1. Differentiating Arteriolosclerotic Ulcers of Martorell from Other Types of Leg Ulcers Based on Vascular Histomorphology
- Author
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Peter Petzelbauer, Kornelia Böhler, Julia Deinsberger, Philipp Tschandl, Benedikt Weber, Stanislava Tzaneva, Simon Bossart, Helmut Beltraminelli, Jonas Brugger, Barbara Meier-Schiesser, Florian Anzengruber, Jürg Hafner, University of Zurich, and Weber, B
- Subjects
medicine.medical_specialty ,histomorphology ,Arteriolosclerosis ,610 Medicine & health ,Dermatology ,Gastroenterology ,Diagnosis, Differential ,2708 Dermatology ,Discriminatory power ,martorell ,Arteriolosclerotic ,Internal medicine ,leg ulcer ,medicine ,Humans ,Ulcer ,business.industry ,10177 Dermatology Clinic ,General Medicine ,Odds ratio ,medicine.disease ,Confidence interval ,hyalinosis ,arteriolosclerosis ,RL1-803 ,Differential diagnosis ,business ,Pyoderma gangrenosum ,Calcification - Abstract
Clinical differential diagnosis of arteriolosclerotic ulcers of Martorell is challenging due to the lack of clearly affirmative instrument-based diagnostic criteria. The aim of this study was to develop vascular histomorphological diagnostic criteria differentiating Martorell ulcers from other types of leg ulcers. The histomorphology of patients diagnosed with arteriolosclerotic ulcers of Martorell (n���=���67) was compared with that of patients with venous leg ulcers, necrotizing leukocytoclastic vasculitis, pyoderma gangrenosum, and non-ulcerative controls (n���=���15 each). In a multivariable logistic regression model, the rates of arteriolar calcification (odds ratio (OR) 42.71, 95% confidence interval (CI) 7.43-443.96, p���
- Published
- 2021