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Your search keyword '"Moreira, Vanessa"' showing total 14 results
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14 results on '"Moreira, Vanessa"'

1. Clinical and Genetic Aspects of Juvenile Amyotrophic Lateral Sclerosis: A Promising Era Emerges

Author

Souza, Paulo Victor Sgobbi de, primary, Serrano, Paulo de Lima, additional, Farias, Igor Braga, additional, Machado, Roberta Ismael Lacerda, additional, Badia, Bruno de Mattos Lombardi, additional, Oliveira, Hélvia Bertoldo de, additional, Barbosa, Alana Strucker, additional, Pereira, Camila Alves, additional, Moreira, Vanessa de Freitas, additional, Chieia, Marco Antônio Troccoli, additional, Barbosa, Adriel Rêgo, additional, Braga, Vinícius Lopes, additional, Pinto, Wladimir Bocca Vieira de Rezende, additional, and Oliveira, Acary Souza Bulle, additional

Published
2024
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2. PNPT1 Spectrum Disorders: An Underrecognized and Complex Group of Neurometabolic Disorders

Author

Sgobbi, Paulo, primary, Farias, Igor Braga, additional, Serrano, Paulo de Lima, additional, Badia, Bruno de Mattos Lombardi, additional, Oliveira, Hélvia Bertoldo de, additional, Barbosa, Alana Strucker, additional, Pereira, Camila Alves, additional, Moreira, Vanessa de Freitas, additional, Chieia, Marco Antônio Troccoli, additional, Barbosa, Adriel Rêgo, additional, Fraiman, Pedro Henrique Almeida, additional, Braga, Vinícius Lopes, additional, Machado, Roberta Ismael Lacerda, additional, Calegaretti, Sophia Luiz, additional, Fernandes, Isabela Danziato, additional, Ribeiro, Roberta Correa, additional, Orsini Neves, Marco Antonio, additional, Pinto, Wladimir Bocca Vieira de Rezende, additional, and Oliveira, Acary Souza Bulle, additional

Published
2024
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3. Hippocampal Endoplasmic Reticulum Stress Hastens Motor and Cognitive Decline in Adult Male Rats Sustainedly Exposed to High-Sucrose Diet

Author

Pinto, Bruno Araújo Serra, primary, Melo, Thamys Marinho, additional, Flister, Karla Frida Torres, additional, França, Lucas Martins, additional, Moreira, Vanessa Ribeiro, additional, Kajihara, Daniela, additional, Mendes, Nelmar Oliveira, additional, Pereira, Silma Regina, additional, Laurindo, Francisco Rafael Martins, additional, and Paes, Antonio Marcus Andrade, additional

Published
2022
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5. Effects of Formyl Peptide Receptor Agonists Ac9-12 and WKYMV in In Vivo and In Vitro Acute Inflammatory Experimental Models

Author

Lice, Izabella, primary, Sanches, José Marcos, additional, Correia-Silva, Rebeca D., additional, Corrêa, Mab P., additional, Icimoto, Marcelo Y., additional, Silva, Alex A. R., additional, Sánchez-Vinces, Salvador, additional, Porcari, Andreia M., additional, Moreira, Vanessa, additional, and Gil, Cristiane D., additional

Published
2022
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7. OTX2 Homeoprotein Functions in Adult Choroid Plexus

Author

Planques, Anabelle, primary, Oliveira Moreira, Vanessa, additional, Benacom, David, additional, Bernard, Clémence, additional, Jourdren, Laurent, additional, Blugeon, Corinne, additional, Dingli, Florent, additional, Masson, Vanessa, additional, Loew, Damarys, additional, Prochiantz, Alain, additional, and Di Nardo, Ariel A., additional

Published
2021
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9. Role of Annexin A1 in NLRP3 Inflammasome Activation in Murine Neutrophils

Author

Sanches, José Marcos, primary, Correia-Silva, Rebeca D., additional, Duarte, Gustavo H. B., additional, Fernandes, Anna Maria A. P., additional, Sánchez-Vinces, Salvador, additional, Carvalho, Patrícia O., additional, Oliani, Sonia M., additional, Bortoluci, Karina R., additional, Moreira, Vanessa, additional, and Gil, Cristiane D., additional

Published
2021
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12. Connexin 43 Controls the Astrocyte Immunoregulatory Phenotype

