., Lessons: Understanding clinical, imaging diagnostic, and histopathological features of rare orbital schwannoma with calcification will facilitate timely diagnosis and treatment of this condition. The intracapsular excision can help in avoiding complications., Competing Interests: The authors have no conflicts of interests to disclose., (Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.)
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- 2021
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25. Relationship Between Pulmonary Function and Thoracic Morphology in Adolescent Idiopathic Scoliosis: A New Index, the "Apical Vertebra Deviation Ratio", as a Predictive Factor for Pulmonary Function Impairment.
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Deng Z, Luo M, Zhou Q, Yang X, Liu L, and Song Y
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- Adolescent, Female, Humans, Kyphosis physiopathology, Male, Respiratory Function Tests, Retrospective Studies, Spine physiopathology, Vital Capacity, Lung physiopathology, Scoliosis pathology, Scoliosis physiopathology, Thorax pathology
- Abstract
Study Design: A retrospective study., Objective: The aim of this study was to investigate the relationship between thoracic morphology (TM) and pulmonary function (PF) in patients with adolescent idiopathic scoliosis (AIS) and the feasibility of the "apical vertebra deviation ratio (AVDR)" as a predictor of PF impairment., Summary of Background: The PF of AIS is one of the key focuses of clinicians' attention. Early identification of AIS patients who are at risk of developing impaired PF is important for improving patient management., Methods: Preoperative PF and radiographic examination data of 108 patients with thoracic AIS were collected. The following TM data were collected: the costophrenic angle distance (CAD), distance between T1 and mean diaphragm height (T1-diaphragm), T1-T12 height, and AVDR. The correlation coefficient between PF and TM measurements was analyzed, and univariable and multivariable linear regressions were used to determine whether the TM measurements could predict PF., Results: The CAD, T1-diaphragm, and T1-T12 height were significantly positively correlated with forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), vital capacity, and total lung capacity (r = 0.54-0.74, P < 0.01). A linear equation between CAD and pulmonary volume could be established: FVC (L) = -3.46 + CAD (cm) × 0.27 (R2 = 0.54). If T1-T12 height is included, the correlation is further enhanced (R2 = 0.68). There was a significant negative correlation between the AVDR and predicted values of forced vital capacity (FVC%), FEV1%, predicted values of vital capacity, and predicted values of total lung capacity (r = -0.46 to -0.52, P < 0.01). The AVDR could predict the value of each of these variables. One of the linear equations is as follows: FVC% = 110.70-99.73 × AVDR (R2 = 0.272)., Conclusion: The two novel, two-dimensional TM measurements, CAD and AVDR, can be used as moderate to strong predictors of PF outcome in statistical terms. An AVDR >0.2 suggests that the patient may suffer from moderate or severe PF damage.Level of Evidence: 4., (Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.)
- Published
- 2021
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26. Posterior hemivertebral resection for upper thoracic congenital scoliosis: be aware of high risk of complications.
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Huang Y, Feng G, Liu L, Yang X, Song Y, Zhou C, Wang L, and Zhou Z
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- Adolescent, Child, Child, Preschool, Female, Follow-Up Studies, Humans, Intraoperative Neurophysiological Monitoring, Kyphosis diagnostic imaging, Kyphosis surgery, Male, Pedicle Screws, Scoliosis congenital, Scoliosis diagnostic imaging, Spinal Fusion adverse effects, Thoracic Vertebrae diagnostic imaging, Postoperative Complications, Scoliosis surgery, Spinal Fusion methods, Thoracic Vertebrae surgery
- Abstract
The treatment of congenital hemivertebrae in the upper thoracic region is challenging. The objective of this study was to investigate the outcomes of posterior hemivertebral resection for the upper thoracic region. Twenty-one patients diagnosed with upper thoracic congenital scoliosis were included. All of them received hemivertebral resection surgery via the posterior-only approach with at least 2 years of follow-up. The radiographic parameters and Scoliosis Research Society-22 score were analyzed. All the intraoperative and postoperative complications were recorded retrospectively. The segmental main curve was 35.9° before surgery and 7.0° at the last follow-up, with an average correction rate of 80.2%. The total main curve was 44.1° before surgery and 11.6° at the last follow-up, with an average correction rate of 73.9%. The caudal compensatory curve was corrected from 20.2° to 7.1°, with an average correction rate of 64.9%. The segmental kyphosis was corrected from 30.9° to 8.9°, with an average correction rate of 65.5%. The total Scoliosis Research Society-22 score significantly improved in all patients at the last follow-up, mainly resulting from the improvement of the self-image, mental health, and satisfaction domains. The following complications were found: one pedicle fracture, two malpositioned screws, one transient neurologic deficit, one implant failure, and four postoperative curve progressions. Although good radiographic deformity correction and clinical results were achieved after surgery, the incidence rate of complications was high at 42.9%; great care should be taken to prevent them, especially for postoperative curve progression (19.0%).
