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Objective To draw a physiological and behavioral profile from patients treated at Policl nica established in the city of Londrina in order to identify the developments caused by the use of Anticholinesterasics and also to evaluate the main characteristics of those patients Method Cohort retrospective through the collection and analysis of data obtained from medical records from patients who fulfilled all the necessary criteria Results The average age of patients was years the majority being female and illiterate The majority did not present comorbidities such as stroke and traumatic Brain Injury TBI although have some cardiovascular disease associated The Basic Activity of Daily living ADLs from of the patients did not change between the current one and the one found at the diagnosis time The Mini Mental State Examination MMSE had its value unchanged in of the patients and had its high value at point in points in and in or more points in of the cases There was a decrease of the MMSE value in point in of the patients points in and or more points in Among the medicine used Donepezil was the most prevalent one followed by Galantamine and by Rivastigmine Besides the Memantine was associated to Donepezil in cases and to Galantamine in case Conclusion The results showed a correlation between Basics ADLs and TBI variables educational level and MMSE variation and family history of AD and cardiovascular disease The other risk and protective factors studied were not determinant for the outcome of the disease probably due to its multifactorial characteristic