Search

Simple Summary: Vegetation communities are impacted by invasive plants in predictable ways, namely, reductions in species richness, diversity, and floristic quality (i.e., the "nativeness" of the plant community). In ecological restoration, these plant community properties are important in establishing performance standards, especially for restored wetlands and streams. Performance standards can be thought of as the "report card" for ecological restoration. In the United States, much of this ecosystem restoration occurs as compensatory mitigation (i.e., to compensate for impacts to wetlands and streams elsewhere). The presence of invasive plant species is an important performance standard used in compensatory mitigation to determine whether or not wetland and stream mitigation sites comply with environmental laws. Invasive plants detract from restoration performance, but it is unclear what level of invasion should trigger a legal requirement for invasive plant removal. This study found that lower levels of invasion (i.e., 5–10%) do not diminish native vegetation community properties on wetland and stream mitigation sites, so low invasive performance standards could be causing more harm than good via the loss of native species from treatments like broad-spectrum chemical herbicides. Our research points to a more moderate standard of 10%, along with annual invasive mapping. We sampled vegetation communities across plant invasion gradients at multiple wetland and stream mitigation sites in the Coastal Plain and Piedmont physiographic provinces of Virginia, USA. Impacts of invasion were evaluated by tracking changes in species composition and native vegetation community properties along the abundance gradients of multiple plant invaders. We found that native species richness, diversity, and floristic quality were consistently highest at moderate levels of invasion (ca. 5–10% relative abundance of invader), regardless of the identity of the invasive species or the type of mitigation (wetland or stream). Likewise, native species composition was similar between uninvaded and moderately invaded areas, and only diminished when invaders were present at higher abundance values. Currently, low thresholds for invasive species performance standards (e.g., below 5% relative abundance of invader) compel mitigation managers to use non-selective control methods such as herbicides to reduce invasive plant cover. Our results suggest that this could cause indiscriminate mortality of desirable native species at much higher levels of richness, diversity, and floristic quality than previously thought. From our data, we recommend an invasive species performance standard of 10% relative invader(s) abundance on wetland and stream mitigation sites, in combination with vigilant invasive plant mapping strategies. Based on our results, this slightly higher standard would strike a balance between proactive management and unnecessary loss of plant community functions at the hands of compulsory invasive species management. [ABSTRACT FROM AUTHOR]

To meet European carbon neutrality targets and comply with building energy performance regulations, renovating historic buildings is considered one of the most challenging tasks for the construction sector. On one hand, commonly employed renovation solutions are often more difficult to implement on these structures. On the other hand, renovation work must be carried out while preserving their heritage value and integrity. The European standard EN 16883 on conservation and energy renovation performance of cultural heritage was developed in 2017 with the aim of facilitating energy performance improvements in historic buildings while respecting their cultural significance. In pursuit of the same objective, the "P-Renewal" project focuses on the energy retrofit of pre-war Walloon housing with heritage value, providing valuable support through a reflective process and decision-making tools. These tools enable the selection of renovation strategies that effectively combine the preservation of heritage value with improvements in internal comfort, energy efficiency, and environmental performance. This study compares the reflective process of the research project with the guidelines of the standard EN 16883 and discusses the transferability of this contribution to other European contexts. This will significantly contribute to the evolution of energy performance standards for the renovation of historic buildings. [ABSTRACT FROM AUTHOR]

The VEMoS-AXL system is a new optical biometer based on spectral domain optical coherence tomography (SD-OCT) that has been tested in terms of intrasession repeatability and compared with a swept-source optical coherence tomography biometer (SS-OCT), which is recognized as the gold standard for the performance of an agreement analysis. A biometric analysis was performed three consecutive times in 120 healthy eyes of 120 patients aged between 18 and 40 years with the SD-OCT system, and afterwards, a single measurement was obtained with the SS-OCT system. Within-subject standard deviations were 0.004 mm, 4.394 µm, and 0.017 mm for axial length (AL), central corneal thickness (CCT), and anterior chamber depth (ACD) measures obtained with the SD-OCT biometer, respectively. The agreement between devices was good for AL (limits of agreement, LoA: −0.04 to 0.03 mm) and CCT (LoA: −4.36 to 14.38 µm), whereas differences between devices were clinically relevant for ACD (LoA: 0.03 to 0.21 mm). In conclusion, the VEMoS-AXL system provides consistent measures of anatomical parameters, being most of them interchangeable with those provided by the SS-OCT-based gold standard. [ABSTRACT FROM AUTHOR]

Electrowetting with a dielectric layer is commonly preferred in practical applications. However, its potential is often limited by factors like the properties of the dielectric layer and its breakdown, along with the complexity of the deposition method. Fortunately, advancements in 3D inkjet printing offer a more adaptable solution for making patterned functional layers. In this study, we used a negative photoresist (HN-1901) to create a new dielectric layer for an electrowetting display on a 3-inch ITO glass using a Dimatix DMP-2580 inkjet printer. The resulting devices performed better due to their enhanced resistance to dielectric breakdown. We meticulously investigated the physical properties of the photoresist material and printer settings to achieve optimal printing. We also controlled the uniformity of the dielectric layer by adjusting ink drop spacing. Compared to traditional electrowetting display devices, those with inkjet-printed dielectric layers showed significantly fewer defects like bubbles and electrode corrosion. They maintained an outstanding response time and breakdown resistance, operating at an open voltage of 20 V. Remarkably, these devices achieved faster response times of ton 22.3 ms and toff 14.2 ms, surpassing the performance of the standard device. [ABSTRACT FROM AUTHOR]

The engineering of quantum computers requires the reliable characterization of qubits, quantum operations, and even the entire hardware. Quantum tomography is an indispensable framework in quantum characterization, verification, and validation (QCVV), which has been widely accepted by researchers. According to the tomographic target, quantum tomography can be categorized into quantum state tomography (QST), quantum process tomography (QPT), gate set tomography (GST), process tensor tomography (PTT), and instrument set tomography (IST). Standard quantum tomography toolkits generally consist of basic linear inverse methods and statistical maximum likelihood estimation (MLE)-based methods. Furthermore, the performance of standard methods, including effectiveness and efficiency, has been further developed by exploiting Bayesian estimation, neural networks, matrix completion techniques, etc. In this review, we introduce the fundamental quantum tomography techniques, including QST, QPT, GST, PTT, and IST. We first introduce the details of basic linear inverse methods. Then, the framework of MLE methods with constraints is summarized. Finally, we briefly introduce recent further research in developing the performance of tomography, utilizing some symmetry properties of the target. This review provides a primary getting-start in developing quantum tomography, which promotes quantum computer development. [ABSTRACT FROM AUTHOR]

A novel approach for video instance segmentation is presented using semisupervised learning. Our Cluster2Former model leverages scribble-based annotations for training, significantly reducing the need for comprehensive pixel-level masks. We augment a video instance segmenter, for example, the Mask2Former architecture, with similarity-based constraint loss to handle partial annotations efficiently. We demonstrate that despite using lightweight annotations (using only 0.5% of the annotated pixels), Cluster2Former achieves competitive performance on standard benchmarks. The approach offers a cost-effective and computationally efficient solution for video instance segmentation, especially in scenarios with limited annotation resources. [ABSTRACT FROM AUTHOR]