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- 2019
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27. Therapeutic experience of severe and recurrent secondary hyperparathyroidism in a patient on hemodialysis for 18 years: A case report.
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Zhu M, Zhang Z, Lin F, Miao J, Wang P, Zhang C, Yu H, Deng H, Liu Z, Liu L, Wan B, Yang H, Song M, Zhao Y, Jiang N, Zhang Z, Zhang Z, and Pan L
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- Female, Humans, Kidney Failure, Chronic complications, Kidney Failure, Chronic therapy, Middle Aged, Parathyroid Glands transplantation, Recurrence, Retrospective Studies, Time Factors, Transplantation, Autologous, Hyperparathyroidism, Secondary surgery, Parathyroidectomy methods, Renal Dialysis adverse effects
- Abstract
Introduction: For patients with refractory secondary hyperparathyroidism (SHPT), parathyroidectomy (PTX) has received increasing attention. However, evidence-based medicine shows that there is still controversy regarding surgical methods, efficacy, and safety. We retrospectively analyzed the process of diagnosis and treatment in one patient with severe SHPT and long-term chronic renal failure (CRF), so as to further improve the therapeutic effect., Case Presentation: A 61-year-old female with SHPT and CRF manifested as no urine for 18 years, underwent PTX 4 times since September 2010, with satisfactory final recovery. The first operation involved resection of 3 parathyroid glands in the normal position; the second operation involved removal of an ectopic parathyroid gland, combined with parathyroid gland autotransplantation; the third operation was performed to resect suspected recurrent parathyroid gland; the fourth operation involved partial excision of the autotransplanted parathyroid glands., Conclusion: Accurate preoperative localized diagnosis and optimal surgical approach play key roles in the prevention and treatment of SHPT; postoperative recurrence of SHPT caused by ectopic or autotransplanted parathyroid gland should receive more attention.
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- 2018
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28. Treatment of tuberculous aortic pseudoaneurysm associated with vertebral tuberculosis: A case series and a literature review.
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Xue J, Yao Y, and Liu L
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- Adult, Combined Modality Therapy methods, Female, Humans, Magnetic Resonance Imaging methods, Male, Middle Aged, Tomography, X-Ray Computed methods, Treatment Outcome, Aneurysm, False diagnosis, Aneurysm, False etiology, Aneurysm, False physiopathology, Aneurysm, False surgery, Antitubercular Agents therapeutic use, Aortitis diagnosis, Aortitis etiology, Aortitis therapy, Spinal Fusion methods, Thoracic Vertebrae microbiology, Thoracic Vertebrae pathology, Tuberculosis, Cardiovascular complications, Tuberculosis, Cardiovascular diagnosis, Tuberculosis, Spinal diagnosis, Tuberculosis, Spinal drug therapy, Tuberculosis, Spinal physiopathology, Tuberculosis, Spinal surgery, Vascular Surgical Procedures methods
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Rationale: Tuberculous aortic pseudoaneurysm associated with vertebral tuberculosis is a rare disease but with very high mortality. We review the literature and find 19 reports with 22 patients. Here we report three cases with vertebral tuberculosis, who also have tuberculous pseudoaneurysm of the aorta. These patients were treated by different methods. We try to analyze the epidemiology, pathogenesis, presentation, and management of this disease to find the best treatment., Patient Concerns: The patients presented with different symptoms such as pain (chest, abdominal or back), fever, blood volume reduction or hemorrhagic shock symptoms. Large mass also could be observed by imaging. In addition to clinical manifestations, enhanced computed tomography or magnetic resonance imaging could also help the diagnosis of this disease., Diagnoses: Tuberculous aortic pseudoaneurysm associated with vertebral tuberculosis., Interventions: Three patients were treated with anti-tuberculosis(TB) drugs or combined with different sequences surgical treatment: Case 1 refused to receive pseudoaneurysm surgery and only had anti-TB drug treatment; Case 2 received thoracic spinal surgery first; Case 3 received endovascular stent grafting., Outcomes: Two patients (case 1 and case 2) who refused to undergo aneurysm surgery died. The last patient (case 3) underwent endovascular repair and antibiotic therapy for tuberculosis, and the postoperative course was uneventful; the patient recovered and survived., Lessons: Once the diagnosis of tuberculous pseudoaneurysm is confirmed, surgical treatment should be provided immediately combined with anti-tuberculosis drugs. The aim of the treatment is to save lives, prevent relapse, and facilitate the return to normal life, regardless of the size of the pseudoaneurysm. The pseudoaneurysm should be treated first to prevent aneurysm rupture before the vertebral tuberculosis surgery.
