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In the arid Arabian Peninsula, particularly within the United Arab Emirates (UAE), the perception of rainfall has shifted from a natural blessing to a significant challenge for infrastructure and community resilience. The unprecedented storm on 17 April 2024, exposed critical vulnerabilities in the UAE's urban infrastructure and flood management practices, revealing substantial gaps in handling accumulated precipitation. This study addresses the necessity of updating the Intensity–Duration–Frequency (IDF) curves for the Sharjah Emirate by utilizing recent precipitation data from 2021 to April 2024, alongside previously published 2020 data. By recalibrating the IDF curves based on data from three meteorological stations, this study reveals a substantial increase in rainfall intensities across all durations and return periods. Rainfall intensities increased by an average of 36.76% in Sharjah, 26.52% in Al Dhaid, and 17.55% in Mleiha. These increases indicate a trend towards more severe and frequent rainfall events, emphasizing the urgent need to revise hydrological models and infrastructure designs to enhance flood resilience. This study contributes valuable insights for policymakers, urban planners, and disaster management authorities in the UAE and similar regions worldwide. [ABSTRACT FROM AUTHOR]

Herein, we describe the first consistent regiospecific reaction of isothiocyanates with a variety of substituted N-arylcyanothioformamides in a 1:1 molar ratio to generate a series of imidazolidineiminodithiones decorated with a multitude of functional groups on both aromatic rings. The reaction is carried out at room temperature using a 20 mol% catalytic amount of triethylamine with DMF as the solvent to selectively form the mentioned products with exclusive regioselectivity. The methodology features wide substrate scope, no requirement for chromatography, and good to high reaction yields. The products were isolated by simple ether/brine extraction and the structures were verified by multinuclear NMR spectroscopy and high accuracy mass measurements. The first conclusive molecular structure elucidation of the observed regioisomer was established by single-crystal X-ray diffraction analysis. Likewise, the tautomer of the N-arylcyanothioformamide reactant was proven by X-ray diffraction analysis. Density functional theory computations at the B3LYP-D4/def2-TZVP level in implicit DMF solvent were conducted to support the noted regiochemical outcome and proposed mechanism. [ABSTRACT FROM AUTHOR]

Tung oil (TO) microcapsules (MCs) with a poly(urea-formaldehyde) (PUF) shell were synthesized via one-step in situ polymerization, with the addition of graphene nanoplatelets (GNPs) (1–5 wt. %). The synergistic effects of emulsifiers between gelatin (gel) and Tween 80 were observed, with gel chosen to formulate the MCs due to its enhanced droplet stability. SEM images then displayed an increased shell roughness of the TO-GNP MCs in comparison to the pure TO MCs due to the GNP species on the shell. At the same time, high-resolution transmission electron microscopy (TEM) images also confirmed the presence of GNPs on the outer layer of the MCs, with the stacked graphene layers composed of 5–7 layers with an interlayer distance of ~0.37 nm. Cross-sectional TEM imaging of the MCs also confirmed the successful encapsulation of the GNPs in the core of the MCs. Micromanipulation measurements displayed that the 5% GNPs increased the toughness by 71% compared to the pure TO MCs, due to the reduction in the fractional free volume of the core material. When the MCs were dispersed in an epoxy coating and applied on a metallic substrate, excellent healing capacities of up to 93% were observed for the 5% GNP samples, and 87% for the pure TO MC coatings. The coatings also exhibited excellent corrosion resistance for all samples up to 7 days, with the GNP samples offering a more strenuous path for the corrosive agents. [ABSTRACT FROM AUTHOR]