We evaluated the diagnostic performance of the STANDARD i-Q COVID-19 Ag Test, which was developed to detect viral antigens, using nasal and oral swabs. Sixty positive and 100 negative samples were analyzed. We determined the distribution of the Ct values according to the day of sample collection after symptom onset, the diagnostic performance of the total samples and subgroups separated by Ct value or time of sample collection, and the Ct value at which maximal accuracy was expected. No differences were observed in Ct values, except for the samples obtained on the day of symptom onset. The diagnostic sensitivity and specificity of the oral swabs were 75.0 and 100.0%, respectively, whereas those of the nasal swabs were 85.0 and 98.0%, respectively. The sensitivity was higher in samples with a high viral load collected earlier than those collected later, although the difference was not significant. False-negative results were confirmed in all samples with a Ct value ≥ 30.0. These results indicate that tests using oral and nasal swabs are helpful for diagnosing acute symptomatic cases with suspected high viral loads. Our tests exhibited relatively low sensitivity but high specificity rates, indicating the need to assess negative antigen test results. [ABSTRACT FROM AUTHOR]

The intracellular and intercellular flux of calcium ions represents an ancient and universal mode of signaling that regulates an extensive array of cellular processes. Evidence for the central role of calcium signaling includes various techniques that allow the visualization of calcium activity in living cells. While extensively investigated in mature cells, calcium activity is equally important in developing cells, particularly the embryonic nervous system where it has been implicated in a wide variety array of determinative events. However, unlike in mature cells, where the calcium dynamics display regular, predictable patterns, calcium activity in developing systems is far more sporadic, irregular, and diverse. This renders the ability to assess calcium activity in a consistent manner extremely challenging, challenges reflected in the diversity of methods employed to analyze calcium activity in neural development. Here we review the wide array of calcium detection and analysis methods used across studies, limiting the extent to which they can be comparatively analyzed. The goal is to provide investigators not only with an overview of calcium activity analysis techniques currently available, but also to offer suggestions for future work and standardization to enable informative comparative evaluations of this fundamental and important process in neural development. [ABSTRACT FROM AUTHOR]

For many years, chaotic maps have been widely used in the design of various algorithms in cryptographic systems. In this paper, a new model (compound chaotic system) of quantum random walks controlled by a hyper-chaotic map is constructed and a novel scheme for constructing a dynamic S-Box based on the new model is proposed. Through aperiodic evaluation and statistical complexity measurement, it is shown that the compound chaotic system has features such as complex structure and stronger randomness than classical chaotic systems. Based on the chaotic sequence generated by the composite system, we design a dynamic S-Box generation mechanism. The mechanism can quickly generate high-security S-Boxes. Then, an example of randomly generating S-Boxes is given alongside an analytical evaluation of S-Box standard performance criteria such as bijection, boomerang uniformity, bit independence, nonlinearity, linear approximate probability, strict avalanche effect, differential uniformity, the and generalized majority logic criterion. The evaluation results confirm that the performance of the S-Box is excellent. Thus, the proposed dynamic S-Box construction technique can be used to generate cryptographically strong substitution-boxes in practical information security systems. [ABSTRACT FROM AUTHOR]

The effects of six control parameters, intake valve opening timing (IVO), exhaust valve opening timing (EVO), compression ratio (CR), engine speed, intake temperature, and intake pressure on engine output power, indicated specific fuel consumption (ISFC), and nitrogen oxides (NOx) emissions, are analyzed through engine simulation. The six parameters were categorized into two groups based on the degree of influence: high influence (EVO, speed and intake pressure) and low influence (CR, IVO and intake temperature). The relationship between these two groups of parameters and power, ISFC and NOx emissions was explored. Optimization was carried out for each of the two groups of parameters, and the optimization of the high impact parameters resulted in a higher diversity and wider distribution of the solution set. On the other hand, the optimization of the low-impact parameters resulted in a more concentrated distribution of the solution set, while better reflecting the trade-off between the optimization objectives. For the optimal solutions for both sets of parameters, the high-impact parameters provided significant optimization performance compared to the standard operating conditions. Although power and ISFC were optimized, the optimal solution for the low-impact parameter performed poorly with a significant increase in NOx emissions. Therefore, the parameters should be evaluated for optimization using high impact parameters to improve engine performance. [ABSTRACT FROM AUTHOR]

Dynamic multi-objective optimization problems (DMOPs) are optimization problems where elements of the problems, such as the objective functions and/or constraints, change with time. These problems are characterized by two or more objective functions, where at least two objective functions are in conflict with one another. When solving real-world problems, the incorporation of human decision-makers (DMs)' preferences or expert knowledge into the optimization process and thereby restricting the search to a specific region of the Pareto-optimal Front (POF) may result in more preferred or suitable solutions. This study proposes approaches that enable DMs to influence the search process with their preferences by reformulating the optimization problems as constrained problems. The subsequent constrained problems are solved using various constraint handling approaches, such as the penalization of infeasible solutions and the restriction of the search to the feasible region of the search space. The proposed constraint handling approaches are compared by incorporating the approaches into a differential evolution (DE) algorithm and measuring the algorithm's performance using both standard performance measures for dynamic multi-objective optimization (DMOO), as well as newly proposed measures for constrained DMOPs. The new measures indicate how well an algorithm was able to find solutions in the objective space that best reflect the DM's preferences and the Pareto-optimality goal of dynamic multi-objective optimization algorithms (DMOAs). The results indicate that the constraint handling approaches are effective in finding Pareto-optimal solutions that satisfy the preference constraints of a DM. [ABSTRACT FROM AUTHOR]

Given the challenges associated with the dynamic expansion of the conventional bloom filter's capacity, the prevalence of false positives, and the subpar access performance, this study employs the algebraic and topological characteristics of p-adic integers to introduce an innovative approach for dynamically expanding the p-adic Integer Scalable Bloom Filter (PSBF). The proposed method involves converting the target element into an integer using a string hash function, followed by the conversion of said integer into a p-adic integer through algebraic properties. This process automatically establishes the topological tree access structure of the PSBF. The experiment involved a comparison of access performance among the standard bloom filter, dynamic bloom filter, and scalable bloom filter. The findings indicate that the PSBF offers advantages such as avoidance of a linear storage structure, enhanced efficiency in element insertion and query, improved storage space utilization, and reduced likelihood of false positives. Consequently, the PSBF presents a novel approach to the dynamic extensibility of bloom filters. [ABSTRACT FROM AUTHOR]

The Victorian Government Inquiry into wildfires that killed 173 people in 2009 has driven an Australian policy shift from self-evacuation or staying and defending a well-prepared property ('go or stay') to self-evacuation under catastrophic fire weather ('leave early'). The Inquiry also led to the establishment of national 'performance standards' for Private Fire Shelters (PFSs, that are also known as bunkers). Nonetheless, the incorporation of PFSs into national bushfire policy remains embryonic, with only Victoria having streamlined accreditation and planning approval processes. Arguments against PFSs include potentially engendering complacency about preparing dwellings to survive fire and encouraging risky behaviour in response to a fire threat. Counteracting these arguments is research that shows that residents without PFSs have low engagement with bushfire preparation and typically delay evacuation. In any case, because wildfire is unpredictable, it is accepted that self-evacuation plans must have fallback positions that include sheltering 'in place' from the bushfire, making properly used and well-maintained PFSs an important element of bushfire safety. A less discussed barrier to PFS uptake outside Victoria appears to hinge on a lack of clarity about obligations for their design, certification, and consistency with planning approvals. The escalating Australian fire crisis demands much greater research and development in legal frameworks, policy and planning processes for PFSs, as well as design and construction standards. Progress in enhancing Australian laws and policies on this issue may offer important opportunities for other jurisdictions that will experience similar challenges as climate change intensifies fire regimes around the world. [ABSTRACT FROM AUTHOR]

