1. Transgenerational Immune Priming in the Field:Maternal Environmental Experience Leads to Differential Immune Transfer to Oocytes in the Marine Annelid Hediste diversicolor
- Author
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Aurélie Tasiemski, François Massol, Virginie Cuvillier-Hot, Clémentine Bernier, Céline Boidin-Wichlacz, Nina Hautekeete, Évolution, Écologie et Paléontologie (Evo-Eco-Paleo) - UMR 8198 [Evo-Eco-Paléo (EEP)], Évolution, Écologie et Paléontologie (Evo-Eco-Paleo) - UMR 8198 (Evo-Eco-Paléo (EEP)), Université de Lille-Centre National de la Recherche Scientifique (CNRS), Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 (CIIL), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Centre National de la Recherche Scientifique (CNRS), This research was funded by the Fédération de recherche IREPSE, the Région Hauts-de-France (VERMER project), the EC2CO Program (TRANS-LATE project), and the CPER CLIMIBIO program., Authors are grateful to Anne Duputié for her help with statistical tools, and to Laura Izydorczyk and Timothée Pennel for technical help., Évolution, Écologie et Paléontologie (Evo-Eco-Paleo) - UMR 8198 (Evo-Eco-Paléo), Centre National de la Recherche Scientifique (CNRS)-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Université de Lille-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Pasteur de Lille, and Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)
- Subjects
0106 biological sciences ,0301 basic medicine ,maternal effect ,antimicrobial peptide ,Polychaeta ,pollutants ,hedistin ,TGIP ,immunity ,lysozyme ,MPII ,[SDE.MCG]Environmental Sciences/Global Changes ,Zoology ,Priming (immunology) ,Biology ,010603 evolutionary biology ,01 natural sciences ,[SDV.IMM.II]Life Sciences [q-bio]/Immunology/Innate immunity ,[SDV.BDLR.RS]Life Sciences [q-bio]/Reproductive Biology/Sexual reproduction ,03 medical and health sciences ,Immune system ,Immunity ,biology.animal ,Genetics ,Genetics (clinical) ,Annelid ,Maternal effect ,Vertebrate ,biochemical phenomena, metabolism, and nutrition ,biology.organism_classification ,[SDV.BA.ZI]Life Sciences [q-bio]/Animal biology/Invertebrate Zoology ,030104 developmental biology ,Hediste diversicolor ,[SDV.IMM]Life Sciences [q-bio]/Immunology ,[SDV.TOX.ECO]Life Sciences [q-bio]/Toxicology/Ecotoxicology ,[SDE.BE]Environmental Sciences/Biodiversity and Ecology ,Paternal care ,[SDV.EE.IEO]Life Sciences [q-bio]/Ecology, environment/Symbiosis - Abstract
Transgenerational immune priming (TGIP) is an intriguing form of parental care which leads to the plastic adjustment of the progeny&rsquo, s immunity according to parental immune experience. Such parental effect has been described in several vertebrate and invertebrate taxa. However, very few empirical studies have been conducted from the field, with natural host-parasite systems and real ecological settings, especially in invertebrates. We investigated TGIP in wild populations of the marine annelid Hediste diversicolor. Females laid eggs in a mud tube and thus shared the local microbial threats with the first developmental stages, thus meeting expectations for the evolution of TGIP. We evidenced that a maternal bacterial challenge led to the higher antibacterial defense of the produced oocytes, with higher efficiency in the case of Gram-positive bacterial challenge, pointing out a prevalent role of these bacteria in the evolutionary history of TGIP in this species. Underlying mechanisms might involve the antimicrobial peptide hedistin that was detected in the cytoplasm of oocytes and whose mRNAs were selectively stored in higher quantity in mature oocytes, after a maternal immune challenge. Finally, maternal immune transfer was significantly inhibited in females living in polluted areas, suggesting associated costs and the possible trade-off with female&rsquo, s protection.
- Published
- 2019
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