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Your search keyword '"Patrinos, George P."' showing total 29 results
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29 results on '"Patrinos, George P."'

3. How Can We Boost the Pharmacogenomics Adoption Rate in Clinical Practice Around the World?

Author

Vasileiou, Konstantinos Z. and Patrinos, George P.

Subjects
*PHARMACOGENOMICS, *MEDICAL personnel, *MEDICAL care, *DRUG side effects
Abstract

This letter discusses the current state of pharmacogenomics (PGx) adoption in clinical practice worldwide. The authors note that while there is increasing interest in PGx applications from various stakeholders, such as academic/research communities and health care professionals, there are still barriers to wider adoption. These barriers include a lack of knowledge and confidence among health care professionals, as well as a lack of clear clinical guidance and protocols. However, there are positive attitudes and intentions among health care professionals regarding PGx implementation, as it has the potential to optimize drug response and improve patient satisfaction. The authors declare no conflicting financial interests, and no funding was received for this letter. [Extracted from the article]

Published
2024
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5. Horizon Scanning: Teaching Genomics and Personalized Medicine in the Digital Age.

Author

Patrinos, George P. and Mitropoulou, Christina

Subjects
*INDIVIDUALIZED medicine, *MEDICAL personnel, *GENOMICS, *DIGITAL health, *HEALTH literacy, *PHARMACOGENOMICS
Abstract

Digital transformation is currently impacting not only health care but also education curricula for medicine and life sciences. The COVID-19 pandemic has accelerated the deployment of digital technologies such as the Internet of Things and artificial intelligence in diverse fields of biomedicine. Genomics and related fields of inquiry such as pharmacogenomics and personalized medicine have been making important progress over the past decades. However, the genomics knowledge of health care professionals and other stakeholders in society is not commensurate with the current state of progress in these scientific fields. The rise of digital health offers unprecedented opportunities both for health care professionals and the general public to expand their genomics literacy and education. This expert review offers an analysis of the bottlenecks that affect and issues that need to be addressed to catalyze genomics and personalized medicine education in the digital era. In addition, we summarize and critically discuss the various educational and awareness opportunities that presently exist to catalyze the delivery of genomics knowledge in ways closely attuned to the emerging field of digital health. [ABSTRACT FROM AUTHOR]

Published
2022
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20. David Bowie and the Art of Slow Innovation: A Fast-Second Winner Strategy for Biotechnology and Precision Medicine Global Development.

Author

Özdemir, Vural and Patrinos, George P.

Subjects
*INDIVIDUALIZED medicine, *BIOTECHNOLOGY, *DIAGNOSTIC imaging, *TECHNOLOGICAL innovations
Abstract

Original ideas and innovation cannot always be ordered like a courier service and delivered fresh to our desk at 9 am. Yet, most creativity-based organizations, careers, and professions, science and biotechnology innovation included, emphasize the speed as the prevailing ideology. But a narrow focus on speed has several and overlooked shortcomings. For example, it does not offer the opportunity to draw from, and stitch together disparate concepts and practices for truly disruptive innovation. Preventing false starts, learning from others' or our own mistakes, and customizing innovations for local community needs are difficult in a speed-hungry innovation ecosystem. We introduce a new strategy, the Fast-Second Winner, specifically in relation to global development of biotechnologies and precision medicine. This à la carte global development strategy envisions a midstream entry into the innovation ecosystem. Moreover, we draw from the works of the late David Bowie who defied rigid classifications as an artist and prolific innovator, and introduce the concept and practice of slow innovation that bodes well with the Fast-Second Winner strategy. A type of slow innovation, the Fast-Second Winner is actually fast and sustainable in the long term, and efficient by reducing false starts in new precision medicine application contexts and geographies, learning from other innovators' failures, and shaping innovations for the local community needs. The establishment of Centers for Fast-Second Innovation (CFSIs), and their funding, for example, by crowdfunding and other innovative mechanisms, could be timely for omics and precision medicine global development. If precision medicine is about tailoring drug treatments and various health interventions to individuals, we suggest to start from tailoring new ideas, and focus not only on how much we innovate but also what and how we innovate. In principle, the Fast-Second Winner can be applied to omics and other biotechnology responsible development in medical practice or any field of applied innovation. [ABSTRACT FROM AUTHOR]

Published
2017
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