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31 results on '"Restrepo, Lucas"'

3. Los Angeles Motor Scale to Identify Large Vessel Occlusion: Prehospital Validation and Comparison With Other Screens.

Author

Noorian, Ali Reza, Sanossian, Nerses, Shkirkova, Kristina, Liebeskind, David S., Eckstein, Marc, Stratton, Samuel J., Pratt, Franklin D., Conwit, Robin, Chatfield, Fiona, Sharma, Latisha K., Restrepo, Lucas, Valdes-Sueiras, Miguel, Kim-Tenser, May, Starkman, Sidney, Saver, Jeffrey L., and FAST-MAG Trial Investigators and Coordinators

Published
2018
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4. Paramedic Initiation of Neuroprotective Agent Infusions: Successful Achievement of Target Blood Levels and Attained Level Effect on Clinical Outcomes in the FAST-MAG Pivotal Trial (Field Administration of Stroke Therapy - Magnesium).

Author

Shkirkova, Kristina, Starkman, Sidney, Sanossian, Nerses, Eckstein, Marc, Stratton, Samuel, Pratt, Frank, Conwit, Robin, Hamilton, Scott, Sharma, Latisha, Liebeskind, David, Restrepo, Lucas, Valdes-Sueiras, Miguel, Saver, Jeffrey L., and FAST-MAG Investigators and Coordinators

Published
2017
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5. Field Validation of the Los Angeles Motor Scale as a Tool for Paramedic Assessment of Stroke Severity.

Author

Joon-Tae Kim, Pil-Wook Chung, Starkman, Sidney, Sanossian, Nerses, Stratton, Samuel J., Eckstein, Marc, Pratt, Frank D., Conwit, Robin, Liebeskind, David S., Sharma, Latisha, Restrepo, Lucas, Tenser, May-Kim, Valdes-Sueiras, Miguel, Gornbein, Jeffrey, Hamilton, Scott, Saver, Jeffrey L., Kim, Joon-Tae, Chung, Pil-Wook, and FAST-MAG Trial (Field Administration of Stroke Therapy–Magnesium) Nurse-Coordinators and Investigators

Published
2017
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7. Enrollment Yield and Reasons for Screen Failure in a Large Prehospital Stroke Trial.

Author

Dae-Hyun Kim, Saver, Jeffrey L., Starkman, Sidney, Liebeskind, David S., Ali, Latisha K., Restrepo, Lucas, Kim-Tenser, May, Valdes-Sueiras, Miguel, Eckstein, Marc, Pratt, Frank, Stratton, Samuel, Hamilton, Scott, Conwit, Robin, Sanossian, Nerses, Kim, Dae-Hyun, and Field Administration of Stroke Therapy–Magnesium (FAST-MAG) Trial Nurse-Coordinators and Investigators

Published
2016
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10. RISK FACTORS.

Author

Stern, Barney, Pullicino, Patrick, and Restrepo, Lucas

Published
2003

19. Abstract T MP52.

Author

Sanoff, Randy, Cherin, Samantha B, Sanossian, Nerses, Conwit, Robin, Hamilton, Scott, Eckstein, Marc, Stratton, Samuel, Pratt, Franklin, Liebeskind, David, Ali, Latisha, Kim- Tenser, May, Restrepo, Lucas, Valdes- Sueiras, Miguel, Starkman, Sidney, and Saver, Jeffrey L

Published
2014

20. Abstract W MP59.

Author

Cherin, Samantha B, Sanossian, Nerses, Ali, Latisha, Restrepo, Lucas, Valdes- Sueiras, Miguel, Hamilton, Scott, Conwit, Robin, Eckstein, Marc, Pratt, Franklin, Stratton, Samuel, Starkman, Sidney, and Saver, Jeffrey L

Published
2014

21. Abstract 129.

Author

Sanossian, Nerses, Starkman, Sidney, Ali, Latisha K, Restrepo, Lucas, Valdes-Sueiras, Miguel, Liebeskind, David S, Chatfield, Fiona, Hodgson, T. Keta, Cherin, Samantha, and Saver, Jeffrey L