The decarbonisation policies for the EU building stock can improve living conditions, including thermal comfort and lower energy bills. However, these measures may impose financial burdens on low-income households, reducing their disposable income and exacerbating their vulnerability. The current study investigates the impact of decarbonisation policies on the EU's building stock, with a specific focus on Minimum Energy Performance Standards (MEPS), the new Emissions Trading System (ETS2) for buildings, and the phase-out of fossil heating systems. By employing a linear, static latest version of Microsoft Excel (Microsoft 365)-based model and analyzing Eurostat data, this study quantifies the effects of these policies on energy consumption, costs, and necessary investments. Moreover, the study emphasizes their implications for low-income groups using vulnerability indicators. The findings demonstrate that a combination of MEPs, ETS2, and phasing out fossil heating systems effectively reduces energy consumption and costs across most countries. However, implementing ETS2 alone may lead to energy reduction and discomfort for low-income groups without addressing underlying demand-side issues. To address this, this study recommends the implementation of more ambitious MEPs or the provision of additional funding alongside ETS2. The phase-out of fossil fuel boilers emerges as the most cost-effective measure in the medium to long term. While MEPS and the phase-out of fossil fuel boilers improve living conditions, they also impose upfront cost burdens and reduce disposable income for low-income households. Therefore, high subsidy rates and supportive policies are necessary to ensure equitable access to investments. The main recommendations include (a) shifting financing to renewable heating systems for low-income households by 2025, addressing cost issues and policies favouring gas boilers; (b) implementing high-funding rate subsidies for energy efficiency in low-income households before 2025, with technical guidance; (c) prioritising the Energy Efficiency First principle in planning to avoid additional emissions or higher costs for low-income households; and (d) considering the energy behaviour of low-income groups in regulations, employing a combination of policies to achieve desired outcomes and ensure thermal comfort. [ABSTRACT FROM AUTHOR]

The growing use of renewable energy sources and sustainable technologies has increased the attractiveness of low-voltage DC distribution grids. Despite initial research and standardization work, the definition of power quality (PQ) issues and their related compatibility levels in DC grids and the related measurement techniques remain in their infancy. The lack of available measurement results obtained in real-world situations is a major shortcoming. In this paper, the results of a measurement campaign obtained in a configurable bipolar 350 V/700 V DC microgrid in an urban environment are presented. Voltage and current signals were registered continuously at different positions in the microgrid with a sampling rate of 500 kSa/s while changing the configuration of the microgrid; the resulting data were analyzed afterwards, with a focus on DC voltage and current variation, ripple, and spectral analysis. The measurements were taken with custom-designed metrology-sound measurement equipment. The measurement results provide input to the development of DC PQ analysis tools and the standardization of DC PQ measurement methods. Furthermore, the experience obtained will be beneficial for utility companies and regulatory authorities for reliable planning-level and compatibility-level surveys. [ABSTRACT FROM AUTHOR]

This study evaluated the diagnostic value of a rapid whole-body fluorodeoxyglucose (FDG) positron emission tomography (PET)/magnetic resonance imaging (MRI) approach, combining Bayesian penalised likelihood (BPL) PET with an optimised β value and abbreviated MRI (abb-MRI). The study compares the diagnostic performance of this approach with the standard PET/MRI that utilises ordered subsets expectation maximisation (OSEM) PET and standard MRI (std-MRI). The optimal β value was determined by evaluating the noise-equivalent count (NEC) phantom, background variability, contrast recovery, recovery coefficient, and visual scores (VS) for OSEM and BPL with β100–1000 at 2.5-, 1.5-, and 1.0-min scans, respectively. Clinical evaluations were conducted for NECpatient, NECdensity, liver signal-to-noise ratio (SNR), lesion maximum standardised uptake value, lesion signal-to-background ratio, lesion SNR, and VS in 49 patients. The diagnostic performance of BPL/abb-MRI was retrospectively assessed for lesion detection and differentiation in 156 patients using VS. The optimal β values were β600 for a 1.5-min scan and β700 for a 1.0-min scan. BPL/abb-MRI at these β values was equivalent to OSEM/std-MRI for a 2.5-min scan. By combining BPL with optimal β and abb-MRI, rapid whole-body PET/MRI could be achieved in ≤1.5 min per bed position, while maintaining comparable diagnostic performance to standard PET/MRI. [ABSTRACT FROM AUTHOR]

As a part of the World Meteorological Organization (WMO) Global Observing System, HIRAS-1 and HIRAS-2's observations' impact on improving the accuracy of numerical weather prediction (NWP) can be summarized into two questions: (1) Will HIRAS observation help the NWP system to improve its accuracy? (2) Which instrument has the greater impact on NWP? To answer the questions, four experiments are designed here: (I) the HIRAS-1 experiment, which assimilates the principal component (PC) scores derived from HIRAS-1 radiance observation from the FY-3D satellite; (II) the HIRAS-2 experiment, which assimilates HIRAS-2 (onboard the FY-3E satellite) radiance-observation-derived PC scores; (III) the J-01 experiment, which assimilates JPSS1 CrIS radiance-observation-derived PC scores; (IV) the control experiment. Each experiment generated a series of forecasts with 24 h lead-time from 16 March 2022 to 12 April 2022 using the Unified Forecast System Short-Range Weather application. Forecast evaluation using radiosonde and aircraft observation reveals: (a) for upper-level variables (i.e., temperature and specific humidity), assimilating HIRAS observation can improve the NWP's performance by decreasing the standard deviation (Stdev) and increasing the anomaly correlation coefficient (ACC); (b) according to the multi-category Heidke skill score, HIRAS assimilation experiments, especially the HIRAS-2 experiment, have a higher agreement with hourly precipitation observations; (c) based on two tornado-outbreak case studies, which occurred on 30 March 2022 and 5 April 2022, HIRAS observation can increase the predicted intensity of 0–1 km storm relative helicity and decrease the height of the lifted condensation level at tornado outbreak locations; and (d) compared to CrIS, HIRAS-2 still has room for improvement. [ABSTRACT FROM AUTHOR]

This paper presents an analysis of the IEEE 802.11ax networks' coexistence with legacy stations, namely IEEE 802.11ac, IEEE 802.11n, and IEEE 802.11a. The IEEE 802.11ax standard introduces several new features that can enhance network performance and capacity. The legacy devices that do not support these features will continue to coexist with newer devices, creating a mixed network environment. This usually leads to a deterioration in the overall performance of such networks; therefore, in the paper, we want to show how we can reduce the negative impact of legacy devices. In this study, we investigate the performance of mixed networks by applying various parameters to both the MAC and PHY layers. We focus on evaluating the impact of the BSS coloring mechanism introduced to the IEEE 802.11ax standard on network performance. We also examine the impact of A-MPDU and A-MSDU aggregations on network efficiency. Through simulations, we analyze the typical performance metrics such as throughput, mean packet delay, and packet loss of mixed networks with different topologies and configurations. Our findings indicate that implementing the BSS coloring mechanism in dense networks can increase throughput by up to 43%. We also show that the presence of legacy devices in the network disrupts the functioning of this mechanism. To address this, we recommend using an aggregation technique, which can improve throughput by up to 79%. The presented research revealed that it is possible to optimize the performance of mixed IEEE 802.11ax networks. [ABSTRACT FROM AUTHOR]

