Let A be a non-commutative prime ring with involution ∗ , of characteristic ≠ 2 (and 3) , with Z as the center of A and Π a mapping Π : A → A such that [ Π (x) , x ] ∈ Z for all (skew) symmetric elements x ∈ A. If Π is a non-zero CE-Jordan derivation of A , then A satisfies s 4 , the standard polynomial of degree 4. If Π is a non-zero CE-Jordan ∗-derivation of A , then A satisfies s 4 or Π (y) = λ (y − y *) for all y ∈ A , and some λ ∈ C , the extended centroid of A. Furthermore, we give an example to demonstrate the importance of the restrictions put on the assumptions of our results. [ABSTRACT FROM AUTHOR]