1. Investigation of Flexible Arrayed Lactate Biosensor Based on Copper Doped Zinc Oxide Films Modified by Iron–Platinum Nanoparticles
- Author
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Yu-Hao Huang, Tsu-Yang Lai, Chih-Sung Ho, Tzu-Yu Su, Jung-Chuan Chou, Yu-Hsun Nien, Po-Yu Kuo, Zhi-Xuan Kang, Chih-Hsien Lai, Yung-Yu Chen, and Zhe-Xin Dong
- Subjects
Materials science ,Polymers and Plastics ,Scanning electron microscope ,lactate detection ,Organic chemistry ,chemistry.chemical_element ,Nanoparticle ,electrochemical sensor ,02 engineering and technology ,Zinc ,Electrochemistry ,01 natural sciences ,Article ,QD241-441 ,non-enzymatic biosensor ,Fourier transform infrared spectroscopy ,iron–platinum nanoparticles (FePt NPs) ,copper doped zinc oxide (CZO) sensing film ,010401 analytical chemistry ,General Chemistry ,021001 nanoscience & nanotechnology ,0104 chemical sciences ,Dielectric spectroscopy ,Electrochemical gas sensor ,chemistry ,0210 nano-technology ,Biosensor ,Nuclear chemistry - Abstract
Potentiometric biosensors based on flexible arrayed silver paste electrode and copper-doped zinc oxide sensing film modified by iron-platinum nanoparticles (FePt NPs) are designed and manufactured to detect lactate in human. The sensing film is made of copper-doped zinc oxide (CZO) by a radio frequency (RF) sputtering system, and then modified by iron-platinum nanoparticles (FePt NPs). The surface morphology of copper-doped zinc oxide (CZO) is analyzed by scanning electron microscope (SEM). FePt NPs are analyzed by X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR). The average sensitivity, response time, and interference effect of the lactate biosensors are analyzed by voltage-time (V-T) measurement system. The electrochemical impedance is analyzed by electrochemical impedance spectroscopy (EIS). The average sensitivity and linearity over the concentration range 0.2–5 mM are 25.32 mV/mM and 0.977 mV/mM, respectively. The response time of the lactate biosensor is 16 s, with excellent selectivity.
- Published
- 2021