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Your search keyword '"Tickoo, Satish K"' showing total 25 results
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25 results on '"Tickoo, Satish K"'

3. TFEB Expression Profiling in Renal Cell Carcinomas: Clinicopathologic Correlations.

Author

Gupta, Sounak, Argani, Pedram, Jungbluth, Achim A., Chen, Ying-Bei, Tickoo, Satish K., Fine, Samson W., Gopalan, Anuradha, Al-Ahmadie, Hikmat A., Sirintrapun, Sahussapont J., Sanchez, Alejandro, Hakimi, Abraham Ari, Mcfarlane, Tiffany, Salazar, Paulo A., Williamson, Sean R., Skala, Stephanie L., Mehra, Rohit, Hes, Ondrej, Antonescu, Cristina R., Ladanyi, Marc, and Arcila, Maria E.

Published
2019
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5. PD-L1 Expression in Urothelial Carcinoma With Predominant or Pure Variant Histology: Concordance Among 3 Commonly Used and Commercially Available Antibodies.

Author

Reis, Henning, Serrette, Rene, Posada, Jennifer, Lu, Vincent, Chen, Ying-bei, Gopalan, Anuradha, Fine, Samson W., Tickoo, Satish K., Sirintrapun, Sahussapont J., Iyer, Gopa, Funt, Samuel A., Teo, Min Yuen, Rosenberg, Jonathan E., Bajorin, Dean F., Dalbagni, Guido, Bochner, Bernard H., Solit, David B., Reuter, Victor E., and Al-Ahmadie, Hikmat A.

Published
2019
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9. Challenges in Pathologic Staging of Renal Cell Carcinoma: A Study of Interobserver Variability Among Urologic Pathologists.

Author

Williamson, Sean R., Rao, Priya, Hes, Ondrej, Epstein, Jonathan I., Smith, Steven C., Picken, Maria M., Zhou, Ming, Tretiakova, Maria S., Tickoo, Satish K., Chen, Ying-Bei, Reuter, Victor E., Fleming, Stewart, Maclean, Fiona M., Gupta, Nilesh S., Kuroda, Naoto, Delahunt, Brett, Mehra, Rohit, Przybycin, Christopher G., Cheng, Liang, and Eble, John N.

Published
2018
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23. Sarcomatoid-variant renal cell carcinoma: treatment outcome and survival in advanced disease.

Author

Molina AM, Tickoo SK, Ishill N, Trinos MJ, Schwartz LH, Patil S, Feldman DR, Reuter VE, Russo P, and Motzer RJ

Subjects
Adult, Aged, Aged, 80 and over, Bone Neoplasms drug therapy, Bone Neoplasms mortality, Bone Neoplasms secondary, Carcinoma, Papillary drug therapy, Carcinoma, Papillary secondary, Carcinoma, Renal Cell drug therapy, Carcinoma, Renal Cell secondary, Cohort Studies, Female, Follow-Up Studies, Humans, Kidney Neoplasms drug therapy, Kidney Neoplasms pathology, Liver Neoplasms drug therapy, Liver Neoplasms mortality, Liver Neoplasms secondary, Lung Neoplasms drug therapy, Lung Neoplasms mortality, Lung Neoplasms secondary, Lymphatic Metastasis, Male, Middle Aged, Retrospective Studies, Survival Rate, Treatment Outcome, Antineoplastic Combined Chemotherapy Protocols therapeutic use, Carcinoma, Papillary mortality, Carcinoma, Renal Cell mortality, Kidney Neoplasms mortality
Abstract

Objectives: Sarcomatoid variant is a spindle cell phenotype of renal cell carcinoma (RCC), which is associated with a poor prognosis. We reviewed outcomes of systemic therapy for metastatic, sarcomatoid-variant RCC., Methods: Clinical features, treatment outcome, and survival were evaluated in 63 patients with sarcomatoid-variant metastatic RCC (47 clear cell, 16 nonclear cell). Initial systemic treatment included antiangiogenesis-targeted therapy (n=34), cytokines (n=20), and chemotherapy (n=9)., Results: Five of 63 patients (8%) achieved an objective response to the first systemic treatment: 1 (5%) to cytokine and 4 (12%) to sunitinib-targeted therapy. Median progression-free survival for 63 patients was 3 months (95% confidence interval), and median overall survival was 10 months (95% confidence interval). The median progression-free survival for patients treated with sunitinib versus all others was 4.4 months versus 2 months (P=0.03), and 3 months for patients with clear-cell histology versus 1.6 months for nonclear-cell histology (P=0.004)., Conclusions: Metastatic sarcomatoid-variant RCC was associated with a poor response to systemic therapy. Sunitinib treatment resulted in a modest response rate, but studies to characterize the underlying tumor biology of sarcomatoid-variant RCC, to assess outcome to targeted agents, and to develop novel treatment strategies are warranted.

Published
2011
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24. Differential diagnosis of renal tumours with clear cell histology.

Author

Reuter VE and Tickoo SK

Subjects
Biomarkers, Tumor metabolism, Carcinoma, Renal Cell metabolism, Diagnosis, Differential, Humans, Immunohistochemistry, Kidney Neoplasms classification, Kidney Neoplasms metabolism, Carcinoma, Renal Cell classification, Carcinoma, Renal Cell pathology, Kidney Neoplasms pathology
Abstract

Clear cell renal cell carcinoma is the most common malignant renal epithelial tumour and constitutes 90% of cases that metastasise. Nevertheless, it is important to recognise that not all clear cell carcinomas contain a preponderance of clear cells and that other renal tumours with different biologies and sensitivities to systemic therapeutic agents may exhibit clear cell cytology. Close attention to the cytological and growth pattern characteristics will allow us to arrive at the proper diagnosis, sometimes with the aid of immunohistochemistry.

Published
2010
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25. Anatomy of the anterior prostate and extraprostatic space: a contemporary surgical pathology analysis.

Author

Fine SW, Al-Ahmadie HA, Gopalan A, Tickoo SK, Scardino PT, and Reuter VE

Subjects
Dissection, Humans, Male, Pathology, Surgical methods, Prostate surgery, Prostatectomy, Seminal Vesicles anatomy & histology, Prostate anatomy & histology
Abstract

Over 25 years ago, McNeal described a model of prostatic zonal anatomy based on autopsy dissections in various planes. As opposed to the cone-shaped organ seen in vivo, radical prostatectomy specimens are typically spherical, owing to tissue contraction at surgical removal and subsequent processing. Sectioning from apex to base yields topography at the Surgical Pathology "sign-out" that may vary from McNeal's descriptions. There are no in depth studies of anterior prostatic anatomic variability, including the periurethral region, peripheral (PZ) and transition (TZ) zones, anterior fibromuscular stroma (AFMS), and anterior extraprostatic space (EPS) using modern prosecting techniques. Detailed analysis of 197 entirely submitted, whole-mounted radical prostatectomy specimens focused on differences in zonal anatomy from apex through base, the relationship of AFMS to PZ and TZ, and the nature of the anterior EPS revealed features that may have significant impact on determination of zonal origin and pathologic staging of anteriorly situated prostate cancer. Among these observations are the predominant nature of the anterior PZ at the apex and the potential for its broad contact with the AFMS at this location, the differing volumes and location of the TZ in prostates with and without benign prostatic hyperplasia, and the composition of the anterior EPS, including adipose tissue, blood vessels, and skeletal muscle at the apex varying to include medium to large smooth muscle bundles at the base.

Published
2007
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