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This study introduces a novel tracking control strategy tailored to aeroengines, which are highly nonlinear and characterized by significant uncertainty. The proposed method entails a robust extended Kalman filter (REKF) enhanced by a forgetting factor for improved performance. An accompanying augmented, mixed onboard adaptive model based on the REKF precisely estimates and manages engine performance degradation. This advanced model effectively counters the degradation term in the perturbation block of the engine’s uncertain model. Using this strategic approach, a robust gain-scheduling controller was constructed and was found to outperform its predecessors, marking a notable advancement in control system design. Controlling twin rotor multi-input, multi-output (MIMO) systems is a highly complex process due to model uncertainties and unpredictable external disturbances. To address these challenges, we constructed an adaptive two-degree-of-freedom robust gain-scheduling controller (ATDF-RGSC) using a mixed sensitivity approach. Rigorous performance analysis confirms that this controller offers enhanced robustness, faster tracking, and more precise disturbance attenuation compared to other methods. These advanced control strategies successfully manage uncertainties and disturbances, improving performance metrics in both simulated and experimental scenarios. The proposed method may significantly enhance the safety and reliability of aeroengines and MIMO systems in practical applications.

Remaining useful life (RUL) prediction of aeroengines not only enhances aviation safety and operational efficiency but also significantly lowers operational costs, offering substantial economic and social benefits to the aviation industry. Aiming at RUL prediction, this paper proposes a novel dual-dimension convolutional-attention (DDCA) mechanism. DDCA consists of two branches: one includes channel attention and spatial attention mechanisms, while the other applies these mechanisms to the inverted dimensions. Pooling and feature-wise pooling operations are employed to extract features from different dimensions of the input data. These branches operate in parallel to capture more complex temporal and spatial feature correlations in multivariate time series data. Subsequently, an end-to-end DDCA-TCN network is constructed by integrating DDCA with a temporal convolutional network (TCN) for RUL prediction. The proposed prediction model is evaluated using the C-MAPSS dataset and compared to several state-of-the-art RUL prediction models. The results show that the RMSE and SCORE metrics of DDCA-TCN decreased by at least 12.8% and 4.6%, respectively, compared to other models on the FD002 subset, and by at least 10.6% and 18.4%, respectively, on the FD004 subset, which demonstrates that the DDCA-TCN model exhibits excellent performance in RUL prediction, particularly under multiple operating conditions.

Sensor health assessments are of great importance for accurately understanding the health of an aeroengine, supporting maintenance decisions, and ensuring flight safety. This study proposes an intelligent framework based on a physically guided neural network (PGNN) and convolutional neural network (CNN) to diagnose sensor faults under dynamic conditions. The strength of the approach is that it integrates information from physics-based performance models and deep learning models. In addition, it has the structure of prediction–residual–generation-fault classification that effectively decouples the interaction between sensor faults and system state changes. First, a PGNN generates the engine’s non-linear dynamic prediction output because the PGNN has the advantage of being able to handle temporal information from the long short-term memory (LSTM) network. We use a cross-physics–data fusion scheme as the prediction strategy to explore the hidden information of the physical model output and sensor measurement data. A novel loss function that considers physical discipline is also proposed to overcome the performance limitations of traditional data-driven models because of their physically inconsistent representations. Then, the predicted values of the PGNN are compared with the sensor measurements to obtain a residual signal. Finally, a convolutional neural network (CNN) is used to classify faults for residual signals and deliver diagnostic results. Furthermore, the feasibility of the proposed framework is demonstrated on an engine sensor fault dataset. The experimental results show that the proposed method outperforms the pure data-driven approach, with the predicted RMSE being reduced from 1.6731 to 0.9897 and the diagnostic accuracy reaching 95.9048%, thereby confirming its superior performance.

Arthritis is a general term for various types of inflammatory joint diseases. The most common clinical conditions are mainly represented by rheumatoid arthritis and osteoarthritis, which affect more than 4% of people worldwide and seriously limit their mobility. Arthritis medication generally requires long-term application, while conventional administrations by oral delivery or injections may cause gastrointestinal side effects and are inconvenient for patients during long-term application. Emerging microneedle (MN) technology in recent years has created new avenues of transdermal delivery for arthritis drugs due to its advantages of painless skin perforation and efficient local delivery. This review summarizes various types of arthritis and current therapeutic agents. The current development of MNs in the delivery of arthritis drugs is highlighted, demonstrating their capabilities in achieving different drug release profiles through different self-enhancement methods or the incorporation of nanocarriers. Furthermore, the challenges of translating MNs from laboratory studies to the clinical practice and the marketplace are discussed. This promising technology provides a new approach to the current drug delivery paradigm in treating arthritis in transdermal delivery.