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Iris typhifolia Kitag is a perennial herbaceous species with high ornamental and applied value. Elucidating the mechanism of saline–alkali tolerance in Iris is crucial for their promotion in saline–alkali areas. Saline–alkali stress is one of the factors that affects plant growth, which has become a significant global issue. In this study, we measured the physiological and biochemical indexes of I. typhifolia, through germination and potting trials, to evaluate the resistance of I. typhifolia to different levels of artificial saline–alkali stress (0, 50, 100, 150, and 200 mmol·L−1). The results showed that artificial saline–alkali stress negatively impacted germination parameters, cell membrane integrity, and photosynthetic parameters. Different trends in osmoregulatory substances and endogenous hormones were observed. It was shown that I. typhifolia had a potential adaptability to the saline–alkali environment by enhancing its internal defense mechanism. Based on regression analyses, the germination threshold of I. typhifolia was calculated to be 87.15 mmol·L−1, which provided a theoretical basis for the application in soil saline–alkalization areas. [ABSTRACT FROM AUTHOR]

Simple Summary: Ribosomes are macromolecular complexes responsible for mRNA translation. When ribosome biogenesis is hyperactive or aberrant or ribosomal factors are mutated, ribosomopathies may occur, elevating cancer risks. This review aims to discuss recent research regarding the complex mechanism responsible for regulating ribosome biogenesis and delineate how the deregulation of this process is connected to cancer pathogenesis. Providing our perspective on how these observations provide opportunities for designing new targeted cancer treatments. In doing so, we hope to draw attention to persisting gaps in the literature and candidate targets involved in ribosomal biogenesis for cancer therapies to facilitate further research in this field. Ribosomes are macromolecular ribonucleoprotein complexes assembled from RNA and proteins. Functional ribosomes arise from the nucleolus, require ribosomal RNA processing and the coordinated assembly of ribosomal proteins (RPs), and are frequently hyperactivated to support the requirement for protein synthesis during the self-biosynthetic and metabolic activities of cancer cells. Studies have provided relevant information on targeted anticancer molecules involved in ribosome biogenesis (RiBi), as increased RiBi is characteristic of many types of cancer. The association between unlimited cell proliferation and alterations in specific steps of RiBi has been highlighted as a possible critical driver of tumorigenesis and metastasis. Thus, alterations in numerous regulators and actors involved in RiBi, particularly in cancer, significantly affect the rate and quality of protein synthesis and, ultimately, the transcriptome to generate the associated proteome. Alterations in RiBi in cancer cells activate nucleolar stress response-related pathways that play important roles in cancer-targeted interventions and immunotherapies. In this review, we focus on the association between alterations in RiBi and cancer. Emphasis is placed on RiBi deregulation and its secondary consequences, including changes in protein synthesis, loss of RPs, adaptive transcription and translation, nucleolar stress regulation, metabolic changes, and the impaired ribosome biogenesis checkpoint. [ABSTRACT FROM AUTHOR]

The contamination of urban rivers substantially threatens urban ecology, public health, and general progress. Addressing this matter is complex and challenging, particularly in tidal rivers. After investigating the climate conditions, population, and distribution of rivers and pollution in Sanya, China, a hydraulic and water quality model was built for Sanya utilizing InfoWorks ICM, and a comprehensive remediation approach was proposed. The implementation of this scheme led to a substantial decrease in point and non-point sources of pollution. In particular, COD, NH3-N, and TP were reduced by 87.00%, 84.01%, and 74.24%, respectively, from point source pollution. Point source pollution was well-managed north of the bridge, with a reduction rate close to 40% for non-point source pollution. This research confirmed that pollutants are only temporarily retained in the river at high tide and are discharged as the tide recedes, thus having a limited impact on long-term pollution discharge. This research provides valuable references for applying water environment models and the comprehensive treatment of tidal river pollution. The final plan scheme is to significantly improve the water quality of Sanya's rivers by effectively controlling the discharge of pollutants while achieving considerable cost savings of approximately CNY 1.7 billion. [ABSTRACT FROM AUTHOR]

To substitute fossil resources, it is necessary to investigate the conversion of biomass into 1,2-propanediol (1,2-PDO) as a high-value-added chemical. The Pt/deAl-Beta@Mg(OH)2 catalytic system is designed to obtain a higher 1,2-PDO production yield. The optimal yield of 1,2-PDO is 34.1%. The unique shell-core structure of the catalyst demonstrates stability, with a catalytic yield of over 30% after three times of use. The primary process path from glucose to 1,2-PDO, glucose-hexitol-1,2-PDO, is speculated by the experiments of intermediate product selectivity. The alkaline catalytic mechanism of the reaction process is elucidated by studying catalyst characterization and analyzing different time courses of products. The introduction of Mg(OH)2 improves the target yield by promoting the isomerization from glucose to fructose and retro-aldol condensation (RAC) conversion, with pseudo-yield increases of 76.1% and 42.1%, respectively. By studying the processes of producing lactic acid and 1,2-PDO from glucose, the glucose hydrogenolysis flow chart is improved, which is of great significance for accurately controlling 1,2-PDO production in industrial applications. The metal, acid, and alkali synergistic catalytic system constructed in this paper can provide a theoretical basis and route reference for applying biomass conversion technology in practice. [ABSTRACT FROM AUTHOR]