1. [Use of chlotazol as an immunomodulating agent in chronic bronchitis].
- Author
-
Kleĭner AI, Shmuter LM, Makotchenko VM, Efremova VA, Khodzhaĭ IaI, and Trukh VS
- Subjects
- B-Lymphocytes pathology, Bronchitis immunology, Chronic Disease, Humans, Leukocyte Count drug effects, Lymphopenia etiology, T-Lymphocytes pathology, Adjuvants, Immunologic therapeutic use, Anti-Inflammatory Agents, Non-Steroidal therapeutic use, B-Lymphocytes immunology, Bronchitis drug therapy, Chloral Hydrate therapeutic use, Lymphopenia drug therapy, T-Lymphocytes immunology, Thiazoles therapeutic use
- Abstract
A positive immunomodulatory effect was found in chronic bronchitis patients examined immunologically before and after treatment including chlotazol. T- and B-cell immunity recovered, clinical condition of the patients improved. A combination of known antimicrobial and antiinflammatory effects with an uncovered immunomodulatory one made chlotazol a valuable modality in the treatment of chronic bronchitis associated with secondary immune deficiency.
- Published
- 1991