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- 2018
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29. TO THE EDITOR.
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Lyu Q, Yang H, Zhou C, Liu L, and Song Y
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- 2018
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30. A case report of congenital scoliosis associated with situs inversus totalis.
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Zhu C, Huang S, Zhou C, Yang X, Wang L, Ling T, Liu L, and Song Y
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- Abnormalities, Multiple, Child, Female, Humans, Scoliosis congenital, Scoliosis surgery, Situs Inversus
- Abstract
Rationale: Situs inversus totalis is a rare anomaly disease in which the organs in the chest and abdomen are positioned in a mirror image reversal of normal positions. Although this has been confirmed to be associated with spinal abnormalities, reports about situs inversus totalis with congenital scoliosis remain limited., Patient Concerns: We present a 9-year-old girl having congenital scoliosis associated with situs inversus totalis., Diagnoses: She also had other associated anomalies: ventricular septal defect, mild restrictive ventilatory dysfunction, hydronephrosis, and syringomyelia. Her preoperative Cobb angle (T11-L3) was 78°., Interventions: She received single growing rods treatment and subsequent posterior spinal fusion correction surgery for her scoliosis., Outcomes: The coronal Cobb angle of the main curve was corrected to 20° postoperatively and no obvious loss of spinal corrective angle was identified 1 year after the correction surgery., Lessons: Growing rods technique could be a safe and effective alternative for the treatment of scoliosis associated with situs inversus totalis. In the correction of left-sided lumbar curve of this kind of patients, the risks of aorta impingements should not be neglected when placing pedicle screws on the concave sides., (Copyright © 2017 The Authors. Published by Wolters Kluwer Health, Inc. All rights reserved.)
- Published
- 2017
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31. Treatment of type II odontoid fracture with a novel technique: Titanium cable-dragged reduction and cantilever-beam internal fixation.
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Zhu C, Wang L, Liu H, Song Y, Liu L, Li T, and Gong Q
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- Adult, Bone Wires, Closed Fracture Reduction methods, Female, Fracture Fixation, Internal methods, Fracture Healing, Humans, Male, Middle Aged, Neck Pain etiology, Neck Pain surgery, Odontoid Process surgery, Pain Measurement, Retrospective Studies, Salvage Therapy methods, Titanium, Treatment Outcome, Young Adult, Closed Fracture Reduction instrumentation, Fracture Fixation, Internal instrumentation, Odontoid Process injuries, Salvage Therapy instrumentation, Spinal Fractures surgery
- Abstract
Surgical methods for type II odontoid fracture can be classified into 2 main groups: anterior or posterior approach. A more effective way to achieve bone fusion with the lowest possible surgical risk is needed. Therefore, the aim of our study was to describe and evaluate a novel technique, cable-dragged reduction/cantilever beam internal fixation for the treatment of type II odontoid fracture.This was a retrospective study enrolled 34 patients underwent posterior cable-dragged reduction/cantilever-beam internal fixation surgery. Medical records, rates of reduction, the location of the instrumentation and fracture healing during follow-up were analyzed. Once fracture healing was obtained, instrumentation was removed. Neck pain (scored using a visual analog scale [VAS]), neck stiffness, patient satisfaction, and neck disability index (NDI) were recorded before and after removing the instrumentation during follow-up.The mean duration of follow up was 22.8 ± 5.3 months. There was no iatrogenic damage to nerves or blood vessels. Radiographic evaluation showed complete reduction in the 20 patients with fracture displacement and satisfactory fracture healing in all 34 cases. Titanium cable breakage was observed in 4 patients after fracture healing. After removal of instrumentation, significant improvements were seen in neck-pain VAS score, neck stiffness, patient satisfaction, and NDI (all P < .01).Posterior cable-dragged reduction/cantilever-beam internal fixation was an optimal salvage maneuver to conventional surgical methods such as anterior screw fixation and C1-C2 screw-rod system. The operative difficulty and incidence of nerve and vascular injury were reduced. Its major disadvantage is the exposure and screw-setting at C3, which is left intact in traditional surgery, and it is suitable only for patients with intact C1 posterior arches.
