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The term Machinekin denotes a sub-group of a larger Internet subculture known as Otherkin: while recognizing they have a human body and mind, these people nevertheless identify as being other-than-human. Machinekin therefore identify as a machine of some sort. In attempting to study this subculture, qualitative psychological research methods are used, combined with digital ethnography. Postmodern theories of identity formation, such as narrative identity, and especially McAdams's seven features of the life-story, are implemented in order to interpret how Neve, a Machinekin, came to understand his non-human identity, as well as the role religion has played in his identity configuration. Additionally, the function of religion as it applies to finding meaning in conflicting circumstances is also considered. Neve's experiences can be seen as an example of how religion and identity are interrelated, with the story showing what key events led Neve to look to religion for answers to difficult questions that arose in his early years. The interpretation of these events eventually led to an understanding of Neve's lived experiences, and to a sense of purpose for his life. It also demonstrates how Machinekin challenge attitudes surrounding identity and the boundaries of what constitutes a "person". [ABSTRACT FROM AUTHOR]

Background: Human papillomaviruses (HPVs) have been linked to a variety of human cancers. As the landscape of HPV-related neoplasia continues to expand, uncommon and rare HPV genotypes have also started to emerge. Host-virus interplay is recognized as a key driver in HPV carcinogenesis, with host immune status, virus genetic variants and coinfection highly influencing the dynamics of malignant transformation. Immunosuppression and tissue tropism are also known to influence HPV pathogenesis. Methods: Herein, we present a case of a patient who, in the setting of HIV positivity, developed anal squamous cell carcinoma associated with HPV69 and later developed squamous cell carcinoma in the lungs, clinically presumed to be metastatic disease, associated with HPV73. Consensus PCR screening for HPV was performed by real-time PCR amplification of the L1 gene region, amplification of the E6 regions with High-Resolution Melting Curve Analysis followed by Sanger sequencing confirmation and phylogenetic analysis. Results: Sanger sequencing of the consensus PCR amplification product determined that the anal tissue sample was positive for HPV 69, and the lung tissue sample was positive for HPV 73. Conclusions: This case underscores the importance of recognizing the emerging role of these rare "possibly carcinogenic" HPV types in human carcinogenesis. [ABSTRACT FROM AUTHOR]