Dispersion-inclusive density functional theory (DFT) methods have unequivocally demonstrated improved performances with respect to standard DFT approximations for modeling large and extended molecular systems at the quantum mechanical level. Yet, in some cases, disagreements with highly accurate reference calculations, such as CCSD(T) and quantum Monte Carlo (MC) calculations, still remain. Furthermore, the application of general-purpose corrections, such as the popular Grimme's semi-classical models (DFT-D), to different Kohn–Sham exchange–correlation functionals sometimes leads to variable and inconsistent results, which recommend a careful prior evaluation. In a recent study, we proposed a simple optimization protocol for enhancing the accuracy of these DFT-D methods by following an alternative and system-specific approach. Here, adopting the same computational strategy, we show how the accurate MC intermolecular interactions of a large set of water clusters of variable sizes (i.e., 300 (H2O)n structures, n = 9, 15, 27) can be reproduced remarkably well by dispersion-corrected DFT models (i.e., B3LYP-D4, PBE-D4, revPBE(0)-D4) upon re-optimization, reaching a mean absolute error per monomer of ~0.1 kcal/mol. Hence, the obtained results support the use of this procedure for fine-tuning tailored DFT-D models for the accurate description of targeted molecular systems. [ABSTRACT FROM AUTHOR]

According to BESO's principle of binarizing continuous design variables and the excellent performance of the standard HPO algorithm in terms of solving continuous optimization problems, a discrete binary Hunter-prey optimization algorithm is introduced to construct an efficient topology optimization model. It was used to solve the problems that the BESO method of topology optimization has, such as easily falling into the local optimal value and being unable to obtain the optimal topology configuration; the metaheuristic algorithm was able to solve the topology optimization model's low computational efficiency and could easily produce intermediate elements and unclear boundaries. Firstly, the BHPO algorithm was constructed by discrete binary processing using the s-shape transformation function. Secondly, BHPO-BESO topology optimization theory was established by combining the BHPO algorithm with BESO topology optimization. Using the sensitivity information of the objective function and the updated principle of the meta-heuristic of the BHPO algorithm, a semi-random search for the optimal topology configuration was carried out. Finally, numerical simulation experiments were conducted by using the three typical examples of the cantilever beam, simply supported beam, and clamping beam as optimization objects and the results were compared with the solution results of BESO topology optimization. The experimental results showed that compared with BESO, BHPO-BESO could find the optimal topology configuration with lower compliance and maximum stiffness, and it has higher computational efficiency, which can solve the above problems. [ABSTRACT FROM AUTHOR]

Thermoelectric generators (TEGs) possess the ability to generate electrical power from heat. As TEGs are operated under a thermal gradient, inhomogeneous material properties—either by design or due to inhomogeneous material degradation under thermal load—are commonly found. However, this cannot be addressed using standard approaches for performance analysis of TEGs in which spatially homogeneous materials are assumed. Therefore, an innovative method of analysis, which can incorporate inhomogeneous material properties, is presented in this study. This is crucial to understand the measured performance parameters of TEGs and, from this, develop means to improve their longevity. The analysis combines experimental profiling of inhomogeneous material properties, modelling of the material properties using a single parabolic band model, and calculation of device properties using the established Constant Property Model. We compare modeling results assuming homogeneous and inhomogeneous properties to the measurement results of an Mg2(Si,Sn)-based TEG prototype. We find that relevant discrepancies lie in the effective temperature difference across the TE leg, which decreases by ~10%, and in the difference between measured and calculated heat flow, which increases from 2–15% to 9–16% when considering the inhomogeneous material. The approach confirms additional resistances in the TEG as the main performance loss mechanism and allows the accurate calculation of the impact of different improvements on the TEG's performance. [ABSTRACT FROM AUTHOR]

The European Commission (EC) has published a European Union (EU) Road Safety Framework for the period 2021 to 2030 to reduce road fatalities. In addition, the EC with the EU Directive 2019/1936 requires a much more detailed recording of road attributes. Therefore, automatic detection of school routes, four classes of crosswalks, and divided carriageways were performed in this paper. The study integrated satellite imagery as a data source and the Yolo object detector. The satellite Pleiades Neo 3 with a spatial resolution of 0.3 m was used as the source for the satellite images. In addition, the study was divided into three phases: vector processing, satellite imagery processing, and training and evaluation of the You Only Look Once (Yolo) object detector. The training process was performed on 1951 images with 2515 samples, while the evaluation was performed on 651 images with 862 samples. For school zones and divided carriageways, this study achieved accuracies of 0.988 and 0.950, respectively. For crosswalks, this study also achieved similar or better results than similar work, with accuracies ranging from 0.957 to 0.988. The study also provided the standard performance measure for object recognition, mean average precision (mAP), as well as the values for the confusion matrix, precision, recall, and f1 score for each class as benchmark values for future studies. [ABSTRACT FROM AUTHOR]

This article addresses the problem of converting a single-objective combinatorial problem into a multi-objective one using the Pareto front approach. Although existing algorithms can identify the optimal solution in a multi-objective space, they fail to satisfy constraints while achieving optimal performance. To address this issue, we propose a multi-objective artificial bee colony optimization algorithm with a classical multi-objective theme called fitness sharing. This approach helps the convergence of the Pareto solution set towards a single optimal solution that satisfies multiple objectives. This article introduces multi-objective optimization with an example of a non-dominated sequencing technique and fitness sharing approach. The experimentation is carried out in MATLAB 2018a. In addition, we applied the proposed algorithm to two different real-time datasets, namely the knapsack problem and the nurse scheduling problem (NSP). The outcome of the proposed MBABC-NM algorithm is evaluated using standard performance indicators such as average distance, number of reference solutions (NRS), overall count of attained solutions (TNS), and overall non-dominated generation volume (ONGV). The results show that it outperforms other algorithms. [ABSTRACT FROM AUTHOR]

Monitoring the evolution of the state of networks is an important issue to ensure that many applications provide the required quality of service. The first step in network-monitoring systems consists of capturing packets; that is, packets arrive at the system through a network interface card and are placed into system memory. Then, in this first stage, and usually in relation to the operating system, packets are treated and transferred from the capturing buffer to a higher-layer processing, for instance, to be analyzed in the next step of the system. In this work, we focus on the capturing stage. In particular, we focus on a Linux packet-capturing system. We model it as a single server queue. Taking into account that the server can be in charge not only of the capturing process but also of other tasks, we consider that the queue has vacations, i.e., there is some time when the capturing process cannot be carried out. We also assume that the queue has a finite buffer. We consider three different models and present a rigorous analysis of the derived Markov chain of each of the models. We provide standard performance metrics in all cases. We also evaluate the performance of these models in a real packet-capture probe. [ABSTRACT FROM AUTHOR]