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- 2017
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32. Pre- and postoperative spinopelvic sagittal balance in adolescent patients with lenke type 5 idiopathic scoliosis.
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Yang X, Liu L, Song Y, Zhou C, Zhou Z, Wang L, and Wang L
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- Adolescent, Female, Humans, Lordosis diagnostic imaging, Lordosis surgery, Lumbar Vertebrae surgery, Male, Postoperative Period, Postural Balance, Preoperative Period, Radiography, Scoliosis surgery, Thoracic Vertebrae surgery, Treatment Outcome, Lumbar Vertebrae diagnostic imaging, Pelvis diagnostic imaging, Scoliosis diagnostic imaging, Spinal Fusion, Thoracic Vertebrae diagnostic imaging
- Abstract
Study Design: A retrospective study., Objective: To investigate the preoperative spinopelvic sagittal alignment in Lenke 5 patients with adolescent idiopathic scoliosis (AIS), and analyze how it alters after posterior correction., Summary of Background Data: The structural thoracolumbar or lumbar curve may change the local sagittal alignment thereby altering the sagittal balance in Lenke 5 patients with AIS. However, few studies have evaluated the spinopelvic sagittal alignment before and after the surgery in these patients., Methods: Forty-eight Lenke 5 patients with AIS who underwent posterior correction and fusion were included in this study. Preoperative and postoperative radiographs were reviewed measuring both the coronal and sagittal parameters. Three pelvic sagittal states (anteverted, normal, or retroverted) were evaluated according to the magnitude relationship of individual pelvic tilt with pelvic incidence (PI). Both the coronal and sagittal parameters between different pelvic sagittal states were compared. The alterations of these parameters by surgery would also be analyzed., Results: The mean follow-up was 1.8 years. Preoperatively, the mean PI was 44.3° with a pelvic tilt of 4.1°. There was 48% patients showing the anteverted pelvis, whereas the remaining 52% showing normal. The patients with anteverted pelvis showed a smaller PI and more distal lower end vertebra than normal pelvis ones. Logistic regression analysis revealed PI (odds ratio [OR] = 0.62, P = 0.024) and lower end vertebra (OR = 2.1, P = 0.037) were significantly associated with the risk of developing anteverted pelvis. The pelvic tilt was significantly increased and 61% of patients with preoperative anteverted pelvis had recovered. Logistic regression analysis revealed PI (OR = 0.7, P = 0.034) and lower instrumented vertebra (OR = 6.5, P = 0.002) were significantly associated with the risk of postoperative uncovered of anteverted pelvis., Conclusion: Anteverted pelvis appears in almost half of Lenke 5 patients with AIS, especially in who have smaller PI or distal lower end vertebra. The abnormal pelvic sagittal state will be generally corrected by posterior correction surgery except for patients with a PI less than 39° or a lower instrumented vertebra that extends to L5.
- Published
- 2015
- Full Text
- View/download PDF
33. Anterior decompression and nonstructural bone grafting and posterior fixation for cervical facet dislocation with traumatic disc herniation.
