1. A Lipid-Soluble Red Ginseng Extract Inhibits the Growth of Human Lung Tumor Xenografts in Nude Mice
- Author
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Junsoo Lee, Song-Kyu Park, Kwang Seung Lee, Eun Sil Lee, Chang Woo Lee, Dong Chung Kim, Sung Dong Lee, Hwan Mook Kim, Ki Hoon Lee, Kiho Lee, Woo Ik Hwang, and Moo Rim Kang
- Subjects
Lung Neoplasms ,Mice, Nude ,Panax ,Medicine (miscellaneous) ,Pharmacology ,complex mixtures ,Mice ,Ginseng ,GINSENG EXTRACT ,Oral administration ,Cell Line, Tumor ,Animals ,Humans ,Medicine ,Cytotoxicity ,Lung cancer ,Cell Proliferation ,Mice, Inbred BALB C ,Nutrition and Dietetics ,Dose-Response Relationship, Drug ,Plant Extracts ,business.industry ,food and beverages ,medicine.disease ,Antineoplastic Agents, Phytogenic ,Lipids ,Xenograft Model Antitumor Assays ,In vitro ,Disease Models, Animal ,Solubility ,Cell culture ,Toxicity ,Female ,business ,Phytotherapy - Abstract
Lipid-soluble ginseng extract was prepared by n-hexane extraction of red ginseng. BALB/c-nu mice were inoculated with human lung cancer (NCI-H460) cells to establish a human tumor xenograft model in nude mice, and the lipid-soluble ginseng extract was orally administered. The tumor inhibitory rates of the lipid-soluble ginseng extract at doses of 0.1, 0.3, and 1.0 g/kg/day were 18.9% (P
- Published
- 2010
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