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The article offers information on endogenous bacterial and fungal endogenous endophthalmitis (EE). EE is caused by the spread of bacterial or fungal organisms to eye. Predisposing factors that make patients susceptible to EE include intravenous hyperalimentation, intravenous or indwelling catheter and antibiotic therapy. Diagnostic aspect in cases of EE, medical treatment and surgical treatment of EE are discussed.

The article focuses on the development of serious retinal detachments secondary to lupus choroidopathy in patients with lupus erythematosus. Choroidopathy may be a manifestation of central serous chorioretinopathy from systemic corticosteroids used to treat the lupus. The treatment of choice in the condition is the withdrawal or decreasing of the steroids.

Background: Acute humoral rejection (AHR) has been associated with enhanced graft loss. Our study compared the renal allograft survival of patients with AHR treated with plasmapheresis (PP) and intravenous immunoglobulin (IVIG) with allograft survival in patients with acute cellular rejection (ACR)., Methods: We retrospectively analyzed all kidney transplants performed at our institution between January 1999 and August 2001 (n=286). Recipients were classified into three groups according to biopsy reports: AHR, ACR, or no rejection. The ACR group was further divided into early and late rejection (<90 and >90 days posttransplant, respectively)., Results: After a mean follow-up of 569+/-19 days, the incidence of AHR was 5.6% (n=16). Recipient presensitization, delayed graft function, early rejection, and higher creatinine at diagnosis were characteristic of AHR. Most AHR patients (14/16) were treated with PP and IVIG. One patient received only IVIG, whereas another received only PP. All AHR patients were given steroid pulses, but only four received antilymphocyte therapy because of concomitant severe ACR. The ACR group comprised 43 patients (15%). One patient with mild rejection received no therapy, 20 improved with steroids alone, and 22 required additional antilymphocyte therapy. One-year graft survival by Kaplan Meier analysis was 81% and 84% in the AHR and ACR groups, respectively (P=NS). Outcomes remained similar when AHR patients were compared with those with early ACR., Conclusions: We conclude that AHR, when diagnosed early and treated aggressively with PP and IVIG, carries a short-term prognosis that is similar to ACR.