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1. Acute Pancreatitis in Pediatric Acute Lymphoblastic Leukemia (AcuPA Study). A Nationwide Survey in Poland

Author

Morawiak, Anna, primary, Salamonowicz, Małgorzata, additional, Królak, Aleksandra, additional, Kałwak, Krzysztof, additional, Owoc-Lempach, Joanna, additional, Kowalczyk, Jerzy, additional, Zawitkowska, Joanna, additional, Szczepański, Tomasz, additional, Irga-Jaworska, Ninela, additional, Adamkiewicz-Drożyńska, Elżbieta, additional, Albrecht, Katarzyna, additional, Szmydki-Baran, Anna, additional, Balwierz, Walentyna, additional, Czogała, Małgorzata, additional, Wachowiak, Jacek, additional, Derwich, Katarzyna, additional, Młynarski, Wojciech, additional, Zalewska-Szewczyk, Beata, additional, Krawczuk-Rybak, Maryna, additional, Sawicka- Żukowska, Małgorzata, additional, Styczyński, Jan, additional, Kołtan, Andrzej, additional, Safranow, Krzysztof, additional, Urasiński, Tomasz, additional, and Ociepa, Tomasz, additional

Published
2024
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2. Treatment Outcomes of Adolescents Compared to Younger Pediatric Patients with Acute Myeloid Leukemia: Do They Need a Special Approach?

Author

Pawińska-Wąsikowska, Katarzyna, primary, Czogała, Małgorzata, additional, Bukowska-Strakova, Karolina, additional, Surman, Marta, additional, Rygielska, Monika, additional, Książek, Teofila, additional, Sadowska, Beata, additional, Pac, Agnieszka, additional, Skalska-Sadowska, Jolanta, additional, Samborska, Magdalena, additional, Wachowiak, Jacek, additional, Ciebiera, Małgorzata, additional, Chaber, Radosław, additional, Tomaszewska, Renata, additional, Szczepański, Tomasz, additional, Zielezińska, Karolina, additional, Urasiński, Tomasz, additional, Moj-Hackemer, Małgorzata, additional, Kałwak, Krzysztof, additional, Kozłowska, Marta, additional, Irga-Jaworska, Ninela, additional, Sikorska-Fic, Barbara, additional, Łaguna, Paweł, additional, Muszyńska-Rosłan, Katarzyna, additional, Krawczuk-Rybak, Maryna, additional, Fałkowska, Anna, additional, Drabko, Katarzyna, additional, Bobeff, Katarzyna, additional, Młynarski, Wojciech, additional, Chodała-Grzywacz, Agnieszka, additional, Karolczyk, Grażyna, additional, Mycko, Katarzyna, additional, Badowska, Wanda, additional, Bartoszewicz, Natalia, additional, Styczyński, Jan, additional, Machnik, Katarzyna, additional, Mizia-Malarz, Agnieszka, additional, Balwierz, Walentyna, additional, and Skoczeń, Szymon, additional

Published
2024
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3. Characteristics and Outcome of FLT3-ITD-Positive Pediatric Acute Myeloid Leukemia—Experience of Polish Pediatric Leukemia and Lymphoma Study Group from 2005 to 2022

Author

Czogała, Małgorzata, primary, Czogała, Wojciech, additional, Pawińska-Wąsikowska, Katarzyna, additional, Książek, Teofila, additional, Bukowska-Strakova, Karolina, additional, Sikorska-Fic, Barbara, additional, Łaguna, Paweł, additional, Fałkowska, Anna, additional, Drabko, Katarzyna, additional, Muszyńska-Rosłan, Katarzyna, additional, Krawczuk-Rybak, Maryna, additional, Kozłowska, Marta, additional, Irga-Jaworska, Ninela, additional, Zielezińska, Karolina, additional, Urasiński, Tomasz, additional, Bartoszewicz, Natalia, additional, Styczyński, Jan, additional, Skalska-Sadowska, Jolanta, additional, Wachowiak, Jacek, additional, Rodziewicz-Konarska, Anna, additional, Kałwak, Krzysztof, additional, Ciebiera, Małgorzata, additional, Chaber, Radosław, additional, Mizia-Malarz, Agnieszka, additional, Chodała-Grzywacz, Agnieszka, additional, Karolczyk, Grażyna, additional, Bobeff, Katarzyna, additional, Młynarski, Wojciech, additional, Mycko, Katarzyna, additional, Badowska, Wanda, additional, Tomaszewska, Renata, additional, Szczepański, Tomasz, additional, Machnik, Katarzyna, additional, Zamorska, Natalia, additional, Balwierz, Walentyna, additional, and Skoczeń, Szymon, additional

