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Your search keyword '"Brizita Djordjevic"' showing total 2 results
Start Over Author "Brizita Djordjevic" Publisher mdpi ag
2 results on '"Brizita Djordjevic"'

1. Epigenetic Aspects of a New Probiotic Concept—A Pilot Study

Author

Nina Okuka, Verena Schuh, Ulrike Krammer, Snezana Polovina, Mirjana Sumarac-Dumanovic, Neda Milinkovic, Ksenija Velickovic, Brizita Djordjevic, Alexander Haslberger, and Nevena Dj. Ivanovic

Subjects
obesity, probiotics, epigenetic markers, mRNA, miRNAs, SIRT1, Science
Abstract

Several studies report the important role of an altered gut microbiota in the development of obesity, highlighting the potential use of probiotics in the treatment of obesity. The aim of this study is to investigate the effect of a novel probiotic approach on the expression of specific miRNAs and mRNAs associated with obesity in combination with the hypocholesterolemic octacosanol. Twenty overweight/obese women participated in a randomized, placebo-controlled, double-blind study and were randomly divided into two groups: the intervention group (daily one capsule containing Lactobacillus plantarum 299v (DSM9843), Saccharomyces cerevisiae var. boulardii, and 40 mg octacosanol; N = 12) and the placebo group (N = 8). Changes in lipid parameters and expression of miRNAs and mRNAs were assessed before (T0) and after the 12-week intervention (T1). After the intervention, the expression of miR-155-5p (9.38 ± 0.85 vs. 8.38 ± 1.06, p = 0.05) and miR-24-3p (3.42 ± 0.38 vs. 2.71 ± 0.97, p = 0.031) showed significant decreases in the intervention group when compared to the control group. At T1, the expression of miR-155-5p (8.69 ± 1.31 vs. 9.3 ± 0.85, p = 0.04), miR-125b-5p (5.41 ± 1.18 vs. 5.99 ± 1.36, p = 0.049), and TNF-α (10.24 ± 1.66 vs. 11.36 ± 1.12, p = 0.009) were significantly decreased in the intervention group. No changes in lipids and anthropometric parameters were observed. The novel probiotic approach had a positive effect on regulating the expression of certain miRNAs and mRNAs important for regulating inflammation and adipogenesis, which are essential for obesity onset and control.

Published
2023
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2. A Cross-Sectional Survey of Salty Snack Consumption among Serbian Urban-Living Students and Their Contribution to Salt Intake

Author

Dušanka Krajnović, Jelena Kotur-Stevuljevic, Sladjana Sobajic, Brizita Djordjevic, Heiner Boeing, and Jasmina B. Timić

Subjects
Male, salty snack products, 0301 basic medicine, Younger age, Urban Population, Cross-sectional study, 0302 clinical medicine, Surveys and Questionnaires, 030212 general & internal medicine, Meal, Schools, Nutrition and Dietetics, students, Snacking, 4. Education, digestive, oral, and skin physiology, food and beverages, salt intake, Female, Psychology, lcsh:Nutrition. Foods and food supply, Serbia, Adult, Adolescent, Universities, Consumption, education, lcsh:TX341-641, Diet Surveys, Article, Food Preferences, Young Adult, 03 medical and health sciences, Environmental health, Humans, consumption, Sodium Chloride, Dietary, Salt intake, Students, Salty snack products, Urban living, Consumption (economics), 030109 nutrition & dietetics, Home environment, Feeding Behavior, Cross-Sectional Studies, Snacks, human activities, Food Science
Abstract

This study investigated the behavior of urban-living students related to the salty snacks consumption, and their contribution to salt daily intake. A cross-sectional survey on 1313 urban-living students (16&ndash, 25 years, 61.4% university students and 38.6% high school students) used a pre-verified questionnaire created specifically for the study. The logistic regression analysis was performed to investigate the factors influencing snack consumption. The results of salt content and the snack consumption frequency were used to evaluate snack contribution to salt intake. All subjects consumed salty snacks, on average several times per week, more often at home and slightly more during periods of intensive studying, with 42% of the participants reporting to consume two or more packages per snacking occasion. Most of the participants consumed such products between main meals, but 10% of them took snacks immediately after the main meal. More high-school students than university students were in the &ldquo, high snack group&rdquo, (p &lt, 0.05). The most frequently consumed salty snacks were those with the highest content of salt. Salt intake from snack products for a majority of participants ranged between 0.4 and 1 g/day. The research revealed younger age, home environment and significant contribution to salt intake as critical points in salty snack consumption among urban-living students important for the better understanding of their dietary habits.

Published
2020
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