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Insecticide testing facilities that evaluate a variety of vector control products may generate a large number of hazardous wastes from routine operations. These wastes originate from degraded technical grade materials, sprayed substrates with Indoor Residual Spraying (IRS), and redundant stock or working insecticidal solutions. The washing of Long-Lasting Insecticidal Nets (LLINs) during preparation for laboratory and experimental hut trials also contribute to wastewater with insecticide content. Human and environmental exposure to insecticidal waste can occur during transport, categorization, storage, and disposal, resulting in environmental pollution and potential health effects. Various national and international guidelines have been devised for safe disposal and should be strictly followed to avoid adverse effects on humans or environment. To facilitate proper insecticidal waste management, this paper outlines simple but safe practices derived from international and national guidelines that can be adopted by other similar facilities. National and international policies related to chemical management were reviewed and translated into Standard Operating Procedures (SOPs), training pathways, and manuals. National Environmental Management Council (NEMC) assessed the test facility and recommended disposal procedures. NEMC recommendations were followed to construct the soak pits for liquid waste disposal while chemical transporters and incinerators were contracted for solid waste disposal. An environmental expert was contracted for environmental audit and annual monitoring. Studies and activities at the facility were evaluated for their waste generation index. Safety manual and SOPs on risk assessment, waste management and disposal, handling hazardous materials, health and safety procedures, and chemical usage were written. At KCMUCo-PAMVERC, an annual average of 0.02 and 24.9 cubic meters of liquid waste, which mainly includes a mixture of water, insecticides, and solvents, were generated from laboratory experiments (phase I) and semi-field LLIN experiments (phase II), respectively, while the IRS semi-field experiments generated an annual average of 88 L of liquid waste and 6.3 tons of solid waste. An annual average of 0.18 cubic meters of liquid waste results from other sources, including expired laboratory reagents. Well-translated national and international policies/regulations may be adopted by insecticide test facilities for proper and effective waste disposal.