Search

Your search keyword '"Chang-hsien Tsai"' showing total 2 results
Start Over Author "Chang-hsien Tsai" Publisher mdpi ag
2 results on '"Chang-hsien Tsai"'

1. Synthesis of 2-Alkenyl-2H-indazoles from 2-(2-Carbonylmethyl)-2H-indazoles

Author

Mei-Huey Lin, Kung-Yu Liang, Chang-Hsien Tsai, Yu-Chun Chen, Hung-Chang Hsiao, Yi-Syuan Li, Chung-Hao Chen, and Hau-Chun Wu

Subjects
indazoles, coumarin, regioselective alkylation, styrene, fluorescence, Organic chemistry, QD241-441
Abstract

A procedure has been developed for synthesis of 2-alkenyl-2H-indazoles starting from 2-(2-carbonylmethyl)-2H-indazoles, which are prepared by gallium/aluminium- and aluminium-mediated, direct, regioselective alkylation of indazoles with α-bromocarbonyl compounds. The structure of 3-(2H-indazol-2-yl)-2H-chromen-2-one was proven by X-ray crystallography. The styrene- and coumarin-2H-indazoles produced by using the new method were found to have interesting fluorescence properties.

Published
2016
Full Text
View/download PDF

2. Synthesis of 2-Alkenyl-2H-indazoles from 2-(2-Carbonylmethyl)-2H-indazoles

Author

Chang Hsien Tsai, Mei‐Huey Lin, Kung Yu Liang, Hau Chun Wu, Yi Syuan Li, Yu-Chun Chen, Hung Chang Hsiao, and Chung-Hao Chen

Subjects
Alkylation, Pharmaceutical Science, chemistry.chemical_element, Crystallography, X-Ray, 010402 general chemistry, 01 natural sciences, coumarin, Article, Catalysis, Analytical Chemistry, Styrene, lcsh:QD241-441, chemistry.chemical_compound, lcsh:Organic chemistry, Drug Discovery, Molecule, Organic chemistry, Physical and Theoretical Chemistry, Gallium, indazoles, regioselective alkylation, Molecular Structure, 010405 organic chemistry, Organic Chemistry, styrene, fluorescence, Regioselectivity, Coumarin, 0104 chemical sciences, chemistry, Chemistry (miscellaneous), Molecular Medicine
Abstract

A procedure has been developed for synthesis of 2-alkenyl-2H-indazoles starting from 2-(2-carbonylmethyl)-2H-indazoles, which are prepared by gallium/aluminium- and aluminium-mediated, direct, regioselective alkylation of indazoles with α-bromocarbonyl compounds. The structure of 3-(2H-indazol-2-yl)-2H-chromen-2-one was proven by X-ray crystallography. The styrene- and coumarin-2H-indazoles produced by using the new method were found to have interesting fluorescence properties.

Published
2016

Catalog

Books, media, physical & digital resources
See catalog results