A recommender system not only "gains users' confidence" but also helps them in other ways, such as reducing their time spent and effort. To gain users' confidence, one of the main goals of recommender systems in an e-commerce industry is to estimate the users' interest by tracking the users' transactional behavior to provide a fast and highly related set of top recommendations out of thousands of products. The standard ranking-based models, i.e., the denoising auto-encoder (DAE) and collaborative denoising auto-encoder (CDAE), exploit positive-only feedback without utilizing the ratings' ranks for the full set of observed ratings. To confirm the rank of observed ratings (either low or high), a confidence value for each rating is required. Hence, an improved, confidence-integrated DAE is proposed to enhance the performance of the standard DAE for solving recommender systems problems. The correctness of the proposed method is authenticated using two standard MovieLens datasets such as ML-1M and ML-100K. The proposed study acts as a vital contribution for the design of an efficient, robust, and accurate algorithm by learning prominent latent features used for fast and accurate recommendations. The proposed model outperforms the state-of-the-art methods by achieving improved P@10, R@10, NDCG@10, and MAP scores. [ABSTRACT FROM AUTHOR]

Fire accidents are a significant risk to human life and civil infrastructure. As a countermeasure, the regulatory bodies of different countries have established standards for evaluating the performance of construction elements during fire exposure. ISO 834 is the globally accepted fire-resistance testing standard. Other standards include ASTM E119, BS 476, IS 3809, JIS A 1304, AS 1503, EN 1363, and GB/T 9978, which are utilized by the US, Britain, India, Japan, Australia, Europe, and China, respectively. This article presents a summary and comparison of the fire-resistance testing standards. In reality, standard tests for isolated structural members may not efficiently portray realistic fire scenarios due to the fire location, its intensity, etc. Thus, researchers have utilized a variety of specialized setups and full-scale non-standard fire tests to fulfill their research objectives. The article includes a summary of selected full-scale, ad hoc, and specialized setups that were reported in the literature. The article highlights the need for timely updates of fire standards to accommodate the testing of newly developed construction materials, structural systems, and possible regional fire scenarios. The article also identifies the research areas that require significant focus in experimental structural fire-resistant testing. [ABSTRACT FROM AUTHOR]

In this work, the contrast source inversion method is combined with a finite element method to solve microwave imaging problems. The paper's major contribution is the development of a novel contrast source variable discretization that leads to simplify the algorithm implementation and, at the same time, to improve the accuracy of the discretized quantities. Moreover, the imaging problem is recreated in a synthetic environment, where the antennas, and their corresponding coaxial port, are modeled. The implemented algorithm is applied to reconstruct the tissues' dielectric properties inside the head for brain stroke microwave imaging. The proposed implementation is compared with the standard one to evaluate the impact of the variables' discretization on the algorithm's accuracy. Furthermore, the paper shows the obtained performances with the proposed and the standard implementations of the contrast source inversion method in the same realistic 3D scenario. The exploited numerical example shows that the proposed discretization can reach a better focus on the stroke region in comparison with the standard one. However, the variation is within a limited range of permittivity values, which is reflected in similar averages. [ABSTRACT FROM AUTHOR]

Ionospheric scintillation is one of the main error sources of Global Navigation Satellite System (GNSS) positioning. The presence of scintillation may result in cycle slips, measurement errors or even losses of lock on satellites, eventually leading to complete failure of positioning. Typically, scintillation parameters S4 and σϕ are used to characterize amplitude and phase scintillation, respectively. However, the scintillation parameters can only be generated from data with a frequency of at least 1 Hz. Rate of change of total electron content index (ROTI) is often used as a proxy for scintillation parameters, which can be obtained from 1/30 Hz data. However, previous research has shown the inefficiency of ROTI to represent scintillation. Therefore, the multipath parameter (MP) has been proposed as another proxy for scintillation parameters, which can also be obtained from 1/30 Hz data. In this paper, both MP and ROTI (standard parameters) were used to mitigate scintillation effects on precise point positioning (PPP). To evaluate the effectiveness of MP and ROTI in mitigating scintillation effects, S4 and σϕ were also used for comparison and validation. Three strategies are proposed: (1) remove all observations from the satellite that is most affected by scintillation; (2) remove the scintillation-affected observations; (3) weight the measurement noise matrix in the Kalman Filter (KF) process. The results show that the observation removal and weighting strategies are considerably more effective than the satellite removal strategy. The results also show that the improvement of PPP outputs reaches 93.1% and the performance of standard parameters is comparable to that of scintillation parameters in the observation removal and weighting strategies. [ABSTRACT FROM AUTHOR]

The standard HEVC codec and its extension for coding multiview videos, known as MV-HEVC, have proven to deliver improved visual quality compared to its predecessor, H.264/MPEG-4 AVC's multiview extension, H.264-MVC, for the same frame resolution with up to 50% bitrate savings. MV-HEVC's framework is similar to that of H.264-MVC, which uses a multi-layer coding approach. Hence, MV-HEVC would require all frames from other reference layers decoded prior to decoding a new layer. Thus, the multi-layer coding architecture would be a bottleneck when it comes to quicker frame streaming across different views. In this paper, an HEVC-based Frame Interleaved Stereo/Multiview Video Codec (HEVC-FISMVC) that uses a single layer encoding approach to encode stereo and multiview video sequences is presented. The frames of stereo or multiview video sequences are interleaved in such a way that encoding the resulting monoscopic video stream would maximize the exploitation of temporal, inter-view, and cross-view correlations and thus improving the overall coding efficiency. The coding performance of the proposed HEVC-FISMVC codec is assessed and compared with that of the standard MV-HEVC's performance for three standard multi-view video sequences, namely: "Poznan_Street", "Kendo" and "Newspaper1". Experimental results show that the proposed codec provides more substantial coding gains than the anchor MV-HEVC for coding both stereo and multi-view video sequences. [ABSTRACT FROM AUTHOR]

In this study, a pitch H-infinity control algorithm was developed for variable-speed–variable-pitch (VSVP) wind turbines to improve the rotor standard deviation of the wind turbines under normal and extreme wind conditions. The pitch H-infinity control algorithm only uses H-infinity control in the blade pitch control loop in the rated power region, and conventional torque gain scheduling algorithms are applied in the partial power region. The performance of this controller was verified using simulations of a 5 MW wind turbine using the commercial aeroelastic simulation code Bladed. The performance of the pitch H-infinity controller was compared with that of the conventional proportional-integral (PI) control algorithm under three different operating conditions: normal operating conditions without sensor noise, normal operating conditions with sensor noise, and extreme operating conditions without sensor noise based on the wind turbine design standard by IEC. Based on the simulation results with two different wind speed regions, namely, the transition region and the rated power region, it was found that the proposed pitch H-infinity controller showed better rotor speed standard deviation performance in the three operating conditions and achieved lower standard deviations of the rotor speed and the electrical power without affecting the mean electrical power. [ABSTRACT FROM AUTHOR]

The solar simulator has allowed all photovoltaic devices to be developed and tested under laboratory conditions. Filtered xenon arc lamps were the gold-standard source for solar simulation of small-area silicon photovoltaic devices; however, scaling these devices to illuminate large areas is neither efficient nor practical. Large-area solar simulation to meet appropriate spectral content and spatial nonuniformity of irradiance (SNI) standards has traditionally been difficult and expensive to achieve, partly due to the light sources employed. LED-based solar simulation allows a better electrical efficiency and uniformity of irradiance while meeting spectral intensity requirements with better form factors. This work details the design based on optical modeling of a scalable, large-area, LED-based, solar simulator meeting Class AAA performance standards formed for inline testing of printed solar cells. The modular design approach employed enables the illuminated area to be expanded in quanta of ~260 cm2 to any preferred illumination area. A 640 cm2 area illuminated by two adjacent PCB units has a measured total emission of 100 mW/cm2, with a SNI of 1.7% and an excellent approximation to the AM1.5G spectrum over the wavelength range of 350–1100 nm. The measured long-term temporal instability of irradiance (TIE) is <0.5% for a 550-min continuous run. This work identifies the design steps and details the development and measurement of a scalable large-area LED-based solar simulator of interest to the PV testing community, and others using solar simulators. [ABSTRACT FROM AUTHOR]

