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Relating continuously collected inertial data to the activities or postures performed by the sensor wearer requires pattern recognition or machine-learning-based algorithms, accounting for the temporal and scale variability present in human movements. The objective of this study was to develop a sensor-based framework for the detection and measurement of high-flexion postures frequently adopted in occupational settings. IMU-based joint angle estimates for the ankle, knee, and hip were time and scale normalized prior to being input to a multi-dimensional Dynamic Time Warping (mDTW) distance-based Nearest Neighbour algorithm for the identification of twelve postures. Data from 50 participants were divided to develop and evaluate the mDTW model. Overall accuracies of 82.3% and 55.6% were reached when classifying movements from the testing and validation datasets, respectively, which increased to 86% and 74.6% when adjusting for imbalances between classification groups. The highest misclassification rates occurred between flatfoot squatting, heels-up squatting, and stooping, while the model was incapable of identifying sequences of walking based on a single stride template. The developed mDTW model proved robust in identifying high-flexion postures performed by participants both included and precluded from algorithm development, indicating its strong potential for the quantitative measurement of postural adoption in real-world settings.

Developing machine learning algorithms for time-series data often requires manual annotation of the data. To do so, graphical user interfaces (GUIs) are an important component. Existing Python packages for annotation and analysis of time-series data have been developed without addressing adaptability, usability, and user experience. Therefore, we developed a generic open-source Python package focusing on adaptability, usability, and user experience. The developed package, Machine Learning and Data Analytics (MaD) GUI, enables developers to rapidly create a GUI for their specific use case. Furthermore, MaD GUI enables domain experts without programming knowledge to annotate time-series data and apply algorithms to it. We conducted a small-scale study with participants from three international universities to test the adaptability of MaD GUI by developers and to test the user interface by clinicians as representatives of domain experts. MaD GUI saves up to 75% of time in contrast to using a state-of-the-art package. In line with this, subjective ratings regarding usability and user experience show that MaD GUI is preferred over a state-of-the-art package by developers and clinicians. MaD GUI reduces the effort of developers in creating GUIs for time-series analysis and offers similar usability and user experience for clinicians as a state-of-the-art package.

Indoor localization and human activity recognition are two important sources of information to provide context-based assistance. This information is relevant in ambient assisted living (AAL) scenarios, where older adults usually need supervision and assistance in their daily activities. However, indoor localization and human activity recognition have been mostly considered isolated problems. This work presents and evaluates a framework that takes advantage of the relationship between location and activity to simultaneously perform indoor localization, mapping, and human activity recognition. The proposed framework provides a non-intrusive configuration, which fuses data from an inertial measurement unit (IMU) placed in the person's shoe, with proximity and human activity-related data from Bluetooth low energy beacons (BLE) deployed in the indoor environment. A variant of the simultaneous location and mapping (SLAM) framework was used to fuse the location and human activity recognition (HAR) data. HAR was performed using data streaming algorithms. The framework was evaluated in a pilot study, using data from 22 people, 11 young people, and 11 older adults (people aged 65 years or older). As a result, seven activities of daily living were recognized with an F1 score of 88%, and the in-door location error was 0.98 ± 0.36 m for the young and 1.02 ± 0.24 m for the older adults. Furthermore, there were no significant differences between the groups, indicating that our proposed method works adequately in broad age ranges.

Digital technologies provide the opportunity to analyze gait patterns in patients with Parkinson's Disease using wearable sensors in clinical settings and a home environment. Confirming the technical validity of inertial sensors with a 3D motion capture system is a necessary step for the clinical application of sensor-based gait analysis. Therefore, the objective of this study was to compare gait parameters measured by a mobile sensor-based gait analysis system and a motion capture system as the gold standard. Gait parameters of 37 patients were compared between both systems after performing a standardized 5 × 10 m walking test by reliability analysis using intra-class correlation and Bland-Altman plots. Additionally, gait parameters of an age-matched healthy control group ( n = 14) were compared to the Parkinson cohort. Gait parameters representing bradykinesia and short steps showed excellent reliability (ICC > 0.96). Shuffling gait parameters reached ICC > 0.82. In a stridewise synchronization, no differences were observed for gait speed, stride length, stride time, relative stance and swing time ( p > 0.05). In contrast, heel strike, toe off and toe clearance significantly differed between both systems ( p < 0.01). Both gait analysis systems distinguish Parkinson patients from controls. Our results indicate that wearable sensors generate valid gait parameters compared to the motion capture system and can consequently be used for clinically relevant gait recordings in flexible environments.