Author

Boulay, Anne-Cécile, Gilbert, Alice, Oliveira Moreira, Vanessa, Blugeon, Corinne, Perrin, Sandrine, Pouch, Juliette, Le Crom, Stéphane, Ducos, Bertrand, Cohen-Salmon, Martine, Variabilité de réponse aux Psychotropes (VariaPsy - U1144), Université Paris Diderot - Paris 7 (UPD7)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre interdisciplinaire de recherche en biologie (CIRB), Labex MemoLife, École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Collège de France (CdF (institution))-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Plateforme Génomique de l'IBENS, Institut de biologie de l'ENS Paris (IBENS), Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Département de Biologie - ENS Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Département de Biologie - ENS Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Analyse des Données à Haut Débit en Génomique (ADHDG), Evolution Paris Seine, Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Centre National de la Recherche Scientifique (CNRS)-Université des Antilles et de la Guyane (UAG)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Centre National de la Recherche Scientifique (CNRS)-Université des Antilles et de la Guyane (UAG)-Université Pierre et Marie Curie - Paris 6 (UPMC), Laboratoire de Physique Statistique de l'ENS (LPS), Fédération de recherche du Département de physique de l'Ecole Normale Supérieure - ENS Paris (FRDPENS), Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Descartes - Paris 5 (UPD5), Institut de biologie de l'ENS Paris (UMR 8197/1024) (IBENS), Département de Biologie - ENS Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Département de Biologie - ENS Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Université des Antilles et de la Guyane (UAG)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Université Nice Sophia Antipolis (... - 2019) (UNS), and COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Centre National de la Recherche Scientifique (CNRS)

Subjects
astrocyte, inflammation, [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], sense organs, ribosomal-bound transcriptome, [SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], immunity, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Article, connexin 43, lcsh:RC321-571
Abstract

International audience; Astrocytes are the most abundant glial cells of the central nervous system and have recently been recognized as crucial in the regulation of brain immunity. In most neuropathological conditions, astrocytes are prone to a radical phenotypical change called reactivity, which plays a key role in astrocyte contribution to neuroinflammation. However, how astrocytes regulate brain immunity in healthy conditions is an understudied question. One of the astroglial molecule involved in these regulations might be Connexin 43 (Cx43), a gap junction protein highly enriched in astrocyte perivascular endfeet-terminated processes forming the glia limitans. Indeed, Cx43 deletion in astrocytes (Cx43KO) promotes a continuous immune recruitment and an autoimmune response against an astrocyte protein, without inducing any brain lesion. To investigate the molecular basis of this unique immune response, we characterized the polysomal transcriptome of hippocampal astrocytes deleted for Cx43. Our results demonstrate that, in the absence of Cx43, astrocytes adopt an atypical reactive status with no change in most canonical astrogliosis markers, but with an upregulation of molecules promoting immune recruitment, complement activation as well as anti-inflammatory processes. Intriguingly, while several of these upregulated transcriptional events suggested an activation of the γ-interferon pathway, no increase in this cytokine or activation of related signaling pathways were found in Cx43KO. Finally, deletion of astroglial Cx43 was associated with the upregulation of several angiogenic factors, consistent with an increase in microvascular density in Cx43KO brains. Collectively, these results strongly suggest that Cx43 controls immunoregulatory and angiogenic properties of astrocytes.

Published
2018

13. Pharmacological Evaluation and Preliminary Pharmacokinetics Studies of a New Diclofenac Prodrug without Gastric Ulceration Effect

Author

Santos, Jean, primary, Moreira, Vanessa, additional, Campos, Michel, additional, Chelucci, Rafael, additional, Barbieri, Karina, additional, Souto, Pollyana, additional, Matsubara, Márcio, additional, Teixeira, Catarina, additional, Bosquesi, Priscila, additional, Peccinini, Rosângela, additional, and Chin, Chung, additional

Published
2012
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14. The Complex Role Played by the Default Mode Network during Sexual Stimulation: A Cluster-Based fMRI Meta-Analysis.

Author

Pinto J, Comprido C, Moreira V, Maccarone MT, Cogoni C, Faustino R, Pignatelli D, and Cera N

Abstract

The default mode network (DMN) is a complex network that plays a significant and active role during naturalistic stimulation. Previous studies that have used naturalistic stimuli, such as real-life stories or silent or sonorous films, have found that the information processing involved a complex hierarchical set of brain regions, including the DMN nodes. The DMN is not involved in low-level features and is only associated with high-level content-related incoming information. The human sexual experience involves a complex set of processes related to both external context and inner processes. Since the DMN plays an active role in the integration of naturalistic stimuli and aesthetic perception with beliefs, thoughts, and episodic autobiographical memories, we aimed at quantifying the involvement of the nodes of the DMN during visual sexual stimulation. After a systematic search in the principal electronic databases, we selected 83 fMRI studies, and an ALE meta-analysis was calculated. We performed conjunction analyses to assess differences in the DMN related to stimulus modalities, sex differences, and sexual orientation. The results show that sexual stimulation alters the topography of the DMN and highlights the DMN's active role in the integration of sexual stimuli with sexual schemas and beliefs.

Published
2024
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