1. The Interaction of the Endogenous Hydrogen Sulfide and Oxytocin Systems in Fluid Regulation and the Cardiovascular System
- Author
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Christiane Waller, Tamara Merz, Peter Radermacher, Sarah Ecker, Nicole Denoix, Oscar McCook, and Rui Wang
- Subjects
0301 basic medicine ,DOWN-REGULATION ,DDC 540 / Chemistry & allied sciences ,Biological correlates ,Physiology ,Clinical Biochemistry ,hydrogen sulfide ,Endogeny ,Biochemistry ,0302 clinical medicine ,DDC 570 / Life sciences ,INDUCED CARDIOPROTECTION ,Atrial natriuretic peptides ,Psychosomatische Störung ,Hydrogen sulfide ,cardiovascular ,DDC 600 / Technology (Applied sciences) ,Stickstoffoxidsynthase ,Cardiovascular system ,psychosomatic medicine ,ddc:540 ,PORCINE MODEL ,Perspective ,Blood pressure ,H2S DONORS ,medicine.drug ,Psychological trauma ,medicine.medical_specialty ,Cystathionine gamma-lyase ,Blutdruck ,Stress ,Physical trauma ,03 medical and health sciences ,CARDIAC-FUNCTION ,ddc:570 ,medicine ,Molecular Biology ,Fluid regulation ,cystathionine γ-lyase ,Cystathioninlyase (Cystathionin-gamma-lyase) ,business.industry ,lcsh:RM1-950 ,Psychosomatic medicine ,Nitric oxide ,Cell Biology ,Medicine, Psychosomatic ,medicine.disease ,equipment and supplies ,Oxytocin receptor ,oxytocin receptor ,030104 developmental biology ,lcsh:Therapeutics. Pharmacology ,Oxytocin ,fluid regulation ,business ,Schwefelwasserstoff ,Neuroscience ,ddc:600 ,030217 neurology & neurosurgery - Abstract
The purpose of this review is to explore the parallel roles and interaction of hydrogen sulfide (H2S) and oxytocin (OT) in cardiovascular regulation and fluid homeostasis. Their interaction has been recently reported to be relevant during physical and psychological trauma. However, literature reports on H2S in physical trauma and OT in psychological trauma are abundant, whereas available information regarding H2S in psychological trauma and OT in physical trauma is much more limited. This review summarizes recent direct and indirect evidence of the interaction of the two systems and their convergence in downstream nitric oxide-dependent signaling pathways during various types of trauma, in an effort to better understand biological correlates of psychosomatic interdependencies., publishedVersion
- Published
- 2020