The primary means for electronic position fixing in use in contemporary maritime transport are shipborne GPS (Global Positioning System) receivers or DGPS (Differential GPS) receivers. More advanced GNSS (Global Navigation Satellite System) or RNSS (Regional Navigation Satellite Systems) receivers are able to process combined signals from American GPS, Russian GLONASS, Chinese Beidou (BDS), European Galileo, Indian IRNSS, and Japan QZSS. Satellite-based augmentation systems (SBAS) are still not commonly used in the maritime domain, especially onboard vessels certified under international SOLAS convention. The issues and weaknesses of existing International Maritime Organization recommendations, guidelines, requirements, performance standards, and policies on GNSS shipborne sensors are discussed and presented in the paper. Many problems that have already been dealt with in other means of transportation are still to be solved in the maritime domain. The integrity monitoring is addressed as the main issue, and recommendations based on solutions implemented in aviation and the latest research are proposed. Finally, the strengths, weaknesses, opportunities, and threats awaiting maritime GNSS standardization process are outlined. [ABSTRACT FROM AUTHOR]

In the Atacama Desert, the spectral distribution of solar radiation differs from the global standard, showing very high levels of irradiation with a particularly high ultraviolet content. Additionally, the response of photovoltaic (PV) technologies is spectrally dependent, so it is necessary to consider local conditions and type of technology to optimize PV devices since solar cells are usually designed for maximum performance under standard testing conditions (STC). In this work, we determined geometrical and doping parameters to optimize the power of an n-type bifacial passivated emitter and rear totally diffused solar cell (n-PERT). Six parameters (the thicknesses of cell, emitter, and back surface field, as well as doping concentration of emitter, base, and back surface field) were used to optimize the cell under the Atacama Desert spectrum (AM 1.08) and under standard conditions (AM 1.5) through a genetic algorithm. To validate the model, the calculated performance of the n-PERT cell was compared with experimental measurements. Computed and experimental efficiencies showed a relative difference below 1% under STC conditions. Through the optimization process, we found that different geometry and doping concentrations are necessary for cells to be used in the Atacama Desert. Reducing the thickness of all layers and increasing doping can lead to a relative increment of 5.4% in the cell efficiency under AM 1.08. Finally, we show the potential effect of metallization and the viability of reducing the thicknesses of the emitter and the back surface field. [ABSTRACT FROM AUTHOR]

Energy renovations of the building stock are a paramount objective of the European Union (EU) to combat climate change. A tool for renovation progress monitoring is energy performance certificate (EPC) labelling. The present study tested the effect of different EPC label classifications on a national database, which comprises ~25,000 EPC values from apartment buildings, detached houses, office buildings, and educational, commercial, and service buildings. Analysing the EPC classes labelling resulting from four different EU methods, we estimated the annual renovation rates, costs, energy savings, and CO2 emissions reduction that would affect the national building stock if each of them was adopted, to fulfil the European Climate Target Plan by the year 2033. The ISO 52003-1:2017 two-point and one-point methods determined a very uneven distribution of renovation rates, from 0.45% to ~9%. Conversely, the Directive 15% recently proposed in COM/2021/802 with uniform rates determined smaller differences and standard deviation, not pushing renovations above 3.70%, namely a rate that once fine-tuned can stimulate realistic, yet effective renovation campaigns. The major differences in renovation rates provided by the studied methods show the need for a harmonized strategy such as the Directive proposal to enable achievement of European targets. [ABSTRACT FROM AUTHOR]

The quantum computer has been claimed to show more quantum advantage than the classical computer in solving some specific problems. Many companies and research institutes try to develop quantum computers with different physical implementations. Currently, most people only focus on the number of qubits in a quantum computer and consider it as a standard to evaluate the performance of the quantum computer intuitively. However, it is quite misleading in most times, especially for investors or governments. This is because the quantum computer works in a quite different way than classical computers. Thus, quantum benchmarking is of great importance. Currently, many quantum benchmarks are proposed from different aspects. In this paper, we review the existing performance benchmarking protocols, models, and metrics. We classify the benchmarking techniques into three categories: physical benchmarking, aggregative benchmarking, and application-level benchmarking. We also discuss the future trend for quantum computer's benchmarking and propose setting up the QTOP100. [ABSTRACT FROM AUTHOR]

The development of a hydrogen energy-based society is becoming the solution for more and more countries. Fuel cell electric vehicles are the best carriers for developing a hydrogen energy-based society. The current research on hydrogen leakage and the diffusion of fuel cell electric vehicles has been sufficient. However, the study of hydrogen safety has not reduced the safety concerns for society and government management departments, concerning the large-scale promotion of fuel cell electric vehicles. Hydrogen safety is both a technical and psychological issue. This paper aims to provide a comprehensive overview of fuel cell electric vehicles' hydrogen dispersion and the burning behavior and introduce the relevant work of international standardization and global technical regulations. The CFD simulations in tunnels, underground car parks, and multistory car parks show that the hydrogen escape performance is excellent. At the same time, the research verifies that the flow, the direction of leakage, and the vehicle itself are the most critical factors affecting hydrogen distribution. The impact of the leakage location and leakage pore size is much smaller. The relevant studies also show that the risk is still controllable even if the hydrogen leakage rate is increased ten times the limit of GTR 13 to 1000 NL/min and then ignited. Multi-vehicle combustion tests of fuel cell electric vehicles showed that adjacent vehicles were not ignited by the hydrogen. This shows that as long as the appropriate measures are taken, the risk of a hydrogen leak or the combustion of fuel cell electric vehicles is controllable. The introduction of relevant standards and regulations also indirectly proves this point. This paper will provide product design guidelines for R&D personnel, offer the latest knowledge and guidance to the regulatory agencies, and increase the public's acceptance of fuel cell electric vehicles. [ABSTRACT FROM AUTHOR]

This paper addresses the energy efficiency issue in household appliances, which has led to the establishment of policies at a global level in favor of setting minimum energy performance standards (MEPS), which guarantee end users are able to select more efficient equipment. The countries of the United States, Brazil, Mexico, Chile, and the Community of the European Union were taken as references to review their policies and implementation strategies, in order to be compared with the Colombian panorama (at the market, technical and political levels). This allows the establishment of common aspects and differences related to the determination of energy consumption, adjusted volume, and formalization of efficiency ranges, and in the specific case of domestic refrigeration. Managing to distinguish the most relevant aspects for the successful adoption of these policies in Colombia. It is evident that the implementation of these guidelines has a positive impact on the market of the countries and communities of reference. Similarly, the MEPS are shown as a mechanism to regulate energy consumption in the residential sector. [ABSTRACT FROM AUTHOR]