Published
2023
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4. Pediatric Acute Myeloid Leukemia Post Cytotoxic Therapy—Retrospective Analysis of the Patients Treated in Poland from 2005 to 2022

Author

Czogała, Małgorzata, primary, Czogała, Wojciech, additional, Pawińska-Wąsikowska, Katarzyna, additional, Książek, Teofila, additional, Bukowska-Strakova, Karolina, additional, Sikorska-Fic, Barbara, additional, Łaguna, Paweł, additional, Skalska-Sadowska, Jolanta, additional, Wachowiak, Jacek, additional, Rodziewicz-Konarska, Anna, additional, Moj-Hackemer, Małgorzata, additional, Kałwak, Krzysztof, additional, Muszyńska-Rosłan, Katarzyna, additional, Krawczuk-Rybak, Maryna, additional, Fałkowska, Anna, additional, Drabko, Katarzyna, additional, Kozłowska, Marta, additional, Irga-Jaworska, Ninela, additional, Bobeff, Katarzyna, additional, Młynarski, Wojciech, additional, Tomaszewska, Renata, additional, Szczepański, Tomasz, additional, Chodała-Grzywacz, Agnieszka, additional, Karolczyk, Grażyna, additional, Mycko, Katarzyna, additional, Badowska, Wanda, additional, Zielezińska, Karolina, additional, Urasiński, Tomasz, additional, Bartoszewicz, Natalia, additional, Styczyński, Jan, additional, Balwierz, Walentyna, additional, and Skoczeń, Szymon, additional

Published
2023
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5. Viral Infection Profile in Children Treated for Acute Lymphoblastic Leukemia—Results of Nationwide Study

Author

Zawitkowska, Joanna, primary, Drabko, Katarzyna, additional, Czyżewski, Krzysztof, additional, Dziedzic, Magdalena, additional, Jaremek, Kamila, additional, Zalas-Więcek, Patrycja, additional, Szmydki-Baran, Anna, additional, Hutnik, Łukasz, additional, Matysiak, Michał, additional, Czogała, Wojciech, additional, Balwierz, Walentyna, additional, Żak, Iwona, additional, Salamonowicz-Bodzioch, Małgorzata, additional, Kazanowska, Bernarda, additional, Wróbel, Grażyna, additional, Kałwak, Krzysztof, additional, Tomaszewska, Renata, additional, Szczepański, Tomasz, additional, Zając-Spychała, Olga, additional, Wachowiak, Jacek, additional, Płonowski, Marcin, additional, Krawczuk-Rybak, Maryna, additional, Królak, Aleksandra, additional, Ociepa, Tomasz, additional, Urasiński, Tomasz, additional, Pierlejewski, Filip, additional, Młynarski, Wojciech, additional, Urbańska-Rakus, Justyna, additional, Machnik, Katarzyna, additional, Pająk, Sonia, additional, Badowska, Wanda, additional, Brzeski, Tomasz, additional, Mycko, Katarzyna, additional, Mańko-Glińska, Hanna, additional, Urbanek-Dądela, Agnieszka, additional, Karolczyk, Grażyna, additional, Mizia-Malarz, Agnieszka, additional, Stolpa, Weronika, additional, Skowron-Kandzia, Katarzyna, additional, Musiał, Jakub, additional, Chaber, Radosław, additional, Irga-Jaworska, Ninela, additional, Bień, Ewa, additional, and Styczyński, Jan, additional

Published
2022
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6. Advances in the First Line Treatment of Pediatric Acute Myeloid Leukemia in the Polish Pediatric Leukemia and Lymphoma Study Group from 1983 to 2019