- Author
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Feng G, Hong Y, Li L, Liu H, Pei F, Song Y, Huang F, Tu C, Li T, Gong Q, Liu L, Zeng J, Kong Q, and Gupte M
- Subjects
- Adolescent, Adult, Biomechanical Phenomena, Cervical Vertebrae diagnostic imaging, Cervical Vertebrae injuries, Cervical Vertebrae physiopathology, Diskectomy, Female, Humans, Intervertebral Disc Displacement diagnostic imaging, Intervertebral Disc Displacement physiopathology, Joint Dislocations diagnostic imaging, Joint Dislocations physiopathology, Kyphosis surgery, Magnetic Resonance Imaging, Male, Middle Aged, Radiography, Spinal Injuries diagnostic imaging, Spinal Injuries physiopathology, Time Factors, Treatment Outcome, Young Adult, Zygapophyseal Joint injuries, Zygapophyseal Joint physiopathology, Bone Transplantation adverse effects, Cervical Vertebrae surgery, Decompression, Surgical adverse effects, Ilium transplantation, Intervertebral Disc Displacement surgery, Joint Dislocations surgery, Spinal Fusion adverse effects, Spinal Injuries surgery, Zygapophyseal Joint surgery
- Abstract
Study Design: A series study of patients with lower cervical facet dislocation accompanied by traumatic disc herniation treated with anterior decompression and nonstructural bone grafting and posterior fixation., Objective: To describe a surgical technique of anterior decompression and nonstructural bone grafting and posterior fixation and its clinical outcome in a group of patients with lower cervical facet dislocation accompanied by traumatic disc herniation., Summary of Background Data: The optimal treatment for lower cervical facet dislocation with a prolapsed disc is still controversial., Methods: After discectomy and endplate preparation, a layer of morselized cancellous bone grafts from the iliac crest was placed in the interspace, and held in appropriate sagittal position by 2 layers of gelatin sponge and carefully sutured longus colli muscle. The anterior wound was then closed. The posterior elements were exposed and the reduction was performed. Fluoroscopy was used during reduction maneuver to ensure that the graft was still in the appropriate position. A posterior fusion was performed and the posterior wound was closed., Results: Between January 2006 and February 2010, 21 patients with cervical facet dislocation accompanied by traumatic disc herniation (13 unilateral dislocations and 8 bilateral dislocations) were recruited for this study. All the patients completed at least 1-year follow-up. Average follow-up duration was 29 ± 3.5 months. Average Frankel scales were significantly improved at the end of follow-up, visual analogue scale decreased from 7.8 ± 1.2 before the operation to less than 1.6 ± 0.5 (P < 0.05) 6 months later. Kyposis was corrected from 17.7° ± 6.3° to 6.5° ± 4.1° (P < 0.05) and remained at 5.9° ± 4.2° (P > 0.05) 1 year later. The average subsidence of bone graft was 1.28 ± 0.16 mm at 12 months after the operation and remained 1.34 ± 0.20 mm at 36 months after the operation. All patients had consolidation of both anterior and posterior fusions. No cases of instrument failure occurred and no complications were attributed to the use of this technique., Conclusion: Although further study based on injury types as well as long-term follow-up is still needed, anterior decompression and nonstructural bone grafting and posterior fixation provides a promising surgical option for treating cervical facet dislocation with traumatic disc herniation.
