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Marine dynamic disasters, such as storm surges and huge waves, can cause large economic and human losses. The assessment of marine dynamic disasters is, thus, important, but improvements to its reliability are needed. The current study improved and integrated the assessment from the perspective of multi-factor coupling. Using a weighted index system, a marine dynamic disaster assessment indicator system suitable for China's coastal waters was established, and a method for calculating the weight of disaster indicators was proposed from the perspective of rapid assessment. To reduce the assessment deviation in coastal waters, a multi-factor coupling algorithm was proposed. This algorithm obtained amplitude variations of wave orbital motion in horizontal and vertical directions, which was used to evaluate the influence of background current and terrain slope on coastal ocean waves. Landsat 8 remote sensing images were used to carry out an object-oriented extraction of raft and cage aquaculture areas in China's coastal waters. The aquaculture density was then used as the main basis for a vulnerability assessment. Finally, the whole assessment system was integrated and verified during a typical storm surge process in coastal waters around the Shandong Peninsula in China. The coupled variations were also added to the assessment process and increased the risk value by an average of 12% in the High Sea States of the case study. [ABSTRACT FROM AUTHOR]

Haze is the phenomenon of visibility degradation caused by extinction effects related to the physicochemical properties of atmospheric particulate matter (APM). Atmosphere heterogeneous reactions can alter the physicochemical properties of APM. Therefore, it is important to understand the atmospheric heterogeneous reactions of APM in order to reveal the cause of haze. Herein, the current situation, developmental trend, source, and composition of APM pollution in China are reviewed. Additionally, we introduce the reaction characteristics and key chemical processes of common inorganic, organic, and mixed pollutant gases on the surface of mineral particles. The effects of mineral particulate matter on aggregation, regulation, and catalysis in the formation of atmospheric aerosols and the synergistic reaction mechanism of SO2, NO2, O3, and VOCs on the surfaces of different mineral particles are summarized. The problems existing in the current research on heterogeneous reactions on the surfaces of mineral particles are also evaluated. This paper aims to gain a deep understanding of the mechanism of mineral particulate matter promoting the formation of secondary aerosols and attempts to provide theoretical support for effective haze control. [ABSTRACT FROM AUTHOR]

For improved prevention and reduction of marine disasters, China's marine authorities and emergency response agencies require a solution that provides risk assessment, early warning, and decision-making support. This paper proposes a comprehensive approach to disaster assessment that involves automated long-term operation, a spatial information visualization method and systematic integration. The proposed approach provides functions for numerical ocean models with forecast results, automated processing of massive data, multiple disaster/element coupled assessment, and multidimensional display and expression. With regard to storm surge disasters, the approach proposed in this paper adopts a four-tier structure and the functions of each tier are described separately. The original data are comprised of a combination of statistical analysis data and real-time data obtained from the unstructured grid Finite Volume Community Ocean Model. Automated data processing methods and assessment theories incorporating an indicator system and weighted parameters are used for the assessment. By applying 2D/3D visualization technology, assessment results are displayed via several modes for ease of operation and comprehension. The validity of the approach was verified by applying it to Typhoon Hato (No. 1713). Compared with the results of the post-disaster investigation, the assessment results of the proposed approach proved the reliability of the system. [ABSTRACT FROM AUTHOR]

