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Your search keyword '"Alsahafi, Rashed"' showing total 9 results
Start Over Author "Alsahafi, Rashed" Publisher mdpi ag
9 results on '"Alsahafi, Rashed"'

1. Novel Remineralizing and Antibiofilm Low-Shrinkage-Stress Nanocomposites to Inhibit Salivary Biofilms and Protect Tooth Structures

Author

Alhussein, Abdullah, primary, Alsahafi, Rashed, additional, Alfaifi, Areej, additional, Alenizy, Mohammad, additional, Ba-Armah, Ibrahim, additional, Schneider, Abraham, additional, Jabra-Rizk, Mary-Ann, additional, Masri, Radi, additional, Garcia Fay, Guadalupe, additional, Oates, Thomas W., additional, Sun, Jirun, additional, Weir, Michael D., additional, and Xu, Hockin H. K., additional

Published
2023
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2. Novel Bioactive Nanocomposites Containing Calcium Fluoride and Calcium Phosphate with Antibacterial and Low-Shrinkage-Stress Capabilities to Inhibit Dental Caries

Author

Alhussein, Abdullah, primary, Alsahafi, Rashed, additional, Balhaddad, Abdulrahman A., additional, Mokeem, Lamia, additional, Schneider, Abraham, additional, Jabra-Rizk, Mary-Ann, additional, Masri, Radi, additional, Hack, Gary D., additional, Oates, Thomas W., additional, Sun, Jirun, additional, Weir, Michael D., additional, and Xu, Hockin H. K., additional

Published
2023
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9. Novel CaF 2 Nanocomposites with Antibacterial Function and Fluoride and Calcium Ion Release to Inhibit Oral Biofilm and Protect Teeth.

Author

Mitwalli H, Balhaddad AA, AlSahafi R, Oates TW, Melo MAS, Xu HHK, and Weir MD

Abstract

(1) Background: The objective of this study was to develop a novel dental nanocomposite containing dimethylaminohexadecyl methacrylate (DMAHDM), 2-methacryloyloxyethyl phosphorylcholine (MPC), and nanoparticles of calcium fluoride (nCaF 2 ) for preventing recurrent caries via antibacterial, protein repellent and fluoride releasing capabilities. (2) Methods: Composites were made by adding 3% MPC, 3% DMAHDM and 15% nCaF 2 into bisphenol A glycidyl dimethacrylate (Bis-GMA) and triethylene glycol dimethacrylate (TEGDMA) (denoted BT). Calcium and fluoride ion releases were evaluated. Biofilms of human saliva were assessed. (3) Results: nCaF 2 +DMAHDM+MPC composite had the lowest biofilm colony forming units (CFU) and the greatest ion release; however, its mechanical properties were lower than commercial control composite ( p < 0.05). nCaF 2 +DMAHDM composite had similarly potent biofilm reduction, with mechanical properties matching commercial control composite ( p > 0.05). Fluoride and calcium ion releases from nCaF 2 +DMAHDM were much more than commercial composite. Biofilm CFU on composite was reduced by 4 logs ( n = 9, p < 0.05). Biofilm metabolic activity and lactic acid were also substantially reduced by nCaF 2 +DMAHDM, compared to commercial control composite ( p < 0.05). (4) Conclusions: The novel nanocomposite nCaF 2 +DMAHDM achieved strong antibacterial and ion release capabilities, without compromising the mechanical properties. This bioactive nanocomposite is promising to reduce biofilm acid production, inhibit recurrent caries, and increase restoration longevity.

Published
2020
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