Extended reality (XR) devices, including virtual and augmented reality head-mounted displays (HMDs), are increasingly utilised within healthcare to provide clinical interventions and education. Currently, XR devices are utilised to assist in reducing pain and improving psychological outcomes for immunocompromised patients in intensive care units, palliative care environments and surgical theatres. However, there is a paucity of research on the risks of infection from such devices in healthcare settings. Identify existing literature providing insights into the infection control risk XR HMDs pose within healthcare facilities and the efficacy of current infection control and cleaning procedures. Three databases (PubMed, Embase and CINAHL) in addition to Google Scholar were systematically searched. A total of seven studies were identified for this review. Microorganisms, including pathogenic bacteria (e.g., Staphylococcus aureus and Pseudomonas aeruginosa), were found to be present on XR HMDs. Published cleaning and infection control protocols designed to disinfect XR HMDs and protect users were heterogeneous in nature. Current cleaning protocols displayed varying levels of efficacy with microbial load affected by multiple factors, including time in use, number of users and XR HMD design features. In healthcare settings, fitting XR HMDs harbouring microorganisms near biological and mucosal entry points presents an infection control risk. An urgent revision of the Spaulding classification is required to ensure flexibility that allows for these devices to be reclassified from 'Non-critical' to 'Semi-Critical' depending on the healthcare setting and patient population (surgery, immunocompromised, burns, etc.). This review identified evidence supporting the presence of microorganisms on XR HMDs. Due to the potential for HMDs to contact mucosal entry points, devices must be re-considered within the Spaulding classification as 'Semi-critical'. The existence of microbial contaminated XR HMDs in high-risk medical settings such as operating wards, intensive care units, emergency departments, labour and delivery wards and clinical areas with immunosuppressed patients requires urgent attention. Public health authorities have a duty of care to develop revised guidelines or new recommendations to ensure efficient sanitation of such devices. [ABSTRACT FROM AUTHOR]

Introduction: Depression in the elderly is an understudied condition. Psychopharmacological and psychotherapeutic approaches suffer from specific difficulties with this patient group. Brain stimulation techniques such as repetitive transcranial magnetic stimulation (rTMS) offer a therapeutic alternative. rTMS remains understudied in this age group when compared with younger patients. Methods: A cohort of 505 patients with depression was analyzed in retrospect concerning their response to rTMS treatment. A total of 15.5% were 60 years old or older, defined as the elderly group of depressed patients. The majority of these were treated with high-frequency protocols over the left dorsolateral prefrontal cortex (DLPFC). For group comparisons, we used Student t-tests or chi-square-tests, depending on the scales of measurement. As measures for effect size, we used Cohen's d for the relative and absolute change in the HDRS total score. Results: Groups did not differ significantly with respect to baseline depression severity or treatment parameters. In the group of elderly patients, a higher number of females were present. Groups did not differ significantly with respect to treatment efficacy, as indicated by the absolute and relative changes in the HDRS-21 sum score. Elderly patients tended to take higher numbers of mood stabilizers. Elderly patients showed a significantly superior reduction for the item "appetite" and a superior reduction tending towards significance for the item "work and interests". Conclusions: Antidepressant rTMS treatment showed comparable efficacy for patients above 60 years to that in younger patients. Differences between the age groups concerning amelioration of distinct HDRS single items deserve further investigation. [ABSTRACT FROM AUTHOR]

The increasing interest in hydrological studies in the United Arab Emirates (UAE) has resulted in the publication of several papers on hydrology and its broad use for addressing contemporaneous challenges confronting humans and the environment in the region. However, for several reasons, these efforts have remained invisible and unrecognized. This paper has reviewed the literature on hydrological research in the UAE to provide a comprehensive source of information for researchers, practitioners, policymakers, and other stakeholders. The documented studies were carefully selected, relying on a bibliometric analysis methodology of five phases to specify the boundary of the study area, adopt the primary keywords for the search, evaluate the obtained papers, exclude the non-conforming ones, and classify the final results into four distinguished topics—namely, rainfall analysis, urban growth and flood hazards, cloud seeding and changing climate, and groundwater situation and utilization. The evaluation process considered assessing the papers' relevancy, authenticity, and coverage of the main issues of interest. In all, a total of 50 published papers were identified based on the specified criteria and reviewed. The main findings were first that the amount of rainfall over the UAE has been declining in the last decade, and this trend is expected to continue, although intensities are rising, suggesting shorter duration events. Secondly, the extensive urban growth in the country has resulted in increasing incidences of urban floods and declining groundwater recharge. Both of these are to be expected as consequences of the increased imperviousness from urbanization and the higher intensities from shorter-duration rainfall events. Thirdly, although the cloud-seeding program has proved to be successful in increasing precipitation amounts, the impact of this on flooding due to more extreme rainfall intensities and on air quality remains worrisome. Finally, groundwater analyses have shown that it is still the main freshwater resource in the country, but its long-term sustainability and quality are being threatened by the declining recharge. This calls for a national policy for groundwater management in the UAE to tackle the challenges associated with the increasing demand for water in all sectors of the economy. The study recommended addressing the gap in the hydrological literature of the UAE, specifically in the field of big meteorological data analysis, the socioeconomic impacts of urban floods, the impacts of climate change in urbanized regions, and the possibility of using alternative resources to recharge groundwater as part of sustainable water management. [ABSTRACT FROM AUTHOR]