Simple Summary: It has been widely acknowledged in farm animals that environmental heat stress would have comprehensive influences on many kinds of physiological aspects, including the metabolic characteristics, production performances, welfare concerns, etc. The rabbit is a small herbivore and needs to regulate the body temperature in a fine mechanism. Little is known, however, about the genes and pathways that are involved in the regulatory responses under chronic heat stress conditions. In the present study, we investigated the liver transcriptome changes in response to chronic heat stress for Hyla rabbit, that is a commercial meat breed recently introduced into China. We successfully revealed the differentially expressed genes that were significantly enriched in heat stress related biological processes. The results would help us for better understanding the molecular mechanisms underlying physiological responses against heat stress in rabbits. Rabbit is an economically important farm animal in China and also is a widely used animal model in biological researches. Rabbits are very sensitive to the environmental conditions, therefore we investigated the liver transcriptome changes in response to chronic heat stress in the present study. Six Hyla rabbits were randomly divided into two groups: chronic heat stress (HS) and controls without heat stress (CN). Six RNA-Seq libraries totally yielded 380 million clean reads after the quality filtering. Approximately 85.07% of reads were mapped to the reference genome. After assembling transcripts and quantifying gene expression levels, we detected 51 differentially expressed genes (DEGs) between HS and CN groups with thresholds of the adjusted p-value < 0.05 and |log2(FoldChange)| > 1. Among them, 33 and 18 genes were upregulated and downregulated, respectively. Gene ontology analyses further revealed that these DEGs were mainly associated with metabolism of lipids, thyroid hormone metabolic process, and cellular modified amino acid catabolic process. The upregulated ACACB, ACLY, LSS, and CYP7A1 genes were found to be inter-related through biological processes of thioester biosynthetic process, acyl-CoA biosynthetic process, acetyl-CoA metabolic process, and others. Six DEGs were further validated by quantitative real-time PCR analysis. The results revealed the candidate genes and biological processes that will potentially be considered as important regulatory factors involved in the heat stress response in rabbits. [ABSTRACT FROM AUTHOR]

Background: The most effective treatment for end-stage liver diseases is liver transplantation, which is impeded by the shortage of donor livers. Split liver transplantation (SLT) is important for addressing the donor liver shortage. However, full-right full-left SLT for two adult recipients is globally rarely conducted. This study aimed to investigate the clinical outcomes of this technique. Methods: We retrospectively analyzed the clinical data of 22 recipients who underwent full-right full-left SLT at Shulan (Hangzhou) Hospital between January, 2021 and September, 2022. The graft-to-recipient weight ratio (GRWR), cold ischemia time, operation time, length of the anhepatic phase, intraoperative blood loss, and red blood cell transfusion amount were all analyzed. The differences in liver function recovery after transplantation were compared between the left and right hemiliver groups. The postoperative complications and prognosis of the recipients were also analyzed. Results: The livers of 11 donors were transplanted into 22 adult recipients. The GRWR ranged from 1.16–1.65%, the cold ischemia time was 282.86 ± 134.87 min, the operation time was 371.32 ± 75.36 min, the anhepatic phase lasted 60.73 ± 19.00 min, the intraoperative blood loss was 759.09 ± 316.84 mL, and the red blood cell transfusion amount was 695.45 ± 393.67 mL. No significant difference in the levels of liver function markers, total bilirubin, aspartate aminotransferase, or alanine aminotransferase between left and right hemiliver groups at 1, 3, 5, 7, 14, and 28 d postoperatively was observed (both p > 0.05). One recipient developed bile leakage 10 d after transplantation, which improved with endoscopic retrograde cholangiopancreatography-guided nasobiliary drainage and stent placement. Another developed portal vein thrombosis 12 d after transplantation and underwent portal vein thrombectomy and stenting to restore portal vein blood flow. A color Doppler ultrasound performed 2 d after transplantation revealed hepatic artery thrombosis in one patient, and thrombolytic therapy was administered to restore hepatic artery blood flow. The liver function of other patients recovered quickly after transplantation. Conclusions: Full-right full-left SLT for two adult patients is an efficient way to increase the donor pool. It is safe and feasible with careful donor and recipient selection. Transplant hospitals with highly experienced surgeons in SLT are recommended to promote using full-right full-left SLT for two adult recipients. [ABSTRACT FROM AUTHOR]

Figures and Table Graph: Figure 1 (A) The hepatic veins of Segments V and VIII were retained in the right hemiliver and reconstructed with iliac artery. (B) The retrohepatic inferior vena cava (IVC) was divided by longitudinal transection of the front and back walls. (D) Reconstruction of the MHV and IVC in the left hemiliver graft. [Extracted from the article]