1. Long-Term Follow-Up Outcomes after Percutaneous US/CT-Guided Radiofrequency Ablation for cT1a-b Renal Masses: Experience from Single High-Volume Referral Center
- Author
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Giovanni Mauri, Daniele Maiettini, Francesco A. Mistretta, Guido Bonomo, N. Piacentini, Paolo Della Vigna, Gianluca Maria Varano, Stefano Luzzago, Matteo Ferro, Ottavio De Cobelli, Nicola Camisassi, Franco Orsi, Gennaro Musi, and A. Conti
- Subjects
Cancer Research ,medicine.medical_specialty ,Percutaneous ,Radiofrequency ablation ,medicine.medical_treatment ,renal cancer ,Computed tomography ,survival ,lcsh:RC254-282 ,Article ,030218 nuclear medicine & medical imaging ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,radiofrequency ,law ,medicine ,medicine.diagnostic_test ,business.industry ,image-guided thermal ablation ,ultrasound ,Ultrasound ,Cancer ,computed tomography ,Ablation ,medicine.disease ,lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,Oncology ,Tumor progression ,030220 oncology & carcinogenesis ,Referral center ,Radiology ,business - Abstract
Image-guided thermal ablations are increasingly applied in the treatment of renal cancers, under the guidance of ultrasound (US) or computed tomography (CT). Sometimes, multiple ablations are needed. The aim of the present study was to evaluate the long-term results in patients with renal mass treated with radiofrequency ablation (RFA) with both US and CT, with a focus on the multiple ablations rate. 149 patients (median age 67 years) underwent RFA from January 2008 to June 2015. Median tumor diameter was 25 mm (IQR 17&ndash, 32 mm). Median follow-up was 54 months (IQR 44&ndash, 68). 27 (18.1%) patients received multiple successful ablations, due to incomplete ablation (10 patients), local tumor progression (8 patients), distant tumor progression (4 patients) or multiple tumor foci (5 patients), with a primary and secondary technical efficacy of 100%. Complications occurred in 13 (8.7%) patients (6 grade A, 5 grade C, 2 grade D). 24 patients died during follow-up, all for causes unrelated to renal cancer. In conclusion, thermal ablations with the guidance of US and CT are safe and effective in the treatment of renal tumors in the long-term period, with a low rate of patients requiring multiple treatments over the course of their disease
- Published
- 2020