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Graph-structured data, operating as an abstraction of data containing nodes and interactions between nodes, is pervasive in the real world. There are numerous ways dedicated to extract graph structure information explicitly or implicitly, but whether it has been adequately exploited remains an unanswered question. This work goes deeper by heuristically incorporating a geometric descriptor, the discrete Ricci curvature (DRC), in order to uncover more graph structure information. We present a curvature-based topology-aware graph transformer, termed Curvphormer. This work expands the expressiveness by using a more illuminating geometric descriptor to quantify the connections within graphs in modern models and to extract the desired structure information, such as the inherent community structure in graphs with homogeneous information. We conduct extensive experiments on a variety of scaled datasets, including PCQM4M-LSC, ZINC, and MolHIV, and obtain a remarkable performance gain on various graph-level tasks and fine-tuned tasks.

Despite the remarkable progress made in recent years, until today, the automatic detection of changes in synthetic aperture radar (SAR) images remains a difficult task due to speckle noise. This inherent multiplicative noise tends to increase false alarms and misdetections. As a solution, we developed an unsupervised method that detects SAR changes by analyzing structural differences. By this method, the spatial structure cues of a pixel are represented by a set of similarity weight vectors calculated from the non-local scale of the pixel. The difference image (DI) is then derived by measuring the structural consistency of the corresponding pixels. A new statistical distance that is insensitive to speckle noise was used to measure the similarity weights between patches in order to obtain an accurate structure. It was derived by applying the Nakagami–Rayleigh distribution to a statistical test and customizing the approximation based on change detection. The CFAR threshold estimator in conjunction with the Rayleigh hypothesis was then employed to attenuate the effect of the unimodal histogram of the DI. The results indicated that the proposed method reduces the false alarm rate and improves the kappa and F1-scores, while providing satisfactory visual results.

In this paper, we propose a method to enhance the performance of segmentation models for medical images. The method is based on convolutional neural networks that learn the global structure information, which corresponds to anatomical structures in medical images. Specifically, the proposed method is designed to learn the global boundary structures via an autoencoder and constrain a segmentation network through a loss function. In this manner, the segmentation model performs the prediction in the learned anatomical feature space. Unlike previous studies that considered anatomical priors by using a pre-trained autoencoder to train segmentation networks, we propose a single-stage approach in which the segmentation network and autoencoder are jointly learned. To verify the effectiveness of the proposed method, the segmentation performance is evaluated in terms of both the overlap and distance metrics on the lung area and spinal cord segmentation tasks. The experimental results demonstrate that the proposed method can enhance not only the segmentation performance but also the robustness against domain shifts.

Accumulated studies have shown that environmental factors (EFs) can regulate the expression of microRNA (miRNA) which is closely associated with several diseases. Therefore, identifying miRNA-EF associations can facilitate the study of diseases. Recently, several computational methods have been proposed to explore miRNA-EF interactions. In this paper, a novel computational method, MEI-BRWMLL, is proposed to uncover the relationship between miRNA and EF. The similarities of miRNA-miRNA are calculated by using miRNA sequence, miRNA-EF interaction, and the similarities of EF-EF are calculated based on the anatomical therapeutic chemical information, chemical structure and miRNA-EF interaction. The similarity network fusion is used to fuse the similarity between miRNA and the similarity between EF, respectively. Further, the multiple-label learning and bi-random walk are employed to identify the association between miRNA and EF. The experimental results show that our method outperforms the state-of-the-art algorithms.