Background: During the last two years, a variety of assays for the serological detection of antibodies to the new SARS-CoV-2 virus have been launched and used as part of standard care in many laboratories. The pace with which these tests have been introduced into routine care emphasizes the importance of quality measures for analytical methods, particularly with regard to the implications of results for clinical and epidemiologic decisions. Accuracy, reliability and comparability of analytical test results are thus essential, and here external quality assessment (EQA) is the most important quality assurance tool. It allows us to achieve harmonization of test methods as a prerequisite for a high standard of performance for laboratory and analytical techniques and their interpretation. Methods: This EQA scheme consisted of pre-characterized clinical biospecimens dedicated to the analysis of anti-SARS-CoV-2 IgG total antibodies and differentiation into spike protein-specific IgG antibodies against SARS-CoV-2 (anti-S-SARS-CoV-2) and nucleocapsid-specific IgG antibodies against SARS-CoV-2 (anti-N-SARS-CoV-2). Results: A total of 239 laboratories across Europe participated in this scheme, called CoVimm. In detail, 536 results for anti-SARS-CoV-2 IgG, 431 results for anti-S-SARS-CoV-2 IgG, and 200 results for anti-N-SARS-CoV-2 IgG were reported. Based on the pre-defined thresholds, the success rates for the determination of anti-S-SARS-CoV-2 IgG and anti-N-SARS-CoV-2 IgG were 96% and 90%, respectively. Interestingly, only 64% of the participating laboratories successfully passed the EQA scheme for the determination of total anti-SARS-CoV-2 IgG. Conclusions: This EQA revealed serious concerns regarding the reliability and appropriate use of anti-SARS-CoV-2 antibody assays in routine care. In addition to the wide heterogeneity of different assays used by participating laboratories, a lack of standardization and harmonization is also evident. This is of particular importance for reliable and clinically meaningful interpretation of test results. [ABSTRACT FROM AUTHOR]

Embedded controllers for multivariable processes have become a powerful tool in industrial implementations. Here, the Model Predictive Control offers higher performances than standard control methods. However, they face low computational resources, which reduces their processing capabilities. Based on pipelining concept, this paper presents a new embedded software-based implementation for a constrained Multi-Input-Multi-Output predictive control algorithm. The main goal of this work focuses on improving the timing performance and the resource usage of the control algorithm. Therefore, a profiling study of the baseline algorithm is developed, and the performance bottlenecks are identified. The functionality and effectiveness of the proposed implementation are validated in the NI myRIO 1900 platform using the simulation of a jet transport aircraft during cruise flight and a tape transport system. Numerical results for the study cases show that the latency and the processor usage are substantially reduced compared with the baseline algorithm, 4.6 × and 3.17 × respectively. Thus, efficient program execution is obtained which makes the proposed software-based implementation mainly suitable for embedded control systems. [ABSTRACT FROM AUTHOR]

Most of the methods for real-time semantic segmentation do not take into account temporal information when working with video sequences. This is counter-intuitive in real-world scenarios where the main application of such methods is, precisely, being able to process frame sequences as quickly and accurately as possible. In this paper, we address this problem by exploiting the temporal information provided by previous frames of the video stream. Our method leverages a previous input frame as well as the previous output of the network to enhance the prediction accuracy of the current input frame. We develop a module that obtains feature maps rich in change information. Additionally, we incorporate the previous output of the network into all the decoder stages as a way of increasing the attention given to relevant features. Finally, to properly train and evaluate our methods, we introduce CityscapesVid, a dataset specifically designed to benchmark semantic video segmentation networks. Our proposed network, entitled FASSVid improves the mIoU accuracy performance over a standard non-sequential baseline model. Moreover, FASSVid obtains state-of-the-art inference speed and competitive mIoU results compared to other state-of-the-art lightweight networks, with significantly lower number of computations. Specifically, we obtain 71% of mIoU in our CityscapesVid dataset, running at 114.9 FPS on a single NVIDIA GTX 1080Ti and 31 FPS on the NVIDIA Jetson Nano embedded board with images of size 1024 × 2048 and 512 × 1024 , respectively. [ABSTRACT FROM AUTHOR]

China's first Mars exploration mission, named Tianwen-1, landed on Mars on 15 May 2021. The Mars Surface Composition Detector (MarSCoDe) payload onboard the Zhurong rover applied the laser-induced breakdown spectroscopy (LIBS) technique to acquire chemical compositions of Martian rocks and soils. The quantitative interpretation of MarSCoDe-LIBS spectra needs to establish a LIBS spectral database that requires plenty of terrestrial geological standards. In this work, we selected 316 terrestrial standards including igneous rocks, sedimentary rocks, metamorphic rocks, and ores, whose chemical compositions, rock types, and chemical weathering characteristics were comparable to those of Martian materials from previous orbital and in situ detections. These rocks were crushed, ground, and sieved into powders less than <38 μm and pressed into pellets to minimize heterogeneity at the scale of laser spot. The chemical compositions of these standards were independently measured by X-ray fluorescence (XRF). Subsequently, the LIBS spectra of MAL standards were acquired using an established LIBS system at Shandong University (SDU-LIBS). In order to evaluate the performance of these standards in LIBS spectral interpretation, we established multivariate models using partial least squares (PLS) and least absolute shrinkage and selection (LASSO) algorithms to predict the abundance of major elements based on SDU-LIBS spectra. The root mean squared error (RMSE) values of these models are comparable to those of the published models for MarSCoDe, ChemCam, and SuperCam, suggesting these PLS and LASSO models work well. From our research, we can conclude that these 316 MAL targets are good candidates to acquire geochemistry information based on the LIBS technique. These targets could be regarded as geological standards to build a LIBS database using a prototype of MarSCoDe in the near future, which is critical to obtain accurate chemical compositions of Martian rocks and soils based on MarSCoDe-LIBS spectral data. [ABSTRACT FROM AUTHOR]

This article reviews the basis and the main aspects of the recent evolution of Broadband Power Line Communications (BB-PLC or, more commonly, BPL) technologies. The article starts describing the organizations and alliances involved in the development and evolution of BPL systems, as well as the standardization institutions working on PLC technologies. Then, a short description of the technical foundation of the recent proposed technologies and a comparison of the main specifications are presented; the regulatory activities related to the limits of emissions and immunity are also addressed. Finally, some representative applications of BPL and some selected use cases enabled by these technologies are summarized, together with the main challenges to be faced. [ABSTRACT FROM AUTHOR]

Recently, various types of in vitro-reconstructed 3D skin models have been developed for drug testing and disease modeling. Herein, we structurally and functionally validated a self-assembled reconstructed skin equivalent (RSE) and developed an IL-17a-induced in vitro psoriasis-like model using a self-assembled RSE. The tissue engineering approach was used to construct the self-assembled RSE. The dermal layer was generated using fibroblasts secreting their own ECM, and the epidermal layer was reconstructed by seeding keratinocytes on the dermal layer. To generate the psoriatic model, IL-17A was added to the culture medium during the air–liquid interface culture period. Self-assembled RSE resulted in a fully differentiated epidermal layer, a well-established basement membrane, and dermal collagen deposition. In addition, self-assembled RSE was tested for 20 reference chemicals according to the Performance Standard of OECD TG439 and showed overall sensitivity, specificity, and accuracy of 100%, 90%, and 95%, respectively. The IL-17a-treated psoriatic RSE model exhibited psoriatic epidermal characteristics, such as epidermal hyperproliferation, parakeratosis, and increased expression of KRT6, KRT17, hBD2, and S100A9. Thus, our results suggest that a self-assembled RSE that structurally and functionally mimics the human skin has a great potential for testing various drugs or cosmetic ingredients and modeling inflammatory skin diseases. [ABSTRACT FROM AUTHOR]