Published
2013

22. Abstract WMP66.

Author

Sanoff, Randy, Cherin, Samantha B, Krause, Joan, Chatfield, Fiona, Sanossian, Nerses, Starkman, Sidney, Saver, Jeffrey, Liebeskind, David, Restrepo, Lucas, Ali, Latisha, Valdes-Suerias, Miguel, Kim, May, Obviagele, Bruce, Kim, Doojin, Conwit, Robin, Eckstein, Mark, Pratt, Frank, Hamilton, Scott, and Stratton, Sam

Published
2013

23. Abstract TP203.

Author

Sadighi, Arezou, Cherin, Samantha, Klutch, Rochelle, Craig, Sharon, Chatfield, Fiona, Liebeskind, David, Kim, May, Ali, Latisha, Valdes-Suerias, Miguel, Conwit, Robin, Hamilton, Scott, Eckstein, Marc, Pratt, Frank, Stratton, Samuel, Sanossian, Nerses, Restrepo, Lucas, Starkman, Sidney, and Saver, Jeffrey

Published
2013

24. Abstract TP383.

Author

Cherin, Samantha B, Sanoff, Randy, Chatfield, Fiona, Sanossian, Nerses, Hamilton, Scott, Eckstein, Marc, Pratt, Frank, Stratton, Sam, Liebeskind, David, Kim, Doojin, Restrepo, Lucas, Ali, Latisha, Valdes-Suerias, Miguel, Kim, May, Obviagele, Bruce, Conwit, Robin, Starkman, Sidney, and Saver, Jeffrey

Published
2013

25. Abstract 101.

Author

Modir, Royya F, Rao, Neal, Starkman, Sidney, Sanossian, Nerses, David, Liebeskind, Ali, Latisha, Restrepo, Lucas, Valdes-Sueiras, Miguel, Kim, May, Stratton, Sam, Eckstein, Marc, Pratt, Frank, Conwit, Robin, Hamilton, Scott, and Saver, Jeffrey

Published
2013

26. Abstract 3397.

Author

Yallapragada, Anil, Sanossian, Nerses, Starkman, Sidney, Liebeskind, David, Ali, Latisha, Restrepo, Lucas, Kim-Tenser, May A, Valdes-Sueiras, Miguel, Hamilton, Scott, Eckstein, Marc, Pratt, Franklin D, Stratton, Samuel, Conwit, Robin, and Saver, Jeffrey L

Published
2012

27. Abstract 3309.

Author

Sanossian, Nerses, Starkman, Sidney, Liebeskind, David S, Kim-Tenser, May A, Restrepo, Lucas, Ali, Latisha K, Valdes-Sueiras, Miguel, Conwit, Robin, Hamilton, Scott, and Saver, Jeffrey L

Published
2012

29. Field Validation of the Los Angeles Motor Scale as a Tool for Paramedic Assessment of Stroke Severity.

Author

Kim JT, Chung PW, Starkman S, Sanossian N, Stratton SJ, Eckstein M, Pratt FD, Conwit R, Liebeskind DS, Sharma L, Restrepo L, Tenser MK, Valdes-Sueiras M, Gornbein J, Hamilton S, and Saver JL

Subjects
Aged, Aged, 80 and over, California epidemiology, Emergency Medical Services methods, Emergency Medical Technicians standards, Female, Humans, Male, Middle Aged, Prospective Studies, Reproducibility of Results, Allied Health Personnel standards, Emergency Medical Services standards, Severity of Illness Index, Stroke diagnosis, Stroke epidemiology
Abstract