Double emulsions (W1/O/W2) have long been used in the food and pharmaceutical industries to encapsulate hydrophobic and hydrophilic drugs and bioactive compounds. This study investigated the effect of different types of emulsifiers (plant- vs. animal-based proteins) on the encapsulation properties of Mentha piperita leaf extract (MLE) prepared using the double emulsion method. Using response surface methodology, the effect of ultrasound-assisted extraction conditions (amplitude 20–50%; time 10–30 min; ethanol concentration 70–90%) on the total phenolic content (TPC) and antioxidant activity (percent inhibition) of the MLE was studied. MLE under optimized conditions (ethanol concentration 76%; amplitude 39%; time 30 min) had a TPC of 62.83 mg GA equivalents/g and an antioxidant activity of 23.49%. The optimized MLE was encapsulated using soy, pea, and whey protein isolates in two emulsifying conditions: 4065× g/min and 4065× g/30 s. The droplet size, optical images, rheology, and encapsulation efficiency (EE%) of the different encapsulated MLEs were compared. The W1/O/W2 produced at 4065× g/min exhibited a smaller droplet size and higher EE% and viscosity than that prepared at 4065× g/30 s. The higher EE% of soy and pea protein isolates indicated their potential as an effective alternative for bioactive compound encapsulation. [ABSTRACT FROM AUTHOR]

Y chromosome short tandem repeat polymorphisms (Y-STRs) are important in many areas of human genetics. Y chromosomal STRs, being normally utilized in the field of forensics, exhibit low haplotype diversity in consanguineous populations and fail to discriminate among male relatives from the same pedigree. Rapidly mutating Y-STRs (RM Y-STRs) have received much attention in the past decade. These 13 RM Y-STRs have high mutation rates (>10−2) and have considerably higher haplotype diversity and discrimination capacity than conventionally used Y-STRs, showing remarkable power when it comes to differentiation in paternal lineages in endogamous populations. Previously, we analyzed two to four generations of 99 pedigrees with 1568 pairs of men covering one to six meioses from all over Pakistan and 216 male relatives from 18 deep-rooted endogamous Sindhi pedigrees covering one to seven meioses. Here, we present 861 pairs of men from 62 endogamous pedigrees covering one to six meioses from the Punjabi population of Punjab, Pakistan. Mutations were frequently observed at DYF399 and DYF403, while no mutation was observed at DYS526a/b. The rate of differentiation ranged from 29.70% (first meiosis) to 80.95% (fifth meiosis), while overall (first to sixth meiosis) differentiation was 59.46%. Combining previously published data with newly generated data, the overall differentiation rate was 38.79% based on 5176 pairs of men related by 1–20 meioses, while Yfiler differentiation was 9.24% based on 3864 pairs. Using father–son pair data from the present and previous studies, we also provide updated RM Y-STR mutation rates. [ABSTRACT FROM AUTHOR]

