1. Making of Viral Replication Organelles by Remodeling Interior Membranes.
- Author
-
Sasvari, Zsuzsanna and Nagy, Peter D.
- Subjects
- *
RNA viruses , *VIRAL replication , *CELL membranes , *POLIOVIRUS , *CORONAVIRUSES , *VIRAL proteins - Abstract
Positive-stranded RNA (+RNA) viruses exploit host cell machinery by subverting host proteins and membranes and altering cellular pathways during infection. To achieve robust replication, some +RNA viruses, such as poliovirus (PV), build special intracellular compartments, called viral replication organelles. A recent work from the Altan-Bonnett laboratory [1] gave new insights into the formation of poliovirus replication organelles, which are unique subcellular structures containing many individual replication complexes as a result of dynamic cellular membrane remodeling. [ABSTRACT FROM AUTHOR]
- Published
- 2010
- Full Text
- View/download PDF