Author

Czogała, Małgorzata, primary, Balwierz, Walentyna, additional, Pawińska-Wąsikowska, Katarzyna, additional, Książek, Teofila, additional, Bukowska-Strakova, Karolina, additional, Czogała, Wojciech, additional, Sikorska-Fic, Barbara, additional, Matysiak, Michał, additional, Skalska-Sadowska, Jolanta, additional, Wachowiak, Jacek, additional, Moj-Hackemer, Małgorzata, additional, Kałwak, Krzysztof, additional, Muszyńska-Rosłan, Katarzyna, additional, Krawczuk-Rybak, Maryna, additional, Grabowski, Dominik, additional, Kowalczyk, Jerzy, additional, Maciejka-Kembłowska, Lucyna, additional, Irga-Jaworska, Ninela, additional, Bobeff, Katarzyna, additional, Młynarski, Wojciech, additional, Tomaszewska, Renata, additional, Szczepański, Tomasz, additional, Chodała-Grzywacz, Agnieszka, additional, Karolczyk, Grażyna, additional, Mizia-Malarz, Agnieszka, additional, Mycko, Katarzyna, additional, Badowska, Wanda, additional, Zielezińska, Karolina, additional, Urasiński, Tomasz, additional, Urbańska-Rakus, Justyna, additional, Ciebiera, Małgorzata, additional, Chaber, Radosław, additional, Bartoszewicz, Natalia, additional, Wysocki, Mariusz, additional, and Skoczeń, Szymon, additional

Published
2021
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7. Infections with Klebsiella pneumoniae in Children Undergoing Anticancer Therapy or Hematopoietic Cell Transplantation: A Multicenter Nationwide Study.

Author

Sękowska A, Czyżewski K, Jaremek K, Zalas-Więcek P, Zając-Spychała O, Wachowiak J, Szmydki-Baran A, Hutnik Ł, Gietka A, Gryniewicz-Kwiatkowska O, Dembowska-Bagińska B, Semczuk K, Dzierżanowska-Fangrat K, Czogała W, Balwierz W, Żak I, Tomaszewska R, Szczepański T, Bień E, Irga-Jaworska N, Machnik K, Urbańska-Rakus J, Pająk S, Płonowski M, Krawczuk-Rybak M, Królak A, Ociepa T, Urasiński T, Wawryków P, Peregud-Pogorzelski J, Brzeski T, Mycko K, Mańko-Glińska H, Badowska W, Urbanek-Dądela A, Karolczyk G, Stolpa W, Skowron-Kandzia K, Mizia-Malarz A, Pierlejewski F, Młynarski W, Musiał J, Chaber R, Zawitkowska J, Zaucha-Prażmo A, Drabko K, Goździk J, Frączkiewicz J, Salamonowicz-Bodzioch M, Kałwak K, and Styczyński J

Abstract

Background: Klebsiella pneumoniae is a nosocomial pathogen that causes severe infections in immunocompromised patients. The aim of the study was to conduct a microbiological and clinical analysis of K. pneumoniae infections in children with malignancies or undergoing hematopoietic cell transplantation in Poland. Methods: We conducted a retrospective, multicenter study including children and adolescents under 19 years old treated between 2012 and 2021. We analyzed patients' characteristics, microbiological data, and the outcomes of antibiotic therapy. Results : A total of 9121 newly diagnosed children were treated for malignancy and 1697 pediatric patients underwent hematopoietic cell transplantation. K. pneumoniae infections were diagnosed in 527 patients. Their overall incidence was 4.86% in pediatric hematology and oncology patients and 4.95% in patients who underwent hematopoietic cell transplantation. The incidence of infection was higher in patients with acute leukemia than with solid tumors (7.8% vs. 4.1%; OR = 2.0; 95% CI = 1.6-2.4; p < 0.0001). The most frequent source of infection was in the urinary tract at 55.2%. More than 57% of K. pneumoniae strains were extended-spectrum β-lactamase-positive and almost 34% were multidrug-resistant. Infections with K. pneumoniae contributed to death in 3.22% of patients. Conclusions : K. pneumoniae is one of the most critical pathogens in children suffering from malignancies or undergoing hematopoietic cell transplantation. The incidence of multidrug-resistant K. pneumoniae strains is increasing and contributing to poor clinical outcome.

Published
2024
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