Background and Purpose: The Los Angeles Motor Scale (LAMS) is a 3-item, 0- to 10-point motor stroke-deficit scale developed for prehospital use. We assessed the convergent, divergent, and predictive validity of the LAMS when performed by paramedics in the field at multiple sites in a large and diverse geographic region., Methods: We analyzed early assessment and outcome data prospectively gathered in the FAST-MAG trial (Field Administration of Stroke Therapy-Magnesium phase 3) among patients with acute cerebrovascular disease (cerebral ischemia and intracranial hemorrhage) within 2 hours of onset, transported by 315 ambulances to 60 receiving hospitals., Results: Among 1632 acute cerebrovascular disease patients (age 70±13 years, male 57.5%), time from onset to prehospital LAMS was median 30 minutes (interquartile range 20-50), onset to early postarrival (EPA) LAMS was 145 minutes (interquartile range 119-180), and onset to EPA National Institutes of Health Stroke Scale was 150 minutes (interquartile range 120-180). Between the prehospital and EPA assessments, LAMS scores were stable in 40.5%, improved in 37.6%, and worsened in 21.9%. In tests of convergent validity, against the EPA National Institutes of Health Stroke Scale, correlations were r=0.49 for the prehospital LAMS and r=0.89 for the EPA LAMS. Prehospital LAMS scores did diverge from the prehospital Glasgow Coma Scale, r=-0.22. Predictive accuracy (adjusted C statistics) for nondisabled 3-month outcome was as follows: prehospital LAMS, 0.76 (95% confidence interval 0.74-0.78); EPA LAMS, 0.85 (95% confidence interval 0.83-0.87); and EPA National Institutes of Health Stroke Scale, 0.87 (95% confidence interval 0.85-0.88)., Conclusions: In this multicenter, prospective, prehospital study, the LAMS showed good to excellent convergent, divergent, and predictive validity, further establishing it as a validated instrument to characterize stroke severity in the field., (© 2017 American Heart Association, Inc.)

Published
2017
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30. Enrollment Yield and Reasons for Screen Failure in a Large Prehospital Stroke Trial.

Author

Kim DH, Saver JL, Starkman S, Liebeskind DS, Ali LK, Restrepo L, Kim-Tenser M, Valdes-Sueiras M, Eckstein M, Pratt F, Stratton S, Hamilton S, Conwit R, and Sanossian N

Subjects
Adult, Emergency Medical Services standards, Female, Humans, Male, Mass Screening standards, Middle Aged, Stroke epidemiology, Treatment Outcome, Emergency Medical Services methods, Mass Screening methods, Patient Selection, Stroke diagnosis
Abstract

Background and Purpose: The enrollment yield and reasons for screen failure in prehospital stroke trials have not been well delineated., Methods: The Field Administration of Stroke Therapy-Magnesium (FAST-MAG) trial identified patients for enrollment using a 2 stage screening process-paramedics in person followed by physician-investigators by cell phone. Outcomes of consecutive screening calls from paramedics to enrolling physician-investigators were prospectively recorded., Results: From 2005 to 2012, 4458 phone calls were made by paramedics to physician-investigators, an average of 1 call per vehicle every 135.7 days. A total of 1700 (38.1%) calls resulted in enrollments. The rate of enrollment of stroke mimics was 3.9%. Among the 2758 patients not enrolled, 3140 reasons for screen failure were documented. The most common reasons for nonenrollment were >2 hours from last known well (17.2%), having a prestroke condition causing disability (16.1%), and absence of a consent provider (9.5%). Novel barriers for phone informed consent specific to the prehospital setting were infrequent, but included: cell phone connection difficulties (3.2%), patient being hard of hearing (1.4%), insufficient time to complete consent (1.3%), or severely dysarthric (1.3%)., Conclusions: In this large, multicenter prehospital trial, nearly 40% of every calls from the field to physician-investigators resulted in trial enrollments. The most common reasons for nonenrollment were out of window last known well time, prestroke confounding medical condition, and absence of a consent provider., Clinical Trial Registration: URL: http://www.clinicaltrials.gov. Unique identifier: NCT00059332., (© 2015 American Heart Association, Inc.)

Published
2016
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31. Central nervous system compromise in primary Sjögren's syndrome.

Author

Anaya JM, Villa LA, Restrepo L, Molina JF, Mantilla RD, and Vargas S

Abstract

Central nervous system (CNS) involvement in primary Sjögren's syndrome (SS) is poorly understood, and its frequency as well as its manifestations are subjects of controversy. The current study was undertaken to determine the prevalence and the clinical and immunogenetic characteristics of CNS compromise in a well defined group of patients with primary SS. In this retrospective study, patients fulfilled the European classification criteria. Among 120 patients with primary SS, 3 (2.5%) had CNS compromise (multiple sclerosis-like illness, complicated migraine, and optic neuritis with epilepsy). The CNS involvement coincided with the onset of sicca symptoms in 1 case. All 3 patients carried the human leukocyte antigen (HLA) DQB1*0303 allele and tested positive for anti-Ro antibodies, but not for anti-cardiolipin antibodies. Although rare, CNS compromise in primary SS can be the presenting manifestation of the disease in a few cases, and may be severe and varied.

Published
2002
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