1. Growing Teratoma Syndrome in the Setting of Sarcoidosis: A Case Report and Literature Review.
- Author
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Shahnam, Adel, Sayer, Robyn, Herbst, Unine, Sharma, Raghwa, Yoon, Won-hee, Dinihan, Tim, and Gao, Bo
- Subjects
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TERATOMA , *SARCOIDOSIS , *ADJUVANT chemotherapy , *COMPUTED tomography , *POSITRON emission tomography - Abstract
Growing teratoma syndrome (GTS) is rare and can mimic disease recurrence in patients with a history of immature teratoma. Benign hypermetabolic lymphadenopathy found on staging and surveillance computed tomography (CT) and positron emission tomography (PET) may lead to the presumption of metastatic malignancy. We report a case of a 38 year old with mixed mature and immature teratomas who developed new peritoneal masses after adjuvant chemotherapy despite a normalization of tumor markers. In addition to low FDG uptake observed in these peritoneal masses, a PET scan showed hypermetabolic lymphadenopathy and pulmonary and spleen lesions suggesting widespread metastases. Subsequent surgical resection confirmed a mixed pathology with GTS and sarcoidosis. We reviewed the current literature evidence of GTS and sarcoidosis as a benign cause of lymphadenopathy in cancer patients. We emphasize the importance of a tissue diagnosis before instituting therapy for presumed cancer recurrence to avoid potentially fatal diagnostic traps and management errors. A multiple disciplinary team approach is imperative in managing patients with suspected recurrent immature teratomas. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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