1. Low-Cost and Rapid Fabrication of Metallic Nanostructures for Sensitive Biosensors Using Hot-Embossing and Dielectric-Heating Nanoimprint Methods
- Author
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Pei-Kuen Wei, Tsung-Yeh Wu, Kuang-Li Lee, Sen-Yeu Yang, and Hsuan-Yeh Hsu
- Subjects
Plastic welding ,Fabrication ,Nanostructure ,Materials science ,metallic nanostructures ,hot-embossing ,radio-frequency heating ,Nanotechnology ,02 engineering and technology ,Biosensing Techniques ,010402 general chemistry ,lcsh:Chemical technology ,01 natural sciences ,Biochemistry ,Article ,Analytical Chemistry ,Heating ,Dielectric heating ,Figure of merit ,lcsh:TP1-1185 ,Electrical and Electronic Engineering ,Instrumentation ,template-stripping ,Fano resonance ,Surface Plasmon Resonance ,021001 nanoscience & nanotechnology ,biosensors ,Atomic and Molecular Physics, and Optics ,0104 chemical sciences ,Nanostructures ,Nanolithography ,Gold ,0210 nano-technology ,Biosensor - Abstract
We propose two approaches—hot-embossing and dielectric-heating nanoimprinting methods—for low-cost and rapid fabrication of periodic nanostructures. Each nanofabrication process for the imprinted plastic nanostructures is completed within several seconds without the use of release agents and epoxy. Low-cost, large-area, and highly sensitive aluminum nanostructures on A4 size plastic films are fabricated by evaporating aluminum film on hot-embossing nanostructures. The narrowest bandwidth of the Fano resonance is only 2.7 nm in the visible light region. The periodic aluminum nanostructure achieves a figure of merit of 150, and an intensity sensitivity of 29,345%/RIU (refractive index unit). The rapid fabrication is also achieved by using radio-frequency (RF) sensitive plastic films and a commercial RF welding machine. The dielectric-heating, using RF power, takes advantage of the rapid heating/cooling process and lower electric power consumption. The fabricated capped aluminum nanoslit array has a 5 nm Fano linewidth and 490.46 nm/RIU wavelength sensitivity. The biosensing capabilities of the metallic nanostructures are further verified by measuring antigen–antibody interactions using bovine serum albumin (BSA) and anti-BSA. These rapid and high-throughput fabrication methods can benefit low-cost, highly sensitive biosensors and other sensing applications.
- Published
- 2017