- Published
- 2012
- Full Text
- View/download PDF
34. Effect of the decompressive extent on the magnitude of the spinal cord shift after expansive open-door laminoplasty.
- Author
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Kong Q, Zhang L, Liu L, Li T, Gong Q, Zeng J, Song Y, Liu H, Wang S, Sun Y, Zhang F, Li M, and Chen Z
- Subjects
- Adult, Aged, Aged, 80 and over, Analysis of Variance, Cervical Vertebrae pathology, Cervical Vertebrae physiopathology, China, Decompression, Surgical adverse effects, Female, Humans, Intervertebral Disc Displacement pathology, Intervertebral Disc Displacement physiopathology, Linear Models, Lordosis pathology, Lordosis physiopathology, Magnetic Resonance Imaging, Male, Middle Aged, Neurologic Examination, Nonlinear Dynamics, Ossification of Posterior Longitudinal Ligament pathology, Ossification of Posterior Longitudinal Ligament physiopathology, Recovery of Function, Retrospective Studies, Spinal Cord pathology, Spinal Cord physiopathology, Spondylosis pathology, Spondylosis physiopathology, Subarachnoid Space pathology, Time Factors, Treatment Outcome, Cervical Vertebrae surgery, Decompression, Surgical methods, Intervertebral Disc Displacement surgery, Lordosis surgery, Orthopedic Procedures adverse effects, Ossification of Posterior Longitudinal Ligament surgery, Spinal Cord surgery, Spondylosis surgery
- Abstract
Study Design: A retrospective study to analyze the effect of decompressive extent on the posterior shift of spinal cord after expansive open-door laminoplasty (ELAP)., Objective: To investigate the effect of decompressive extent on cord shift distance after ELAP, and determine the morphologic limitations of posterior approach when the cervical alignment is lordotic or straight., Summary of Background Data: It is still controversial on the effect of space available for spinal cord at the level cephalad to the decompression with cord shift. Moreover, there is less understanding regarding the significance of decompressive extent of laminoplasty in relation to spinal cord shift and clinical outcome., Methods: Preoperative and postoperative MRIs of 76 patients with a straight or lordotic cervical spine who had undergone cervical laminoplasty were reviewed and evaluated retrospectively. Radiographic parameters including cervical sagittal alignment, space available at the level cephalad, the thickness of compressive mass, and the average anterior subarachnoid space were measured. Laminoplasty was performed from C1 to C7 in 11 cases (CI group), C2 to C7 in 30 cases (CII group), and C3 to C7 in 35 cases (CIII group). According to whether the anterior indirect decompression was adequate or not, CII and CIII groups were further divided into two subgroups, the noncontact group in which the spinal cord was completely separated from the anterior compressive mass after laminoplasty, and the contact group in which there was residual cord compression after laminoplasty. The recovery rate that based on the Japanese Orthopedic Association score was calculated for each patient., Results: There were statistically significant differences in the average anterior subarachnoid space among CI, CII, and CIII groups (P < 0.05);the average anterior subarachnoid space was the largest in CI group, and the smallest in CIII group. The space available at the level cephalad had strong sigmoidal correlation with cord postoperative shift in CIII group (R = 0.91). A higher neurologic recovery rate (69% ± 20% vs. 29% ± 11%; P < 0.05) in the noncontact group after surgery than in the contact group, with a similar follow-up period., Conclusion: The posterior decompression extent is a main factor affecting cord shift distance after laminoplasty in the context of a straightened or lordotic cervical curvature. The space available at the levels cephalad is a key factor to predict cord shift distance in laminoplasty from C3 to C7. Neurologic recovery rate after ELAP is affected by whether the anterior indirect decompression was adequate or not.
- Published
- 2011
- Full Text
- View/download PDF
35. Anterior single segmental decompression and fixation for Denis B type thoracolumbar burst fracture with neurological deficiency: thirty-four cases with average twenty-six month follow-up.
- Author
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Shi R, Liu H, Zhao X, Liu X, Gong Q, Li T, Liu L, Zeng J, and Song Y
- Subjects
- Adult, Female, Follow-Up Studies, Humans, Male, Middle Aged, Nervous System Diseases complications, Spinal Fractures complications, Time Factors, Treatment Outcome, Young Adult, Decompression, Surgical methods, Fracture Fixation, Internal methods, Lumbar Vertebrae injuries, Spinal Fractures surgery, Thoracic Vertebrae injuries
- Abstract
Study Design: A series study of neurologically deficient patients with Denis B type thoracolumbar burst fractures treated with anterior single segmental decompression and fixation (ASSDF)., Objective: To describe a surgical technique of ASSDF and its clinical outcome in a group of neurologically deficient patients with Denis B type thoracolumbar burst fractures., Summary of Background Data: The optimal treatment for thoracolumbar burst fractures is still controversial., Methods: The canals of selected patients were fully decompressed with partial dissection on fractured vertebral body. Single segmental fusion was achieved with grafting and fixation. Clinical evaluation (including Frankel scales and visual analogue scale) and radiologic assessments (including the measurements of the kyphosis Cobb angle, adjacent superior, inferior intervertebral disc height, and vertebral canal sagittal diameter on radiograph film and computer tomography scans) were performed before the operation and at 3-day, 6-month, 1-, 2-, and 3-year intervals after the operation., Results: Between June 2006 and May 2008, 37 patients with Denis B type thoracolumbar burst fractures were recruited for study. Thirty-four patients with successful ASSDF accomplished a 1-year follow-up. Average follow-up duration was 26 ± 9.2 months. The average operation time and blood loss were 173 ± 26 minutes and 445.6 ± 164.4 mL, respectively. Average Frankel scales were significantly improved at the end of follow-up. visual analogue scale decreased from 7.2 ± 0.8 before operation to less than 1.7 ± 0.7 (P < 0.05) 6 months later. The vertebral canal sagittal diameter was enlarged from an average of 5.9 ± 1.2 mm to 16.2 ± 1.0 mm (P < 0.01). The canal stenosis index also improved, from 36.0% to 99.1%. Kyphosis was corrected from 21.5° ± 6.1° to 7.3° ± 3.2° (P < 0.05) and remained at 8.2° ± 3.6° (P > 0.05) 1 year later. Adjacent disc heights remained constant. No serious complications or fixation failures were observed during follow-up., Conclusion: ASSDF provides a novel and effective surgical option for treating Denis B type fracture with neurologic deficiency.
