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Your search keyword '"van Velzen, Monique"' showing total 25 results
Start Over Author "van Velzen, Monique" Publisher lippincott williams & wilkins
25 results on '"van Velzen, Monique"'

2. Naloxone for Opioid Overdose: Reply.

Author

van Lemmen, Maarten, Florian, Jeffrey, Zhihua Li, van Velzen, Monique, van Dorp, Eveline, Niesters, Marieke, Sarton, Elise, Olofsen, Erik, van der Schrier, Rutger, Strauss, David G., and Dahan, Albert

Published
2024
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5. Ketamine Psychedelic and Antinociceptive Effects Are Connected.

Author

Olofsen, Erik Ph.D., Kamp, Jasper Ph.D., Henthorn, Thomas K. M.D., van Velzen, Monique Ph.D., Niesters, Marieke M.D., Ph.D., Sarton, Elise M.D., Ph.D., Dahan, Albert M.D., Ph.D., Olofsen, Erik, Kamp, Jasper, Henthorn, Thomas K, van Velzen, Monique, Niesters, Marieke, Sarton, Elise, and Dahan, Albert

Published
2022
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6. Advances in Reversal Strategies of Opioid-induced Respiratory Toxicity.

Author

van der Schrier, Rutger M.D., Dahan, Jack D. C. B.Sc., Boon, Martijn M.D., Ph.D., Sarton, Elise M.D., Ph.D., van Velzen, Monique Ph.D., Niesters, Marieke M.D., Ph.D., Dahan, Albert M.D., Ph.D., van der Schrier, Rutger, Dahan, Jack D C, Boon, Martijn, Sarton, Elise, van Velzen, Monique, Niesters, Marieke, and Dahan, Albert

Published
2022
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10. Efficacy of ketamine in relieving neuropathic pain: a systematic review and meta-analysis of animal studies.

Author

van Velzen, Monique, Dahan, Jack D. C., van Dorp, Eveline L. A., Mogil, Jeffrey S., Hooijmans, Carlijn R., Dahan, Albert, and Velzen, Monique van

Subjects
*RESEARCH, *META-analysis, *NEURALGIA, *ANIMAL experimentation, *RESEARCH methodology, *SYSTEMATIC reviews, *MEDICAL cooperation, *EVALUATION research, *RATS, *COMPARATIVE studies, *KETAMINE, *HYPERALGESIA, *MICE
Abstract

Abstract: In humans, proof of long-term efficacy of ketamine treatment in neuropathic pain is lacking. To improve our understanding of ketamine behavior under various administration conditions, we performed a systematic review and meta-analyses of controlled studies on the efficacy of ketamine in mice and rats with a disease model of nerve injury on relief of allodynia. Searches in PubMed and EMBASE identified 31 unique studies. Four meta-analyses were conducted. The first analysis included 19 comparisons on a single ketamine dose and measurement of effect within 3 hours of dosing and showed an appreciable effect (standardized mean difference 1.6, 95% confidence interval 1.1-2.1). Subgroup analyses showed no effect of species, administration route, or dose. A single administration was insufficient to sustain relief of allodynia at 24 or 72 hours after dosing, as observed in our second analysis (7 comparisons) with similar effects in ketamine-treated and control animals. Chronic ketamine administration (9 comparisons) caused profound relief of allodynia when tested during ketamine exposure (effect size 5.1, 3.7-6.5). The final analysis (6 comparisons) showed that chronic administration caused a slow loss of relief of allodynia with 70% loss of effect 24 days after end of treatment. No subgroups analyses were possible in the last 3 meta-analyses due to small group sizes. These results indicate long-term ketamine anti-allodynic effects after chronic exposure (>3 days) but not after a single administration. Given several limitations, extrapolation of the animal data to the human condition is tenuous. [ABSTRACT FROM AUTHOR]

Published
2021
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11. Ketamine Pharmacokinetics.

Author

Kamp, Jasper, Olofsen, Erik, Henthorn, Thomas K., van Velzen, Monique, Niesters, Marieke, Dahan, Albert, Backman, Janne T., Drover, David R., Elkomy, Mohammed H., Fanta, Samuel, Flint, Robert B., Gustafsson, Lars L., Hammer, Gregory B., Herd, David W., Kalso, Eija, Mathôt, Ron A.A., Olkkola, Klaus, Peltoniemi, Marko, Persson, Jan, and Ramamoorthy, Chandra

Published
2020
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22. Translation of random painful stimuli into numerical responses in fibromyalgia and perioperative patients.

Author

Oudejans, Linda, van Velzen, Monique, Olofsen, Erik, Beun, Robert, Dahan, Albert, and Niesters, Marieke

Subjects
*AVERSIVE stimuli, *FIBROMYALGIA, *PERIOPERATIVE care, *CHRONIC pain, *DRUG therapy, *OPIOIDS, *DATA analysis, *CONTROL groups, *ELECTRIC stimulation, *POSTOPERATIVE pain, *PAIN measurement, *PAIN threshold, *DIAGNOSIS
Abstract

Number-based assessment tools are used to evaluate pain perception in patients and determine the effect of pain management. The aim of this study was to determine the ability of chronic and acute pain patients to score their response to randomly applied noxious stimuli and assess the effect of opioid treatment. Thirty-seven healthy controls, 30 fibromyalgia patients, and 62 postoperative patients with acute pain received random heat pain (Hp) and electrical pain (Ep) stimuli. All subjects rated their pain on an 11-point numerical rating scale (NRS). The data were analyzed using a penalty score system, based on the assumption that stimuli of higher intensity are scored with a greater NRS, and stratified into cohorts corresponding to "good," "mediocre," and "poor" scoring. Healthy controls were well able to score pain with 73% (Hp) and 81% (Ep) of subjects classified into cohort "good." Fibromyalgia had a negative effect on scoring with 45% (Hp, P = 0.03 vs controls) and 67% (Ep) of patients in cohort "good." In controls, scoring deteriorated during opioid administration leaving just 40% (Hp, P = 0.015 vs baseline) and 70% (Ep) of subjects in the cohort "good." Similar observations were made in fibromyalgia patients (P = 0.02) but not in surgical patients with postoperative pain. Consistency to grade pain using an NRS is high in healthy volunteers but deteriorates in chronic pain and during opioid administration to volunteers and chronic pain patients but not to acute pain patients. [ABSTRACT FROM AUTHOR]

Published
2016
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