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Your search keyword '"Dong-Hoon Kwak"' showing total 2 results
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2 results on '"Dong-Hoon Kwak"'

1. A Novel Method for Estimating Monocular Depth Using Cycle GAN and Segmentation

Author

Dong-hoon Kwak and Seung-Ho Lee

Subjects
Similarity (geometry), Computer science, ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION, adversarial loss, cycle consistency loss, Multi-task learning, multi-task learning, Image processing, monocular depth estimation, 02 engineering and technology, lcsh:Chemical technology, Biochemistry, Article, Analytical Chemistry, 0202 electrical engineering, electronic engineering, information engineering, Segmentation, lcsh:TP1-1185, cycle GAN, Electrical and Electronic Engineering, Instrumentation, Spatial analysis, Monocular, business.industry, segmentation, 020207 software engineering, Pattern recognition, Atomic and Molecular Physics, and Optics, Benchmark (computing), 020201 artificial intelligence & image processing, Augmented reality, Artificial intelligence, business
Abstract

Modern image processing techniques use three-dimensional (3D) images, which contain spatial information such as depth and scale, in addition to visual information. These images are indispensable in virtual reality, augmented reality (AR), and autonomous driving applications. We propose a novel method to estimate monocular depth using a cycle generative adversarial network&nbsp, (GAN) and segmentation. In this paper, we propose a method for estimating depth information by combining segmentation. It uses three processes: segmentation and depth estimation, adversarial loss calculations, and cycle consistency loss calculations. The cycle consistency loss calculation process evaluates the similarity of two images when they are restored to their original forms after being estimated separately from two adversarial losses. To evaluate the objective reliability of the proposed method, we compared our proposed method with other monocular depth estimation (MDE) methods using the NYU Depth Dataset V2. Our results show that the benchmark value for our proposed method is better than other methods. Therefore, we demonstrated that our proposed method is more efficient in determining depth estimation.

Published
2020

2. Growth Suppression of Colorectal Cancer by Plant-Derived Multiple mAb CO17-1A × BR55 via Inhibition of ERK1/2 Phosphorylation.

Author

Dong Hoon Kwak, Ghislain Moussavou, Ju Hyoung Lee, Sung Youn Heo, Kisung Ko, Kyung-A Hwang, Seung-Joo Jekal, and Young-Kug Choo

Subjects
*COLON cancer prevention, *COLON cancer treatment, *MONOCLONAL antibodies, *ANTINEOPLASTIC agents, *TRANSGENIC plants, *PHOSPHORYLATION, *APOPTOSIS
Abstract

We have generated the transgenic Tabaco plants expressing multiple monoclonal antibody (mAb) CO7-1A × BR55 by cross-pollinating with mAb CO17-1A and mAb BR55. We have demonstrated the anti-cancer effect of plant-derived multiple mAb CO17-1A × BR55. We find that co-treatment of colorectal mAbs (anti-epithelial cellular adhesion molecule (EpCAM), plant-derived monoclonal antibody (mAbP) CO17-1A and mAbP CO17-1A × BR55) with RAW264.7 cells significantly inhibited the cell growth in SW620 cancer cells. In particular, multi mAbP CO17-1A × BR55 significantly and efficiently suppressed the growth of SW620 cancer cells compared to another mAbs. Apoptotic death-positive cells were significantly increased in the mAbP CO17-1A × BR55-treated. The mAbP CO17-1A × BR55 treatment significantly decreased the expression of B-Cell lymphoma-2 (BCl-2), but the expression of Bcl-2-associated X protein (Bax), and cleaved caspase-3 were markedly increased. In vivo, the mAbP CO17-1A × BR55 significantly and efficiently inhibited the growth of colon tumors compared to another mAbs. The apoptotic cell death and inhibition of pro-apoptotic proteins expression were highest by treatment with mAbP CO17-1A × BR55. In addition, the mAbP CO17-1A × BR55 significantly inhibited the extracellular signal-regulated kinase 1 and 2 (ERK1/2) phosphorylation in cancer cells and tumors. Therefore, this study results suggest that multiple mAbP CO17-1A × BR55 has a significant effect on apoptosis-mediated anticancer by suppression of ERK1/2 phosphorylation in colon cancer compared to another mAbs. In light of these results, further clinical investigation should be conducted on mAbP CO17-1A × BR55 to determine its possible chemopreventive and/or therapeutic efficacy against human colon cancer. [ABSTRACT FROM AUTHOR]

Published
2014
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