1. Continuous Glucose Monitoring in 2015
- Author
-
Takeshi Inoue, Hiroto Kinutani, Hirotoshi Hariki, Kazuhiko Sakaguchi, Yu Taniguchi, Masamichi Iwasaki, Masaru Kuroda, Akihide Konishi, Masayuki Nakagawa, Toshiro Shinke, Daisuke Terashita, Ken-ichi Hirata, Hachidai Takahashi, Hiromasa Otake, Ryo Nishio, Tomofumi Takaya, Yushi Hirota, Daisuke Sugiyama, Noritoshi Hiranuma, and Tsuyoshi Osue
- Subjects
Adult ,Blood Glucose ,medicine.medical_specialty ,Endocrinology, Diabetes and Metabolism ,medicine.medical_treatment ,Diabetes Complications ,Coronary artery disease ,Endocrinology ,Internal medicine ,Diabetes mellitus ,medicine ,Humans ,In patient ,Child ,Prospective cohort study ,business.industry ,Blood Glucose Self-Monitoring ,Percutaneous coronary intervention ,Middle Aged ,medicine.disease ,Surgery ,Residual risk ,Medical Laboratory Technology ,Diabetes Mellitus, Type 1 ,Diabetes Mellitus, Type 2 ,Hyperglycemia ,Cardiology ,Observational study ,business ,Dyslipidemia - Abstract
Objectives This study sought to investigate the effect of daily glucose fluctuation on coronary plaque properties in patients with coronary artery disease (CAD) pre-treated with lipid-lowering therapy. Background There is growing evidence that glucose fluctuation, as a residual risk apart from dyslipidemia, is an important factor contributing to the development of CAD. Methods This prospective study enrolled 70 consecutive CAD patients who were referred for percutaneous coronary intervention and whose low-density lipoprotein cholesterol level was Results In total, 165 lesions were evaluated in 70 patients (40 diabetic and 30 nondiabetic patients). %NC was well correlated with MAGE (r = 0.490, p Conclusions Daily glucose fluctuation may have an effect on coronary plaque vulnerability in patients with CAD pre-treated with lipid-lowering therapy. Further investigations should address the rationale for the early detection and control of glucose fluctuation in the era of universal statin use for CAD patients.
- Published
- 2016