Climbing stairs is a fundamental part of daily life, adding additional demands on the postural control system compared to level walking. Although real-world gait analysis studies likely contain stair ambulation sequences, algorithms dedicated to the analysis of such activities are still missing. Therefore, we propose a new gait analysis pipeline for foot-worn inertial sensors, which can segment, parametrize, and classify strides from continuous gait sequences that include level walking, stair ascending, and stair descending. For segmentation, an existing approach based on the hidden Markov model and a feature-based gait event detection were extended, reaching an average segmentation F1 score of 98.5% and gait event timing errors below ±10ms for all conditions. Stride types were classified with an accuracy of 98.2% using spatial features derived from a Kalman filter-based trajectory reconstruction. The evaluation was performed on a dataset of 20 healthy participants walking on three different staircases at different speeds. The entire pipeline was additionally validated end-to-end on an independent dataset of 13 Parkinson's disease patients. The presented work aims to extend real-world gait analysis by including stair ambulation parameters in order to gain new insights into mobility impairments that can be linked to clinically relevant conditions such as a patient's fall risk and disease state or progression.

Indoor location estimation is crucial to provide context-based assistance in home environments. In this study, a method for simultaneous indoor pedestrian localization and house mapping is proposed and evaluated. The method fuses a person's movement data from an Inertial Measurement Unit (IMU) with proximity and activity-related data from Bluetooth Low-Energy (BLE) beacons deployed in the indoor environment. The person's and beacons' localization is performed simultaneously using a combination of particle and Kalman Filters. We evaluated the method using data from eight participants who performed different activities in an indoor environment. As a result, the average participant's localization error was 1.05 ± 0.44 m, and the average beacons' localization error was 0.82 ± 0.24 m. The proposed method is able to construct a map of the indoor environment by localizing the BLE beacons and simultaneously locating the person. The results obtained demonstrate that the proposed method could point to a promising roadmap towards the development of simultaneous localization and home mapping system based only on one IMU and a few BLE beacons. To the best of our knowledge, this is the first method that includes the beacons' data movement as activity-related events in a method for pedestrian Simultaneous Localization and Mapping (SLAM).

The evaluation of trajectory reconstruction of the human body obtained by foot-mounted Inertial Pedestrian Dead-Reckoning (IPDR) methods has usually been carried out in controlled environments, with very few participants and limited to walking. In this study, a pipeline for trajectory reconstruction using a foot-mounted IPDR system is proposed and evaluated in two large datasets containing activities that involve walking, jogging, and running, as well as movements such as side and backward strides, sitting, and standing. First, stride segmentation is addressed using a multi-subsequence Dynamic Time Warping method. Then, detection of Toe-Off and Mid-Stance is performed by using two new algorithms. Finally, stride length and orientation estimation are performed using a Zero Velocity Update algorithm empowered by a complementary Kalman filter. As a result, the Toe-Off detection algorithm reached an F-score between 90% and 100% for activities that do not involve stopping, and between 71% and 78% otherwise. Resulting return position errors were in the range of 0.5% to 8.8% for non-stopping activities and 8.8% to 27.4% otherwise. The proposed pipeline is able to reconstruct indoor trajectories of people performing activities that involve walking, jogging, running, side and backward walking, sitting, and standing.

Mobile gait analysis systems based on inertial sensing on the shoe are applied in a wide range of applications. Especially for medical applications, they can give new insights into motor impairment in, e.g., neurodegenerative disease and help objectify patient assessment. One key component in these systems is the reconstruction of the foot trajectories from inertial data. In literature, various methods for this task have been proposed. However, performance is evaluated on a variety of datasets due to the lack of large, generally accepted benchmark datasets. This hinders a fair comparison of methods. In this work, we implement three orientation estimation and three double integration schemes for use in a foot trajectory estimation pipeline. All methods are drawn from literature and evaluated against a marker-based motion capture reference. We provide a fair comparison on the same dataset consisting of 735 strides from 16 healthy subjects. As a result, the implemented methods are ranked and we identify the most suitable processing pipeline for foot trajectory estimation in the context of mobile gait analysis.

The purpose of this study was to assess the concurrent validity and test-retest reliability of a sensor-based gait analysis system. Eleven healthy subjects and four Parkinson's disease (PD) patients were asked to complete gait tasks whilst wearing two inertial measurement units at their feet. The extracted spatio-temporal parameters of 1166 strides were compared to those extracted from a reference camera-based motion capture system concerning concurrent validity. Test-retest reliability was assessed for five healthy subjects at three different days in a two week period. The two systems were highly correlated for all gait parameters ( r > 0.93 ). The bias for stride time was 0 ± 16 ms and for stride length was 1.4 ± 6.7 cm. No systematic range dependent errors were observed and no significant changes existed between healthy subjects and PD patients. Test-retest reliability was excellent for all parameters (intraclass correlation (ICC) > 0.81) except for gait velocity (ICC > 0.55). The sensor-based system was able to accurately capture spatio-temporal gait parameters as compared to the reference camera-based system for normal and impaired gait. The system's high retest reliability renders the use in recurrent clinical measurements and in long-term applications feasible., Competing Interests: None of the authors declare any conflicts of interest with respect to this study. Simi Reality Motion Systems GmbH rented the camera system but was not involved in the design of the study, the data collection, analyses, or interpretation of data, in the writing of the manuscript, or in the decision to publish the results.