In this work, tung oil was utilised as a catalyst-free self-healing agent, and an in-situ polymerization process was applied to encapsulate the tung oil core with a poly(urea-formaldehyde) (PUF) shell. The conventional poly(ethylene-alt-maleic-anhydride) (PEMA) polymer was compared to a more naturally abundant gelatin (GEL) emulsifier to compare the microcapsules' barrier, morphological, thermal, and chemical properties, and the crystalline nature of the shell material. GEL emulsifiers produced microcapsules with a higher payload (96.5%), yield (28.9%), and encapsulation efficiency (61.7%) compared to PEMA (90.8%, 28.6% and 52.6%, respectively). Optical and electron microscopy imaging indicated a more uniform morphology for the GEL samples. The thermal decomposition measurements indicated that GEL decomposed to a value 7% lower than that of PEMA, which was suggested to be attributed to the much thinner shell materials that the GEL samples produced. An innovative and novel focused ion beam (FIB) milling method was exerted on the GEL sample, confirming the storage and release of the active tung oil material upon rupturing. The samples with GEL conveyed a higher healing efficiency of 91%, compared to PEMA's 63%, and the GEL samples also conveyed higher levels of corrosion resistance. [ABSTRACT FROM AUTHOR]

Repetitive transcranial magnetic stimulation (rTMS) is effective in the treatment of depression. However, for the subset of patients with bipolar disorder, less data is available and overall strength of evidence is weaker than for its use in unipolar depression. A cohort of 505 patients (of which 46 had a diagnosis of bipolar disorder) with depression who were treated with rTMS were analyzed retrospectively with regards to their response to several weeks of treatment. Hamilton Depression Rating Scale (HDRS) was assessed as main outcome. Unipolar and bipolar patients with depression did not differ significantly in baseline demographic variables or severity of depression. Both groups did not differ significantly in their response to treatment as indicated by absolute and relative changes in the HDRS and response and remission rates. On HDRS subitem-analysis, bipolar patients showed superior amelioration of the symptom "paranoid symptoms" in a statistically significant manner. In conclusion, depressed patients with a diagnosis of bipolar disorder benefit from rTMS in a similar fashion as patients with unipolar depression in a naturalistic setting. rTMS might be more effective in reducing paranoia in bipolar than in unipolar patients. [ABSTRACT FROM AUTHOR]

A numerical simulation study on elastic wave propagation of a phononic composite structure consisting of epoxy and tungsten carbide is presented for low-frequency elastic wave attenuation applications. The calculated dispersion curves of the epoxy/tungsten carbide composite show that the propagation of elastic waves is prohibited inside the periodic structure over a frequency range. To achieve a wide bandgap, the elastic composite structure can be optimized by changing its dimensions and arrangement, including size, number, and rotation angle of square inclusions. The simulation results show that increasing the number of inclusions and the filling fraction of the unit cell significantly broaden the phononic bandgap compared to other geometric tunings. Additionally, a nonmonotonic relationship between the bandwidth and filling fraction of the composite was found, and this relationship results from spacing among inclusions and inclusion sizes causing different effects on Bragg scatterings and localized resonances of elastic waves. Moreover, the calculated transmission spectra of the epoxy/tungsten carbide composite structure verify its low-frequency bandgap behavior. [ABSTRACT FROM AUTHOR]

Despite the availability of some studies related to rainfall characteristics in Sharjah city and the UAE, very few of these studies have investigated any causal link between recent cloud-seeding missions and the increasing rainfall intensities and urban floods being experienced. This study has assessed the impact of cloud-seeding operations that started in 2010 on the IDF curves of Sharjah city, The UAE. Hourly rainfall data spanning between 2010 and 2020 available at three stations, namely Sharjah Airport, Al Dhaid, and Mleiha, and provided by the National Center of Meteorology were used. To allow comparison with the pre-cloudseeding (2010) era, these records were extended back to 1992 using the much longer data available at Dubai Airport with the aid of the Self-organizing map approach. The developed IDF curves showed an apparent increase in rainfall intensities after implementing the cloud-seeding missions. In addition, the estimated mean rainfall intensities for three regions of the city were also much higher for the cloudseeded years compared to the pre-cloudseeding period. The study suggests that, while cloud-seeding provides water security benefits, its impact on urban flooding should also be carefully considered in the context of urban development plans. [ABSTRACT FROM AUTHOR]