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Intraregional spatial variations of satellite-derived anthropogenic nighttime light signals are gradually applied to identify different lighting areas with various socioeconomic activity and urbanization levels when characterizing urbanization dynamics. However, most previous partitioning approaches are carried out at local scales, easily leading to multi-standards of the extracted results from local areas, and this inevitably hinders the comparative analysis on the urbanization dynamics of the large region. Therefore, a partitioning approach considering the characteristics of nighttime light signals at both local and regional scales is necessary for studying spatiotemporal characteristics of urbanization dynamics across the large region using nighttime light imagery. Based on the quadratic relationships between the pixel-level nighttime light brightness and the corresponding spatial gradient for individual cities, we here proposed an improved partitioning approach to quickly identify different types of nighttime lighting areas for the entire region of Southeast Asia. Using the calibrated Defense Meteorological Satellite Program/Operational Line-scan System (DMSP/OLS) data with greater comparability, continuity, and intra-urban variability, the annual nighttime light imagery spanning years 1992–2013 were divided into four types of nighttime lighting areas: low, medium, high, and extremely high, associated with different intensity of anthropogenic activity. The results suggest that Southeast Asia has experienced a rapid and diverse urbanization process from 1992 to 2013. Areas with moderate or low anthropogenic activity show a faster growth rate for the spatial expansion than the developed areas with intense anthropogenic activity. Transitions between different nighttime lighting types potentially depict the trajectory of urban development, the darker areas are gradually transitioning to areas with higher lighting, indicating conspicuous trends of gradually intensified anthropogenic activity from central areas to periphery areas, and from megacities to small cities. Additionally, satellite-derived nighttime lighting areas are in good agreement with the radar-derived human settlements, with dense human settlements in extremely high and high nighttime lighting areas, while sparse human settlements in low nighttime lighting areas. [ABSTRACT FROM AUTHOR]