- Published
- 2011
- Full Text
- View/download PDF
36. GSNO reductase and beta2-adrenergic receptor gene-gene interaction: bronchodilator responsiveness to albuterol.
- Author
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Choudhry S, Que LG, Yang Z, Liu L, Eng C, Kim SO, Kumar G, Thyne S, Chapela R, Rodriguez-Santana JR, Rodriguez-Cintron W, Avila PC, Stamler JS, and Burchard EG
- Subjects
- Albuterol administration & dosage, Aldehyde Oxidoreductases, Asthma genetics, Asthma physiopathology, Bronchodilator Agents administration & dosage, Drug Interactions genetics, Genes, Genotype, Haplotypes, Hispanic or Latino genetics, Humans, Linear Models, Mexican Americans genetics, Mexico, Oxidoreductases genetics, Oxidoreductases pharmacology, Polymorphism, Single Nucleotide, S-Nitrosoglutathione pharmacology, S-Nitrosoglutathione therapeutic use, Albuterol pharmacology, Albuterol therapeutic use, Asthma drug therapy, Bronchodilator Agents pharmacology, Bronchodilator Agents therapeutic use
- Abstract
Background: Short-acting inhaled beta2-agonists such as albuterol are used for bronchodilation and are the mainstay of asthma treatment worldwide. There is significant variation in bronchodilator responsiveness to albuterol not only between individuals but also across racial/ethnic groups. The beta2-adrenergic receptor (beta2AR) is the target for beta2-agonist drugs. The enzyme, S-nitrosoglutathione reductase (GSNOR), which regulates levels of the endogenous bronchodilator S-nitrosoglutathione, has been shown to modulate the response to beta2-agonists., Objective: We hypothesized that there are pharmacogenetic interactions between GSNOR and beta2AR gene variants that are associated with variable response to albuterol., Methods: We performed family-based analyses to test for association between GSNOR gene variants and asthma and related phenotypes in 609 Puerto Rican and Mexican families with asthma. In addition, we tested these individuals for pharmacogenetic interaction between GSNOR and beta2AR gene variants and responsiveness to albuterol using linear regression. Cell transfection experiments were performed to test the potential effect of the GSNOR gene variants., Results: Among Puerto Ricans, several GSNOR SNPs and a haplotype in the 3'UTR were significantly associated with increased risk for asthma and lower bronchodilator responsiveness (P=0.04-0.007). The GSNOR risk haplotype affects expression of GSNOR mRNA and protein, suggesting a gain of function. Furthermore, gene-gene interaction analysis provided evidence of pharmacogenetic interaction between GSNOR and beta2AR gene variants and the response to albuterol in Puerto Rican (P=0.03), Mexican (P=0.15) and combined Puerto Rican and Mexican asthmatics (P=0.003). Specifically, GSNOR+17059*beta2AR+46 genotype combinations (TG+GG*AG and TG+GG*GG) were associated with lower bronchodilator response., Conclusion: Genotyping of GSNOR and beta2AR genes may be useful in identifying Latino individuals, who might benefit from adjuvant therapy for refractory asthma.
- Published
- 2010
- Full Text
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