1. [Cytological recognition of the histological types of lymphogranulomatosis in children].
- Author
-
Shcherbakova MG, Kolygin BA, and Puchkov IuG
- Subjects
- Child, Cytodiagnosis, Histiocytes pathology, Hodgkin Disease classification, Hodgkin Disease pathology, Humans, Lymph Nodes pathology, Lymphatic Diseases pathology, Lymphocyte Depletion, Sclerosis, Hodgkin Disease diagnosis
- Abstract
Examinations of punctates and impressions of lymph nodes from 68 children with primary untreated lymphogranulomatosis permitted to develop the criteria for differential cytological diagnosis of all types and variants of lymphogranulomatosis on the basis of histogenetic analysis and clinico-morphological comparisons, according to histological classification of the WHO. This proved to be possible only after it had been assumed that the original tumor cell must be a semi-stem cell of bone-marrow origin of histiocytic-reticular shoot which normally provides for physiological regeneration of reticular network of the lymph node. It appears that such a cell is a small lymphocyte-like cell with invaginated nucleus, the so-called small cleaved cell.
- Published
- 1978