Background: The human microbiome can contribute to pathogeneses of many complex diseases by mediating disease-leading causal pathways. However, standard mediation analysis methods are not adequate to analyze the microbiome as a mediator due to the excessive number of zero-valued sequencing reads in the data and that the relative abundances have to sum to one. The two main challenges raised by the zero-inflated data structure are: (a) disentangling the mediation effect induced by the point mass at zero; and (b) identifying the observed zero-valued data points that are not zero (i.e., false zeros). Methods: We develop a novel marginal mediation analysis method under the potential-outcomes framework to address the issues. We also show that the marginal model can account for the compositional structure of microbiome data. Results: The mediation effect can be decomposed into two components that are inherent to the two-part nature of zero-inflated distributions. With probabilistic models to account for observing zeros, we also address the challenge with false zeros. A comprehensive simulation study and the application in a real microbiome study showcase our approach in comparison with existing approaches. Conclusions: When analyzing the zero-inflated microbiome composition as the mediators, MarZIC approach has better performance than standard causal mediation analysis approaches and existing competing approach. [ABSTRACT FROM AUTHOR]

X-band radars are in growing use for various oceanographic purposes, providing spatial real-time information about sea state parameters, surface elevations, currents, and bathymetry. Therefore, it is very appealing to use such systems as operational aids to harbour management. In an installation of such a remote sensing system in Haifa Port, consistent radially aligned spikes of brightness randomly distributed with respect to azimuth were identified. These streak noise patterns were found to be interfering with the common approach of oceanographic analysis. Harbour areas are regularly frequented with additional electromagnetic transmissions from other ship and land-based radars, which may serve as a source of such interference. A new approach is proposed for the filtering of such undesirable interference patterns from the X-band radar images. It was verified with comparison to in-situ measurements of a nearby wave buoy. Regardless of the actual source of the corresponding pseudo-wave energy, it was found to be crucial to apply such filtration in order to improve the performance of the standard oceanographic parameter retrieval algorithm. This results in better estimation of the mean sea state parameters towards lower values of the significant wave height. For the commercial WaMoSII system this enhancement was clearly apparent in the improvement of the built-in quality control criteria marks. The developed prepossessing procedure improves the robustness of the directional spectra estimation practically eliminating pseudo-wave energy components. It also extends the system's capability to measure storm events earlier on, a fact that is of high importance for harbour operational decision making. [ABSTRACT FROM AUTHOR]

Industry 4.0 is a new paradigm of digitalization and automation that demands high data rates and real-time ultra-reliable agile communication. Industrial communication at sub-6 GHz industrial, scientific, and medical (ISM) bands has some serious impediments, such as interference, spectral congestion, and limited bandwidth. These limitations hinder the high throughput and reliability requirements of modern industrial applications and mission-critical scenarios. In this paper, we critically assess the potential of the 60 GHz millimeter-wave (mmWave) ISM band as an enabler for ultra-reliable low-latency communication (URLLC) in smart manufacturing, smart factories, and mission-critical operations in Industry 4.0 and beyond. A holistic overview of 60 GHz wireless standards and key performance indicators are discussed. Then the review of 60 GHz smart antenna systems facilitating agile communication for Industry 4.0 and beyond is presented. We envisage that the use of 60 GHz communication and smart antenna systems are crucial for modern industrial communication so that URLLC in Industry 4.0 and beyond could soar to its full potential. [ABSTRACT FROM AUTHOR]

Airway clearance refers to the clearing of any airway blockage caused due to foreign objects such as mud, gravel, and biomaterials such as blood, vomit, or teeth fragments using the technology of choice, portable suction devices. Currently available devices are either too heavy and bulky to be carried, or insufficiently powered to be useful despite being in accordance with the ISO 10079-1 standards. When applied to portable suction, the design and testing standards lack clinical relevancy, which is evidenced by how available portable suction devices are sparingly used in pre-hospital situations. Lack of clinical relevancy despite being in accordance with design/manufacturing standards arise due to little if any collaboration between those developing clinical standards and the bodies that maintain design and manufacturing standards. An updated set of standards is required that accurately reflects evidence-based requirements and specifications, which should promote valid, rational, and relevant engineering designs and manufacturing standards in consideration of the unique scenarios facing prehospital casualty care. This paper aims to critically review the existing standards for portable suction devices and propose modifications based on the evidence and requirements, especially for civilian prehospital and combat casualty care situations. [ABSTRACT FROM AUTHOR]

This paper presents the challenges of increasing the energy efficiency investments in European Union (EU) residential buildings in the context of achieving climate neutrality by 2050. The paper presents the results of the PRIMES buildings model in key energy policy applications to support cost-effective and fair policy making in buildings across Europe. The model covers, in detail, the building sector for all the EU Member States (MS), segmenting the buildings into many categories. The approach proposed includes non-market barriers in conventional microeconomic modelling, which combined with idiosyncratic preferences can capture poor energy efficiency choices and still represent rational behaviours. The model includes a detailed portrayal of policies specific to the sector, comprising economic and regulatory policies as well as institutional measures. The results of the model show that the removal of non-market barriers is of great importance in reducing energy consumption and increasing both the pace and the depth of renovation investment. However, the institutional measures alone are not enough to induce energy efficiency improvement to the scale required to achieve the climate neutrality objectives. Economic (i.e., subsidies) or regulatory measures (i.e., energy performance standards) are also required to decrease emissions and energy consumption in buildings and the paper compares different configurations thereof. The optimum policy mix obviously derives from a compromise among various aims including the cost-effectiveness of the policy budget and the distributional impacts across building and consumer types. [ABSTRACT FROM AUTHOR]

The unbalanced distribution of taxi passengers in space and time affects taxi driver performance. Existing research has studied taxi driver performance by analyzing taxi driver strategies when the taxi is occupied. However, searching for passengers when vacant is costly for drivers, and it limits operational efficiency and income. Few researchers have taken the costs during vacant status into consideration when evaluating taxi driver performance. In this paper, we quantify taxi driver performance using the taxi's average efficiency. We propose the concept of a high-efficiency single taxi trip and then develop a quantification and evaluation model for taxi driver performance based on single trip efficiency. In a case study, we first divide taxi drivers into top drivers and ordinary drivers, according to their performance as calculated from their GPS traces over a week, and analyze the space-time distribution and operating patterns of the top drivers. Then, we compare the space-time distribution of top drivers to ordinary drivers. The results show that top drivers usually operate far away from downtown areas, and the distribution of top driver operations is highly correlated with traffic conditions. We compare the proposed performance-based method with three other approaches to taxi operation evaluation. The results demonstrate the accuracy and feasibility of the proposed method in evaluating taxi driver performance and ranking taxi drivers. This paper could provide empirical insights for improving taxi driver performance. [ABSTRACT FROM AUTHOR]

A frequently reported finding is that general mental ability (GMA) is the best single psychological predictor of job performance. Furthermore, specific abilities often add little incremental validity beyond GMA, suggesting that they are not useful for predicting job performance criteria once general intelligence is accounted for. We review these findings and their historical background, along with different approaches to studying the relative influence of g and narrower abilities. Then, we discuss several recent studies that used relative importance analysis to study this relative influence and that found that specific abilities are equally good, and sometimes better, predictors of work performance than GMA. We conclude by discussing the implications of these findings and sketching future areas for research. [ABSTRACT FROM AUTHOR]